Catalog No.
PHC12901
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CYP17A1 (Cys183-Thr508).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Steroid 17-alpha-hydroxylase/17,20 lyase,CYPXVII,Cytochrome P450 17A1,Cytochrome P450-C17,Steroid 17-alpha-monooxygenase,17-alpha-hydroxyprogesterone aldolase,CYP17A1,S17AH,Cytochrome P450c17,CYP17
Purification
Purified by antigen affinity column.
Accession
P05093
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Bimodal genomic approach predicting Semaphorin 7A (SEMA7A) as prognostic biomarker in adrenocortical carcinoma., PMID:40291702
Effect of Treatment on Steroidome in Women with Multiple Sclerosis., PMID:40076462
Dihydroberberine alleviates Th17/Treg imbalance in premature ovarian insufficiency mice via inhibiting Rheb/mTOR signaling., PMID:39472803
Testicular mosaicism in non-mosaic postpubertal Klinefelter patients with focal spermatogenesis and in non-mosaic prepubertal Klinefelter boys., PMID:39198007
Characterization of Potential Target Genes of Borneol in Increasing Trastuzumab Sensitivity in HER2+ Trastuzumab-Resistant Breast Cancer: Bioinformatics and In Vitro Studies., PMID:38809634
Role of p57KIP2 in Stem and Progenitor Leydig Cells of Mouse Testes., PMID:38772531
Genetic diagnosis and clinical analysis of 17α-hydroxylase/17, 20-lyase deficiency combined with type 2 diabetes mellitus: A case report., PMID:38206738
Concomitant occurence of multiple autoantibodies against human cytochromes P450., PMID:34464888
Dulaglutide, a long-acting GLP-1 receptor agonist, can improve hyperandrogenemia and ovarian function in DHEA-induced PCOS rats., PMID:34375684
Impairment of testes development in Yangzhou ganders by augmentation of leptin receptor signaling., PMID:34051590
Neurotrophin-3 stimulates stem Leydig cell proliferation during regeneration in rats., PMID:33090725
Dose- dependent ameliorative effects of quercetin and l-Carnitine against atrazine- induced reproductive toxicity in adult male Albino rats., PMID:29710542
Establishment of an in vitro culture model of theca cells from hierarchical follicles in ducks., PMID:28432272
Disordered zonal and cellular CYP11B2 enzyme expression in familial hyperaldosteronism type 3., PMID:27793677
Immunohistochemistry of the adrenal in primary aldosteronism., PMID:27119751
Autoantibodies against Cytochrome P450 Side-Chain Cleavage Enzyme in Dogs (Canis lupus familiaris) Affected with Hypoadrenocorticism (Addison's Disease)., PMID:26618927
Intratumoral heterogeneity of steroidogenesis in aldosterone-producing adenoma revealed by intensive double- and triple-immunostaining for CYP11B2/B1 and CYP17., PMID:26597777
CYP17A1 gene polymorphisms and environmental exposure to organochlorine pesticides contribute to the risk of small for gestational age., PMID:25064838
Targeting the androgen receptor in prostate cancer., PMID:24890318
Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype., PMID:24706793
Novel gonadal characteristics in an aged bovine freemartin., PMID:24630042
The increased number of Leydig cells by di(2-ethylhexyl) phthalate comes from the differentiation of stem cells into Leydig cell lineage in the adult rat testis., PMID:23391632
Research on the steroidogenesis of proliferated Leydig cells in vitro., PMID:23322215
IGF2 increases de novo steroidogenesis in prostate cancer cells., PMID:23319492
Cyp17a1 and Cyp19a1 in the zebrafish testis are differentially affected by oestradiol., PMID:23283575
Cytochrome b(5) forms homomeric complexes in living cells., PMID:22878120
Insulin-like growth factor 3 regulates expression of genes encoding steroidogenic enzymes and key transcription factors in the Nile tilapia gonad., PMID:22337331
Emerging treatments for castrate-resistant prostate cancer., PMID:21984773
Interleukins 1α and 1β as regulators of steroidogenesis in human NCI-H295R adrenocortical cells., PMID:21600230
Development of steroid signaling pathways during primordial follicle formation in the human fetal ovary., PMID:21430025
Fetal testis dysgenesis and compromised Leydig cell function in Tgfbr3 (beta glycan) knockout mice., PMID:19696014
For research use only. Not for human or drug use.
