Catalog No.
PHC04401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MMP1 (Phe20-Asn469).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
MMP1,MMP-1,Matrix metalloproteinase-1,CLG,Interstitial collagenase,Fibroblast collagenase
Purification
Purified by antigen affinity column.
Accession
P03956
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Antiphospholipid antibodies inhibit the migration and invasion of trophoblast cells by suppressing the JNK/C-Jun/MMP1 signaling pathway., PMID:40410845
MMP1-induced NF-κB activation promotes epithelial-mesenchymal transition and sacituzumab govitecan resistance in hormone receptor-positive breast cancer., PMID:40287412
Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors., PMID:39872437
Effectiveness and cytokine profile of combined anti-vascular endothelial growth factor and corticosteroid therapy for chronic retinal vein occlusion., PMID:39825912
Perfluoroalkyl substances (PFAS) exposure and preeclampsia risk: Impaired angiogenesis through suppression of VEGF signaling., PMID:39732411
SPHK1 promotes HNSCC immune evasion by regulating the MMP1-PD-L1 axis., PMID:39629135
Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma., PMID:39097197
Identifying hub genes in response to ustekinumab and the impact of ustekinumab treatment on fibrosis in Crohn's disease., PMID:38840917
Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck squamous cell carcinoma cells when cocultured in spheroids., PMID:38822309
A general approach for selection of epitope-directed binders to proteins., PMID:38683990
Characterization of immortalized ovarian epithelial cells with BRCA1/2 mutation., PMID:38615309
The Role of Matrix Metalloproteinases in Thoracic Aortic Disease: Are They Indicators for the Pathogenesis of Dissections?, PMID:38540232
An in vitro study elucidating the synergistic effects of aqueous cinnamon extract and an anti-TNF-α biotherapeutic: implications for a complementary and alternative therapy for non-responders., PMID:38521924
Protein kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines., PMID:38323010
Immunoreactivity of p21, MMP-1 and CB2 receptor proteins in cutaneous canine mast cell tumours: an association with the three-tier grading system., PMID:38130452
Neuropeptide Y, a potential marker for lupus, promotes lupus development., PMID:38006754
Prediction of anti-TNF therapy failure in ulcerative colitis patients by ensemble machine learning: A prospective study., PMID:37928018
Granzyme B promotes matrix metalloproteinase-1 (MMP-1) release from gingival fibroblasts in a PAR1- and Erk1/2-dependent manner: A novel role in periodontal inflammation., PMID:37873693
Effect of chimeric antigen receptor T cells against protease-activated receptor 1 for treating pancreatic cancer., PMID:37667257
Paraneoplastic or not? Sirtuin 2 in anti-N-methyl-d-aspartate receptor encephalitis., PMID:37483157
Using Proteome Microarray and Gene Expression Omnibus Database to Screen Tumour-Associated Antigens to Construct the Optimal Diagnostic Model of Oesophageal Squamous Cell Carcinoma., PMID:37433700
A decrease of mitochondrial ubiquitin ligase increases the secretion of matrix metalloproteinase-1 by dermal fibroblasts through the induction of ER stress., PMID:37337400
Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine-associated myocarditis., PMID:37146127
Skeletonema marinoi Extracts and Associated Carotenoid Fucoxanthin Downregulate Pro-Angiogenic Mediators on Prostate Cancer and Endothelial Cells., PMID:37048126
Terminal Complement Activation Is Induced by Factors Released from Endplate Tissue of Disc Degeneration Patients and Stimulates Expression of Catabolic Enzymes in Annulus Fibrosus Cells., PMID:36980228
Mirikizumab Regulates Genes Involved in Ulcerative Colitis Disease Activity and Anti-TNF Resistance: Results From a Phase 2 Study., PMID:36881820
Role of Matrix Metalloproteinases and Their Inhibitors in Locally Invasive Papillary Thyroid Cancer., PMID:36551933
[Morphogenetic and pathogenetic features of hypertrophic and keloid scars of the head and neck]., PMID:36469714
Tofacitinib Inhibits STAT Phosphorylation and Matrix Metalloproteinase-3, -9 and -13 Production by C28/I2 Human Juvenile Chondrocytes., PMID:36217356
Diosmin and Trolox Have Anti-Arthritic, Anti-Inflammatory and Antioxidant Potencies in Complete Freund's Adjuvant-Induced Arthritic Male Wistar Rats: Roles of NF-κB, iNOS, Nrf2 and MMPs., PMID:36139795
Atorvastatin attenuates NS1 (Non-structural protein-1) of dengue type-2 serotype-induced expressions of matrix metalloproteinases in HL-60 cells, differentiated to neutrophils: Implications for the immunopathogenesis of dengue viral disease., PMID:36108401
Prenatal exposure to nickel and atopic dermatitis at age 3 years: a birth cohort study with cytokine profiles., PMID:35841308
Umbilicaria esculenta Extract Exhibits Antiwrinkle Activity by Suppressing ErbB2 Phosphorylation., PMID:35834632
Human organ rejuvenation by VEGF-A: Lessons from the skin., PMID:35749494
Gardnerella vaginalis induces matrix metalloproteinases in the cervicovaginal epithelium through TLR-2 activation., PMID:35679790
Concentration of Serum Matrix Metalloproteinase-3 in Patients With Primary Biliary Cholangitis., PMID:35529854
Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients., PMID:35488348
Mechanotransductive Mechanisms of Biomimetic Hydrogel Cues Modulating Meckel's Cartilage Degeneration., PMID:35347898
Inhibitory effect of membrane‑free stem cell components derived from adipose tissues on skin inflammation in keratinocytes., PMID:35169867
Oral Cancer Theranostic Application of FeAu Bimetallic Nanoparticles Conjugated with MMP-1 Antibody., PMID:35010011
Clinical value of serum biomarkers, squamous cell carcinoma antigen and apolipoprotein C-II in follow-up of patients with locally advanced cervical squamous cell carcinoma treated with radiation: A multicenter prospective cohort study., PMID:34727105
TNFα blockade reverses vascular and uteroplacental matrix metalloproteinases imbalance and collagen accumulation in hypertensive pregnant rats., PMID:34600915
A serological type II collagen neoepitope biomarker reflects cartilage breakdown in patients with osteoarthritis., PMID:36474766
Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect., PMID:34147124
Label-free electrochemical immunosensor based on gold nanoparticle/polyethyleneimine/reduced graphene oxide nanocomposites for the ultrasensitive detection of cancer biomarker matrix metalloproteinase-1., PMID:34048512
Adalimumab Induces a Wound Healing Profile in Patients with Hidradenitis Suppurativa by Regulating Macrophage Differentiation and Matrix Metalloproteinase Expression., PMID:33965402
Extensive cytokine analysis in synovial fluid of osteoarthritis patients., PMID:33895075
MIN score predicts primary response to infliximab/adalimumab and vedolizumab therapy in patients with inflammatory bowel diseases., PMID:33872704
Ablation of CRBN induces loss of type I collagen and SCH in mouse skin by fibroblast senescence via the p38 MAPK pathway., PMID:33658395
Matrix metalloproteinases in the pathogenesis of dengue viral disease: Involvement of immune system and newer therapeutic strategies., PMID:33634515
For research use only. Not for human or drug use.
