Catalog No.
DHC15809
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Applications
Research Grade Biosimilar
Target
Hybridoma growth factor, BSF-2, IFN-beta-2, CDF, IL6, Interleukin-6, IL-6, B-cell stimulatory factor 2, Interferon beta-2, IFNB2, CTL differentiation factor
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05231
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
SK2
Clone ID
SK2
Note
For research use only. Not suitable for clinical or therapeutic use.
[Protective аction of ginseng root extract on myofibril apoptosis and immune response in rats after exhausting physical exercise. Part II. Effect of ginseng root extract on immunity and regulation of energy metabolism]., PMID:40418135
Phase 1b/2 study of ADG106, a 4-1BB/CD137 agonist, in combination with toripalimab in patients with advanced solid tumors., PMID:40421181
Interactions of Probiotics with the Immune Cells of Patients with COVID-19 Pneumonia., PMID:40424990
Immunocytokines and cytokine neutralization for cancer immunotherapy., PMID:40425444
C1q Binds to CD4+ T Cells and Inhibits the Release of Pro-Inflammatory Cytokines: Role in the Pathogenesis of Systemic Lupus Erythematosus., PMID:40429614
OVA-Induced Food Allergy Leads to Neurobehavioral Changes in Mice and the Potential Role of Gut Microbiota and Metabolites Dysbiosis., PMID:40429903
A Modular Mathematical Model of the Immune Response for Investigating the Pathogenesis of Infectious Diseases., PMID:40431602
A case of Schnitzler syndrome complicated by rheumatoid arthritis treated with methotrexate., PMID:40433863
IL-6 Inhibitors and TNF Inhibitors: Impact on Exercise-induced Cardiac Adaptations in Patients With Rheumatoid Arthritis., PMID:40436519
Itaconate derivative 4-OI inhibits M1 macrophage polarization and restores its impaired function in immune thrombocytopenia through metabolic reprogramming., PMID:40437667
Antibody-mediated Rejection - Treatment Standard., PMID:40440205
Immunostimulatory effects of multiple short-hairpin RNAs enhance foot-and-mouth disease vaccine-induced humoral immunity., PMID:40441607
Epstein-Barr virus infection increases the risk of depression: A cross-sectional study and Mendelian randomization analysis., PMID:40441653
Differences in Aqueous Humor Cytokine Concentrations According to the Presence of Posterior Subcapsular Cataract: A Prospective Case-Control Study., PMID:40441712
Soil-Transmitted Helminths and the Intricacies of Immunoregulation: Evidence From Amazonian Ecuador for the Importance of Considering Species-Specific Effects Within the Old Friends Hypothesis., PMID:40444920
The recombinant anti-MET/EpCAM bispecific antibody fragment: a promising novel therapeutic approach for breast cancer treatment., PMID:40445574
Immune responses and recovery from spotty liver disease in layer birds., PMID:40446677
Multi-omics analysis reveals Angelica sinensis-Carthamus tinctorius herb pair ameliorates diabetic retinopathy comorbid with depressive symptoms via the gut-eye-brain axis., PMID:40449450
A Spanish Porcine Reproductive and Respiratory Syndrome Virus 1 Strain Is Highly Virulent in Pigs Under Experimental Conditions., PMID:40453458
Longitudinal analysis of cytokine dynamics in severe fever with thrombocytopenia syndrome patients - High-incidence regions of China (2010-2023)., PMID:40453472
The role of IGF-2 and its variants in enhancing endothelial migration and angiogenesis., PMID:40454313
Several Common Genetic Variations Associate With Functional or Anatomic Effects of Anti-VEGF Treatment in Conditions With Macular Edema., PMID:40455044
Toll-like receptor engaged in activation and osteoimmuno-cytokines production by unswitched memory B cells during periodontitis., PMID:40455294
Alternation of anti-NMDA receptor subunit GluN2 antibody in a patient with SLE who promptly developed anxiety after belimumab., PMID:40455606
IL-6: a pivotal molecule for tumor-brain dysfunction interaction., PMID:40461299
RNase 7 and Th cytokines synergistically increase the secretion of interleukin-6 from keratinocytes., PMID:40461723
Glutamine and Isoleucine as the Key Amino Acids in Major IgE Linear Epitopes of α-Lactalbumin Identified by the Immune Peptide Microarray Assay For Chinese Bovine Milk Allergy., PMID:40462490
Novel Aptamers Targeting Sclerostin Loop3 Improve Skeletal and Muscle Properties Without Adverse Cardiovascular Effects in Orchiectomized Mice., PMID:40464222
[Correlation between soluble CD146 and systemic vasculitis]., PMID:40484821
Adaptive immune changes in colorectal cancer: a focus on T and B cell activation genes., PMID:40484866
The role of cytokines in pediatric hematologic malignancies: mechanisms of tumor progression and therapeutic implications - a narrative review., PMID:40486628
Activin A exacerbates neonatal necrotizing enterocolitis via ALK4-mediated apoptosis and barrier disruption., PMID:40494204
Effects of Rhodobacter sphaeroides protein on growth performance, nutrient digestibility, rumen fermentation, and serum metabolites in dairy calves during the pre- and postweaning periods., PMID:40499903
Adipose-Derived Mesenchymal Stromal/Stem Cells Reduce Inflammatory Responses and Partially Alleviate Skin Symptoms in Imiquimod-Induced Psoriasis-Like Dermatitis Model Mice., PMID:40500215
Chronic administration of morphine provokes generation of antibodies to morphine and immunosuppression in individuals with opioid use disorder., PMID:40501089
Inflammatory arthritis immune related adverse events represent a unique autoimmune disease entity primarily driven by T cells, but likely not autoantibodies., PMID:40502578
CTRP7 as a molecular biomarker associating with responsiveness to pulmonary vasodilators: insights from human and animal studies in pulmonary arterial hypertension., PMID:40504501
FcRn inhibitors in immune thrombocytopenia: A comprehensive review of therapeutic advances and clinical outcomes., PMID:40505332
Anti-Tumor Activities of Anti-Siglec-15 Chimeric Heavy-Chain Antibodies., PMID:40507880
A Mixture of Free and Microencapsulated Essential Oils Combined with Turmeric and Tannin in the Diet of Dairy Cows: Effects on Productive Efficiency and Animal Health., PMID:40509055
Role of Ocrelizumab in modulating gene and microRNA expression in multiple sclerosis., PMID:40510879
TNFα signaling restores steady-state hematopoiesis in a TNFαKO mouse model of anemia of inflammation., PMID:40512402
Pilot study of ABO-isogroup or universal plasma pools with or without pathogen reduction treatment., PMID:40522315
Generation and Biological Characterization of an Anti-IL-6Rα Biosimilar Candidate Antibody., PMID:40524396
Inflammatory signatures and immunomodulation in neonates: a pilot study., PMID:40525368
Immune response to and virological profile of SARS-CoV-2 before and after symptom onset in individuals vaccinated with inactivated COVID-19 vaccines., PMID:40530661
Conserved domains of flagellin as adjuvants for an inactivated vaccine against porcine epidemic diarrhea virus., PMID:40532846
Optimised nanobody-based quenchbodies for enhanced protein detection., PMID:40533519
Direct Interleukin-6 Inhibition Blunts Arterial Thrombosis by Reducing Collagen-Mediated Platelet Activation., PMID:40534557
Pro-dermcidin and derivatives as potential therapeutics for lethal experimental sepsis., PMID:40534887
For research use only. Not for human or drug use.
