Catalog No.
PHC14401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CFI (Lys19-Ile335).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Complement factor I,CFI,C3B/C4B inactivator,IF
Purification
Purified by antigen affinity column.
Accession
P05156
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Long-term GABA supplementation mitigates anxiety by modulating complement and neuroinflammatory pathways., PMID:40274802
A Case of Atypical Hemolytic Uremic Syndrome With a Complement Factor I Mutation Triggered by a Femoral Neck Fracture., PMID:40001340
mRNA vaccine-induced SARS-CoV-2 spike-specific IFN-γ and IL-2 T-cell responses are predictive of serological neutralization and are transiently enhanced by pre-existing cross-reactive immunity., PMID:39887249
Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in the presence of CD4-mimetics., PMID:39230306
Longitudinal Trajectories of the Cognitive Function Index in the A4 Study., PMID:39044492
Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies., PMID:39044488
Temperature-dependent Spike-ACE2 interaction of Omicron subvariants is associated with viral transmission., PMID:38953636
Adolescence-onset atypical hemolytic uremic syndrome: is it different from infant-onset?, PMID:38704765
A case-based narrative review of pregnancy-associated atypical hemolytic uremic syndrome/complement-mediated thrombotic microangiopathy., PMID:38408703
Complement-mediated thrombotic microangiopathy treated with anticomplement protein 5 therapy, a retrospective study., PMID:37984551
Eculizumab Versus Ravulizumab for the Treatment of Atypical Hemolytic Uremic Syndrome: A Systematic Review., PMID:37905269
Evaluation of the significance of complement-related genes mutations in atypical postinfectious glomerulonephritis: a pilot study., PMID:37845399
Atypical hemolytic uremic syndrome: genetically-based insights into pathogenesis through an analysis of the complement regulator CD46., PMID:39949759
Rare Variants in Complement Gene in C3 Glomerulopathy and Immunoglobulin-Mediated Membranoproliferative GN., PMID:37615951
Complement Factor I Gene Variant as a Treatable Cause of Recurrent Aseptic Neutrophilic Meningitis: A Case Report., PMID:37339889
A single-center experience of post-transplant atypical hemolytic uremic syndrome., PMID:37288831
Complement Inhibitors in the Management of Complement-Mediated Hemolytic Uremic Syndrome and Paroxysmal Nocturnal Hemoglobinuria., PMID:37104648
TMA in Kidney Transplantation., PMID:36944606
CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome., PMID:36755127
Variants in complement genes are uncommon in patients with anti-factor H autoantibody-associated atypical hemolytic uremic syndrome., PMID:36622444
Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function., PMID:36150362
An Infant Case of Streptococcus Pneumoniae-Associated Thrombotic Microangiopathy with Heterozygous CFI Mutation and CFHR3-CFHR1 Deletion., PMID:36070894
Complement Factor I Variants in Complement-Mediated Renal Diseases., PMID:35619721
A bibliometric review of peripartum cardiomyopathy compared to other cardiomyopathies using artificial intelligence and machine learning., PMID:35340600
Systematic review of atypical hemolytic uremic syndrome biomarkers., PMID:35118546
Talaromyces marneffei and Mycobacterium tuberculosis co-infection in a patient with high titer anti-interferon-γ autoantibodies: a case report., PMID:35090402
Pediatric Atypical Hemolytic Uremic Syndrome Advances., PMID:34944087
Evaluating Humoral Immunity against SARS-CoV-2: Validation of a Plaque-Reduction Neutralization Test and a Multilaboratory Comparison of Conventional and Surrogate Neutralization Assays., PMID:34787495
Measurement of coagulation factor antibody levels is useful for diagnosis and determining therapeutic efficacy in hemorrhagic patients with autoantibodies to coagulation factor VIII and factor V: results from a single center in Japan., PMID:34476734
HER2-targeted antibody-drug conjugate induces host immunity against cancer stem cells., PMID:33711257
Impact of time-varying cumulative bevacizumab exposures on survival: re-analysis of data from randomized clinical trial in patients with metastatic colo-rectal cancer., PMID:33422006
Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study., PMID:33270832
Molecular Studies and an ex vivo Complement Assay on Endothelium Highlight the Genetic Complexity of Atypical Hemolytic Uremic Syndrome: The Case of a Pedigree With a Null CD46 Variant., PMID:33224962
Anti-complement factor I antibody associated atypical hemolytic uremic syndrome - A new insight for future perspective!, PMID:32962820
Phase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08., PMID:32863385
Computational classification of core and outer fucosylation of N-glycoproteins in human plasma using collision-induced dissociation in mass spectrometry., PMID:32754952
Anti-complement factor H autoantibodies may be protective in lupus nephritis., PMID:32387092
Specific T-cell immune responses against colony-forming cells including leukemic progenitor cells of AML patients were increased by immune checkpoint inhibition., PMID:32020256
Cocaine-associated atypical haemolytic uraemic syndrome in a genetically susceptible individual., PMID:31900968
Simulation of continuous low pH viral inactivation inside a coiled flow inverter., PMID:31868222
Rare Genetic Variants in Jewish Patients Suffering from Age-Related Macular Degeneration., PMID:31635417
Simulation of pH level distribution inside a coiled flow inverter for continuous low pH viral inactivation., PMID:31631326
Rare Functional Variants in Complement Genes and Anti-FH Autoantibodies-Associated aHUS., PMID:31118930
A Randomized Phase 2 Study of an Anti-Amyloid β Monoclonal Antibody in Geographic Atrophy Secondary to Age-Related Macular Degeneration., PMID:31047490
Treatment of hemolytic uremic syndrome related to Bordetella pertussis infection -is plasma exchange or eculizumab use necessary?, PMID:30558570
Virus study for continuous low pH viral inactivation inside a coiled flow inverter., PMID:30450694
Intrarenal Complement System Transcripts in Chronic Antibody-Mediated Rejection and Recurrent IgA Nephropathy in Kidney Transplantation., PMID:30356754
Immunological features and functional analysis of anti-CFH autoantibodies in patients with atypical hemolytic uremic syndrome., PMID:30315407
A monoclonal antibody targeting amyloid β (Aβ) restores complement factor I bioactivity: Potential implications in age-related macular degeneration and Alzheimer's disease., PMID:29782502
For research use only. Not for human or drug use.
