Catalog No.
DHD71001
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Target
S100A4, Protein S100-A4, S100 calcium-binding protein A4, Calvasculin, Protein Mts1, MTS1, CAPL, Placental calcium-binding protein, Metastasin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P26447
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
LK-1, LK 1, LK1
Clone ID
LK-1
Potential of bone marrow mesenchymal stem cells in iodine-induced autoimmune thyroiditis therapy., PMID:40435196
Molecular Hydrogen Ameliorates Anti-Desmoglein 1 Antibody-Induced Pemphigus-Associated Interstitial Lung Disease by Inhibiting Oxidative Stress., PMID:40362440
The multi-faceted immune modulatory role of S100A4 in cancer and chronic inflammatory disease., PMID:40078995
CTGF (CCN2): a multifaceted mediator in breast cancer progression and therapeutic targeting., PMID:39945880
A mucosal vaccine formulation against tuberculosis by exploiting the adjuvant activity of S100A4-A damage-associated molecular pattern molecule., PMID:39089961
Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck squamous cell carcinoma cells when cocultured in spheroids., PMID:38822309
Anti-S100A4 monoclonal antibody treatment ameliorates experimental skin fibrosis and SSc-specific transcriptional signatures in human skin: Comment on the targeting S100A4 is helpful in SSc treatment by Trinh-Minh et al., PMID:38351303
Immunocompetent mouse models revealed that S100A4+ monocytes/macrophages facilitate long-term Zika virus infection in the testes., PMID:38164719
Effect of Anti-S100A4 Monoclonal Antibody Treatment on Experimental Skin Fibrosis and Systemic Sclerosis-Specific Transcriptional Signatures in Human Skin., PMID:38108109
Anti-S100A4 antibody administration alleviates bronchial epithelial-mesenchymal transition in asthmatic mice., PMID:37873538
Impact of glycogen synthase kinase-3ß inhibition on rats' temporomandibular joint collagen-induced rheumatoid arthritis with correlation to miRNA-155/miRNA-24 expression., PMID:37667918
Prognostic value of S100A4 and Glypican-3 in hepatocellular carcinoma in cirrhotic HCV patients., PMID:37599312
Clinical and pathogenic significance of S100A4 overexpression in systemic sclerosis., PMID:37414521
S100A4-neutralizing monoclonal antibody 6B12 counteracts the established experimental skin fibrosis induced by bleomycin., PMID:37314987
Contribution of S100A4-expressing fibroblasts to anti-SSA/Ro-associated atrioventricular nodal calcification and soluble S100A4 as a biomarker of clinical severity., PMID:37090702
Secreted S100A4 causes asthmatic airway epithelial barrier dysfunction induced by house dust mite extracts via activating VEGFA/VEGFR2 pathway., PMID:36883729
S100A4 is expressed in human odontoblasts and odontoblast-like cells., PMID:36327571
RNA Sequencing of Idiopathic Subglottic Stenosis Tissues Uncovers Putative Profibrotic Mechanisms and Identifies a Prognostic Biomarker., PMID:35948078
S100A4 exerts robust mucosal adjuvant activity for co-administered antigens in mice., PMID:35729204
Bile cytology diagnosis in challenging cases: Validation of diagnostic bile cytology criteria and extensive study for immunocytochemical markers., PMID:34981669
The potential value of amlexanox in the treatment of cancer: Molecular targets and therapeutic perspectives., PMID:34968491
Role of Advanced Glycation End-Products and Other Ligands for AGE Receptors in Thyroid Cancer Progression., PMID:34575195
S100A4 Is Critical for a Mouse Model of Allergic Asthma by Impacting Mast Cell Activation., PMID:34367151
Whole Genome Gene Expression: Histologic and Immunohistologic Study of Grafted Bone Using Allograft and Xenograft., PMID:33909719
Characterization of neoplastic cells outlining the cystic space of invasive micropapillary carcinoma of the canine mammary gland., PMID:33761962
S100A4 in Spinal Substantia Gelatinosa from Dorsal Root Ganglia Modulates Neuropathic Pain in a Rodent Spinal Nerve Injury Model., PMID:33732013
The role of S100A4 for bone metastasis in prostate cancer cells., PMID:33549040
Mode-splitting in a microring resonator for self-referenced biosensing., PMID:33362120
Quiescent and Activated Fibroblasts in Lateral Ventricular Meningioma With a Dura-like Membrane., PMID:33316485
Distinguished properties of cells isolated from the dentin-pulp interface., PMID:33212174
Neutralization of S100A4 induces stabilization of atherosclerotic plaques: role of smooth muscle cells., PMID:33135065
SASP-induced macrophage dysfunction may contribute to accelerated senescent fibroblast accumulation in the dermis., PMID:33010063
Hedgehog pathway activation in oral squamous cell carcinoma: cancer-associated fibroblasts exhibit nuclear GLI-1 localization., PMID:33000351
Anti-S100A4 Antibody Therapy Is Efficient in Treating Aggressive Prostate Cancer and Reversing Immunosuppression: Serum and Biopsy S100A4 as a Clinical Predictor., PMID:32999046
Keratinocyte-specific deletion of SHARPIN induces atopic dermatitis-like inflammation in mice., PMID:32687504
S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma., PMID:31857700
S100A4 released from highly bone-metastatic breast cancer cells plays a critical role in osteolysis., PMID:31667000
S100A4 promotes inflammation but suppresses lipid accumulation via the STAT3 pathway in chronic ethanol-induced fatty liver., PMID:31321478
The role of vascular endothelial growth factor receptor 1 tyrosine kinase signaling in bleomycin-induced pulmonary fibrosis., PMID:31176171
Microvascular pathology in Friedreich cardiomyopathy., PMID:31166002
Elevated S100A4 in asthmatics and an allergen-induced mouse asthma model., PMID:30569582
Helicobacter pylori Infection-Induced Hepatoma-Derived Growth Factor Regulates the Differentiation of Human Mesenchymal Stem Cells to Myofibroblast-Like Cells., PMID:30513684
Comparison of renal lesions in cats and dogs using pathomorphological and ımmunohistochemical methods., PMID:30328730
S100A4 promotes colon inflammation and colitis-associated colon tumorigenesis., PMID:30221056
Effects of CTLA4-Ig treatment on circulating fibrocytes and skin fibroblasts from the same systemic sclerosis patients: an in vitro assay., PMID:30053831
Calcimycin Suppresses S100A4 Expression and Inhibits the Stimulatory Effect of Transforming Growth Factor β1 on Keloid Fibroblasts., PMID:29846215
S100A4 blockage alleviates agonistic anti-CD137 antibody-induced liver pathology without disruption of antitumor immunity., PMID:29632708
The role of S100A4 protein in anticancer cytotoxicity: its presence is required on the surface of CD4+CD25+PGRPs+S100A4+ lymphocyte and undesirable on the surface of target cells., PMID:29251175
Clearance of plasmin-PN-1 complexes by vascular smooth muscle cells in human aneurysm of the ascending aorta., PMID:29149696
Deficiency in Calcium-Binding Protein S100A4 Impairs the Adjuvant Action of Cholera Toxin., PMID:28951732
For research use only. Not for human or drug use.
