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Research Grade Anti-Human IL2 (AU 007)

Catalog #:   DHF36802 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHF36802

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Applications

Research Grade Biosimilar

Target

IL2, IL-2, Aldesleukin, Interleukin-2, TCGF, T-cell growth factor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P60568

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

AU-007, AU 007, AU007

Clone ID

AU 007

Note

For research use only. Not suitable for clinical or therapeutic use.

Data Image
References

Association Between Diabetes Mellitus and Allergic Diseases Sensitized by Different Allergens and the Potential Mechanism of Diabetes Mellitus Affecting Ovalbumin-Induced Allergic Rhinitis., PMID:40289517

PF-08046032: A novel, investigational CD25-directed antibody-drug conjugate optimized for selective depletion of regulatory T cells in advanced malignant tumors., PMID:40293942

Immunomodulatory potential of phosphorus: insights from experimental mice models under normal and immunosuppressive condition., PMID:40294527

Receptor-based bioassay for functional IL-2 quantification., PMID:40300311

Investigating tumor immunogenicity as a determinant of differential abscopal effects., PMID:40302523

Ex vivo pembrolizumab pharmacology for personalized PD-1 inhibitor therapy reveals a critical gap between receptor occupancy and T cell functionality., PMID:40318274

Next-generation probiotics Alistipes onderdonkii enhances the efficacy of anti-PD-1 therapy in colorectal cancer., PMID:40328413

Antifibrotic effects of IL-12-treated natural killer cells on collagen type I regulation in lung fibroblasts., PMID:40328414

ZFP36-family RNA-binding proteins in regulatory T cells reinforce immune homeostasis., PMID:40328742

PD-1 blockade employed at the time CD8+ T cells are activated enhances their antitumor efficacy., PMID:40341032

Generating potent and persistent antitumor immunity via affinity-tuned CAR-T cells targeting mesothelin., PMID:40341217

HIF-PH inhibitors induce pseudohypoxia in T cells and suppress the growth of microsatellite stable colorectal cancer by enhancing antitumor immune responses., PMID:40343532

Combinatorial treatment with upadacitinib abrogates systemic toxicity of a tumor-targeted IL-2 fusion protein., PMID:40350206

Bifidobacterium longum BL300 alleviates DSS-induced Colitis by promoting IgA-mediated Gut Microbiota homeostasis., PMID:40350789

Relation of Cytokine Profile and Antibody Values to Post-Translational Protein Modifications in Patients with Rheumatoid Arthritis (Preliminary Data)., PMID:40353964

Development and Potent Anti-Tumor Activity of a Fully Humanized Anti-TAG-72-IL-2 Fusion Protein for Therapy of Solid Tumors., PMID:40361381

The Combination of Oncolytic Virus and Antibody Blockade of TGF-β Enhances the Efficacy of αvβ6-Targeting CAR T Cells Against Pancreatic Cancer in an Immunocompetent Model., PMID:40361460

Сomprehensive approach to comparative characteristics of clinical and laboratory parameters of the study in children - in 6 months after Covid-19 treatment and 6 months after Covid-19 vaccination., PMID:40367469

Immune efficacy of oprH chitosan nanoparticle DNA vaccine against Pseudomonas aeruginosa., PMID:40386097

Systemic secukinumab treatment in patients with ankylosing spondylitis: the relationship between systemic and tear proinflammatory cytokines and ocular surface findings-a pilot study., PMID:40394377

IL-2 detected by flow cytometry and its significance in systemic lupus erythematosus., PMID:40402317

Evaluation of humoral and cellular immune responses in healthcare workers with varying levels of SARS-CoV-2 exposure: effects of CoronaVac vaccination followed by heterologous booster., PMID:40406109

Tumor suppressing function of SLC16A7 in bladder cancer and its pan-cancer analysis., PMID:40410718

Intrathecal nivolumab and IL-2 for treatment of leptomeningeal metastases in EGFR-mutated lung adenocarcinoma., PMID:40412102

