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Research Grade Anti-Human IL2 (AU 007)

Catalog #:   DHF36802 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHF36802

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

IL2, IL-2, Aldesleukin, Interleukin-2, TCGF, T-cell growth factor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P60568

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

AU-007, AU 007, AU007

Clone ID

AU 007

Data Image
References

Tumor-Associated NK Cells Regulate Distinct CD8+ T-cell Differentiation Program in Cancer and Contribute to Resistance against Immune Checkpoint Blockers., PMID:40530506

Oral administration of Lactiplantibacillus plantarum GKK1 ameliorates atopic dermatitis in a mouse model., PMID:40529585

Immunogenicity of the Comirnaty Omicron XBB.1.5 booster COVID-19 mRNA vaccine in patients with cirrhosis., PMID:40525725

[Research on the inhibitory effects of evodiamine on activated T cell proliferation]., PMID:40525340

In Vitro Culture for H5N1-Specific Duck T Cells and Detection of Immune Responses Using Intracellular Cytokine Staining Method., PMID:40522882

Effect of Metformin on vascular endothelial injury in patients with non-small cell lung cancer treated with chemotherapy combined with bevacizumab., PMID:40522519

Anti-melanoma differentiation-associated gene 5 antibody associated rapidly progressive interstitial lung disease in a pediatric patient: a case report., PMID:40514742

Mechanistic investigation of calcium phosphate mineralization potentiating the cellular immune response of foot-and-mouth disease virus-like particle vaccines., PMID:40512119

Expanded adaptive NKG2C+ NK cells exhibit potent ADCC and functional responses against HBV-infected hepatoma cell lines., PMID:40501566

IL-18 favors Th2 responses in sporotrichosis caused by Sporothrix globosa, prolonging the course of the disease., PMID:40489556

Anti-TNFR2 antibody and HMGN1 combined with TIL cell therapy inhibits colorectal cancer progression by enhancing immune response., PMID:40483876

Optimizing delivery in a multivalent subunit influenza vaccine using mixed polymeric microparticle degradation rates., PMID:40482923

Spatially Tuned Localization of Interleukins and OX40 Agonists Enhances Synergistic Anti-Tumor Immunity., PMID:40475557

Advances of oncolytic vaccinia viruses armed with interleukin in tumor therapy., PMID:40469178

The immunosuppressive effect of glucocorticoids in human primary T cells is mainly mediated via a rapid inhibition of the IL-2/IL-2R signaling axis., PMID:40468327

T-cell activation enhances anti-HER2-mediated antibody-dependent cellular cytotoxicity in gastric cancer., PMID:40455140

Chimeric antigen receptors discriminate between tau and distinct amyloid-beta species., PMID:40448101

Development of a Cell Membrane-Anchored Aptamer Sensor for IL-2 Detection In Situ., PMID:40447990

Differences in Aqueous Humor Cytokine Concentrations According to the Presence of Posterior Subcapsular Cataract: A Prospective Case-Control Study., PMID:40441712

Prolonged effects of adenoviral vector priming on T-cell cytokine production in heterologous adenoviral vector/mRNA COVID-19 vaccination regimens., PMID:40436912

Chlamydia muridarum mutant CM-pGP3S as a novel attenuated live rectal vaccine protects against genital tract infection., PMID:40433661

Immunogenicity of an Intranasal Dual (Core and Surface)-Antigen Vaccine Against Hepatitis B Virus Enhanced by Carboxyl-Vinyl Polymer Excipients., PMID:40432076

Enhancing H11 Protein-Induced Immune Protection Against Haemonchus contortus in Goats: A Nano-Adjuvant Formulation Strategy., PMID:40427752

Immunocytokines and cytokine neutralization for cancer immunotherapy., PMID:40425444

Immunogenicity evaluation of a recombinant pseudorabies virus co-expressing PCV2 and PCV3 capsid proteins in mice and piglets., PMID:40424702

Safety toxicology of an IL-2 'no-alpha' mutein in the Sprague-Dawley rat following repeated dosing via intravenous administration., PMID:40417611

Intrathecal nivolumab and IL-2 for treatment of leptomeningeal metastases in EGFR-mutated lung adenocarcinoma., PMID:40412102

Tumor suppressing function of SLC16A7 in bladder cancer and its pan-cancer analysis., PMID:40410718

Evaluation of humoral and cellular immune responses in healthcare workers with varying levels of SARS-CoV-2 exposure: effects of CoronaVac vaccination followed by heterologous booster., PMID:40406109

IL-2 detected by flow cytometry and its significance in systemic lupus erythematosus., PMID:40402317

Systemic secukinumab treatment in patients with ankylosing spondylitis: the relationship between systemic and tear proinflammatory cytokines and ocular surface findings-a pilot study., PMID:40394377

Immune efficacy of oprH chitosan nanoparticle DNA vaccine against Pseudomonas aeruginosa., PMID:40386097

Сomprehensive approach to comparative characteristics of clinical and laboratory parameters of the study in children - in 6 months after Covid-19 treatment and 6 months after Covid-19 vaccination., PMID:40367469

The Combination of Oncolytic Virus and Antibody Blockade of TGF-β Enhances the Efficacy of αvβ6-Targeting CAR T Cells Against Pancreatic Cancer in an Immunocompetent Model., PMID:40361460

Development and Potent Anti-Tumor Activity of a Fully Humanized Anti-TAG-72-IL-2 Fusion Protein for Therapy of Solid Tumors., PMID:40361381

Relation of Cytokine Profile and Antibody Values to Post-Translational Protein Modifications in Patients with Rheumatoid Arthritis (Preliminary Data)., PMID:40353964

Bifidobacterium longum BL300 alleviates DSS-induced Colitis by promoting IgA-mediated Gut Microbiota homeostasis., PMID:40350789

Combinatorial treatment with upadacitinib abrogates systemic toxicity of a tumor-targeted IL-2 fusion protein., PMID:40350206

HIF-PH inhibitors induce pseudohypoxia in T cells and suppress the growth of microsatellite stable colorectal cancer by enhancing antitumor immune responses., PMID:40343532

Generating potent and persistent antitumor immunity via affinity-tuned CAR-T cells targeting mesothelin., PMID:40341217

PD-1 blockade employed at the time CD8+ T cells are activated enhances their antitumor efficacy., PMID:40341032

ZFP36-family RNA-binding proteins in regulatory T cells reinforce immune homeostasis., PMID:40328742

Antifibrotic effects of IL-12-treated natural killer cells on collagen type I regulation in lung fibroblasts., PMID:40328414

Next-generation probiotics Alistipes onderdonkii enhances the efficacy of anti-PD-1 therapy in colorectal cancer., PMID:40328413

Ex vivo pembrolizumab pharmacology for personalized PD-1 inhibitor therapy reveals a critical gap between receptor occupancy and T cell functionality., PMID:40318274

Investigating tumor immunogenicity as a determinant of differential abscopal effects., PMID:40302523

Receptor-based bioassay for functional IL-2 quantification., PMID:40300311

Immunomodulatory potential of phosphorus: insights from experimental mice models under normal and immunosuppressive condition., PMID:40294527

PF-08046032: A novel, investigational CD25-directed antibody-drug conjugate optimized for selective depletion of regulatory T cells in advanced malignant tumors., PMID:40293942

Association Between Diabetes Mellitus and Allergic Diseases Sensitized by Different Allergens and the Potential Mechanism of Diabetes Mellitus Affecting Ovalbumin-Induced Allergic Rhinitis., PMID:40289517

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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For research use only. Not for human or drug use.

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Research Grade Anti-Human IL2 (AU 007) [DHF36802]
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