Catalog No.
DHF71902
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Applications
Research Grade Biosimilar
Target
Putative liver tumor regressor, HEPC, LEAP-1, Liver-expressed antimicrobial peptide 1, PLTR, Hepcidin, LEAP1, Hepc25, Hepc20, HAMP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P81172
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
AN-LP1, AN LP1, ANLP1
Clone ID
AN-LP1
Note
For research use only. Not suitable for clinical or therapeutic use.
Hepcidin in human iron disorders: therapeutic implications., PMID:20932599
Iron overload induces BMP6 expression in the liver but not in the duodenum., PMID:20952515
A novel monoclonal antibody immunoassay for the detection of human serum hepcidin., PMID:21136275
Hepcidin and iron species distribution inside the first-trimester human gestational sac., PMID:21177636
The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease., PMID:21351217
Case report: branch retinal vein occlusion and primary antiphospholipid syndrome., PMID:21511536
[Effect of recombinant human erythropoietin on hepcidin mRNA expression in patients with multiple myeloma]., PMID:21518494
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice., PMID:21622652
Nuclear factor-κB mediated lipopolysaccharide-induced mRNA expression of hepcidin in human peripheral blood leukocytes., PMID:21685415
Modulation of the immune-related gene responses to protect mice against Japanese encephalitis virus using the antimicrobial peptide, tilapia hepcidin 1-5., PMID:21726898
Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats., PMID:21730356
Insights into the antibacterial and immunomodulatory functions of tilapia hepcidin (TH)2-3 against Vibrio vulnificus infection in mice., PMID:21756935
Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced by Helicobacter pylori infection., PMID:21757452
Effects of a single dose of oral iron on hepcidin concentrations in human urine and serum analyzed by a robust LC-MS/MS method., PMID:21867695
Recombinant medaka (Oryzias melastigmus) pro-hepcidin: Multifunctional characterization., PMID:22051539
Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis., PMID:22207682
[The effects and mechanisms of erythropoietin on hepcidin of human monocytes]., PMID:22213867
Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation., PMID:22290531
Inflammation-induced hepcidin is associated with the development of anemia and coronary artery lesions in Kawasaki disease., PMID:22392047
Increased hepcidin expression in multibacillary leprosy., PMID:23283470
Effects of subcutaneous and intravenous golimumab on inflammatory biomarkers in patients with rheumatoid arthritis: results of a phase 1, randomized, open-label trial., PMID:23418046
Allogeneic transplantation, Fas signaling, and dysregulation of hepcidin., PMID:23707854
IL-22 regulates iron availability in vivo through the induction of hepcidin., PMID:23836059
[Hemochromatosis: one form of iron-overload diseases]., PMID:23853349
Hepcidin plays a negative role in liver regeneration., PMID:24123375
Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway., PMID:24746831
Apoptosis induced by Fas signaling does not alter hepatic hepcidin expression., PMID:25225605
RAP-011, an activin receptor ligand trap, increases hemoglobin concentration in hepcidin transgenic mice., PMID:25236856
Expression and cellular localization of hepcidin mRNA and protein in normal rat brain., PMID:25896789
Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation., PMID:26635037
Disruption of Iron Regulation after Radiation and Donor Cell Infusion., PMID:27060441
Two routes of infection with Photobacterium damselae subsp. piscicida are effective in the modulation of the transcription of immune related genes in Solea senegalensis., PMID:27590420
Erythropoietin administration increases splenic erythroferrone protein content and liver TMPRSS6 protein content in rats., PMID:28282554
The dynamics of hepcidin-ferroportin internalization and consequences of a novel ferroportin disease mutation., PMID:28681497
β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids via Farnesoid X Receptor and Constitutive Androstane Receptor., PMID:30100908
The Hepcidin/Ferroportin axis modulates proliferation of pulmonary artery smooth muscle cells., PMID:30154413
Hepcidin mediated iron homoeostasis as immune regulator in visceral leishmaniasis patients., PMID:30402883
Targeting the hepcidin-ferroportin pathway in anaemia of chronic kidney disease., PMID:30677788
Evidence for dimerization of ferroportin in a human hepatic cell line using proximity ligation assays., PMID:32301493
Novel Insights Into the Effects of Interleukin 6 Antagonism in Non-ST-Segment-Elevation Myocardial Infarction Employing the SOMAscan Proteomics Platform., PMID:32515246
Atypical juvenile hereditary hemochromatosis onset with positive pancreatic islet autoantibodies diabetes caused by novel mutations in HAMP and overall clinical management., PMID:33016646
Immunoadsorption for heart failure is associated with normalization of iron metabolism., PMID:33843393
From the Cochrane Library: Systemic Treatments for Metastatic Cutaneous Melanoma., PMID:37632820
Selective CNS Targeting and Distribution with a Refined Region-Specific Intranasal Delivery Technique via the Olfactory Mucosa., PMID:34834319
Epstein-Barr Virus Infection Is Associated with Elevated Hepcidin Levels., PMID:36675141
Dupilumab-associated mycosis fungoides: a cross-sectional study., PMID:37270763
Myeloid cell iron uptake pathways and paramagnetic rim formation in multiple sclerosis., PMID:37715818
Dupilumab-Associated Sezary Syndrome., PMID:37822402
Bone marrow stromal cell-derived hepcidin has antimicrobial and immunomodulatory activities., PMID:38368463
Synthetic Antimicrobial Peptides Fail to Induce Leucocyte Innate Immune Functions but Elicit Opposing Transcriptomic Profiles in European Sea Bass and Gilthead Seabream., PMID:38393057
For research use only. Not for human or drug use.