Safety toxicology of an IL-2 'no-alpha' mutein in the Sprague-Dawley rat following repeated dosing via intravenous administration., PMID:40417611

Immunogenicity evaluation of a recombinant pseudorabies virus co-expressing PCV2 and PCV3 capsid proteins in mice and piglets., PMID:40424702

Immunocytokines and cytokine neutralization for cancer immunotherapy., PMID:40425444

Enhancing H11 Protein-Induced Immune Protection Against Haemonchus contortus in Goats: A Nano-Adjuvant Formulation Strategy., PMID:40427752

Immunogenicity of an Intranasal Dual (Core and Surface)-Antigen Vaccine Against Hepatitis B Virus Enhanced by Carboxyl-Vinyl Polymer Excipients., PMID:40432076

Chlamydia muridarum mutant CM-pGP3S as a novel attenuated live rectal vaccine protects against genital tract infection., PMID:40433661

Prolonged effects of adenoviral vector priming on T-cell cytokine production in heterologous adenoviral vector/mRNA COVID-19 vaccination regimens., PMID:40436912

Differences in Aqueous Humor Cytokine Concentrations According to the Presence of Posterior Subcapsular Cataract: A Prospective Case-Control Study., PMID:40441712

Development of a Cell Membrane-Anchored Aptamer Sensor for IL-2 Detection In Situ., PMID:40447990

Chimeric antigen receptors discriminate between tau and distinct amyloid-beta species., PMID:40448101

T-cell activation enhances anti-HER2-mediated antibody-dependent cellular cytotoxicity in gastric cancer., PMID:40455140

The immunosuppressive effect of glucocorticoids in human primary T cells is mainly mediated via a rapid inhibition of the IL-2/IL-2R signaling axis., PMID:40468327

Advances of oncolytic vaccinia viruses armed with interleukin in tumor therapy., PMID:40469178

Spatially Tuned Localization of Interleukins and OX40 Agonists Enhances Synergistic Anti-Tumor Immunity., PMID:40475557

Optimizing delivery in a multivalent subunit influenza vaccine using mixed polymeric microparticle degradation rates., PMID:40482923

Anti-TNFR2 antibody and HMGN1 combined with TIL cell therapy inhibits colorectal cancer progression by enhancing immune response., PMID:40483876

IL-18 favors Th2 responses in sporotrichosis caused by Sporothrix globosa, prolonging the course of the disease., PMID:40489556

Expanded adaptive NKG2C+ NK cells exhibit potent ADCC and functional responses against HBV-infected hepatoma cell lines., PMID:40501566

Mechanistic investigation of calcium phosphate mineralization potentiating the cellular immune response of foot-and-mouth disease virus-like particle vaccines., PMID:40512119

Anti-melanoma differentiation-associated gene 5 antibody associated rapidly progressive interstitial lung disease in a pediatric patient: a case report., PMID:40514742

Effect of Metformin on vascular endothelial injury in patients with non-small cell lung cancer treated with chemotherapy combined with bevacizumab., PMID:40522519

In Vitro Culture for H5N1-Specific Duck T Cells and Detection of Immune Responses Using Intracellular Cytokine Staining Method., PMID:40522882

[Research on the inhibitory effects of evodiamine on activated T cell proliferation]., PMID:40525340

Immunogenicity of the Comirnaty Omicron XBB.1.5 booster COVID-19 mRNA vaccine in patients with cirrhosis., PMID:40525725

Oral administration of Lactiplantibacillus plantarum GKK1 ameliorates atopic dermatitis in a mouse model., PMID:40529585

Tumor-Associated NK Cells Regulate Distinct CD8+ T-cell Differentiation Program in Cancer and Contribute to Resistance against Immune Checkpoint Blockers., PMID:40530506

Datasheet
$ 370
Product specifications
100 μg 370 1 mg 1480 5 mg 4440

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Anti-Human IL2 (AU 007) [DHF36802]
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