Research Grade Anti-Human GHR (DR10112)

Catalog No.

DHC84301

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

GHR, GH-binding protein, Growth hormone receptor, GHBP, Somatotropin receptor, GH receptor, Serum-binding protein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P10912

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

DR10112

Clone ID

DR10112

Lichenoid graft-versus-host disease shows a high interferon score, with IFNAR1 inhibition preventing skin inflammation., PMID:40439472

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference., PMID:40437880

Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial., PMID:40120616

A humanised ACE2, TMPRSS2, and FCGRT mouse model reveals the protective efficacy of anti-receptor binding domain antibodies elicited by SARS-CoV-2 hybrid immunity., PMID:40020261

Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial., PMID:39974075

The case for regulatory approval of amyloid-lowering immunotherapies in Alzheimer's disease based on clearcut biomarker evidence., PMID:39535341

Site-Selective Zwitterionic Poly(caprolactone-carboxybetaine)-Growth Hormone Receptor Antagonist Conjugate: Synthesis and Biological Evaluation., PMID:39471281

Influence of Th1 versus Th2 immune bias on viral, pathological, and immunological dynamics in SARS-CoV-2 variant-infected human ACE2 knock-in mice., PMID:39353281

Maximizing the Utility of Alzheimer's Disease Trial Data: Sharing of Baseline A4 and LEARN Data., PMID:39044498

Longitudinal Phospho-tau217 Predicts Amyloid Positron Emission Tomography in Asymptomatic Alzheimer's Disease., PMID:39044490

Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies., PMID:39044488

Pro Inflammatory Cytokines Profiles of Patients With Long COVID Differ Between Variant Epochs., PMID:38808863

Updated safety results from phase 3 lecanemab study in early Alzheimer's disease., PMID:38730496

Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU): Trial Satisfaction and Attitudes towards Future Clinical Trials., PMID:38706272

Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial., PMID:38683602

Current understanding of the Alzheimer's disease-associated microbiome and therapeutic strategies., PMID:38172602

Development and characterisation of a novel inhibitory anti-GH monoclonal antibody., PMID:37855323

Accelerating Alzheimer's therapeutic development: The past and future of clinical trials., PMID:37848035

Insulin-like Growth Factor 1, Growth Hormone, and Anti-Müllerian Hormone Receptors Are Differentially Expressed during GnRH Neuron Development., PMID:37685880

Lecanemab in patients with early Alzheimer's disease: detailed results on biomarker, cognitive, and clinical effects from the randomized and open-label extension of the phase 2 proof-of-concept study., PMID:36544184

The Future of AD Clinical Trials with the Advent of Anti-Amyloid Therapies: An CTAD Task Force Report., PMID:35841240

The Impact of Curcumin on Growth Performance, Growth-Related Gene Expression, Oxidative Stress, and Immunological Biomarkers in Broiler Chickens at Different Stocking Densities., PMID:35454205

Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study., PMID:35305339

Effect of Essential Oils on the Oxyntopeptic Cells and Somatostatin and Ghrelin Immunoreactive Cells in the European Sea Bass (Dicentrarchus labrax) Gastric Mucosa., PMID:34944178

The global Alzheimer's Association round robin study on plasma amyloid β methods., PMID:34692980

Platform Trials to Expedite Drug Development in Alzheimer's Disease: A Report from the EU/US CTAD Task Force., PMID:34101788

Preparation of a Growth Hormone Receptor/Prolactin Receptor Bispecific Antibody Antagonist Which Exhibited Anti-Cancer Activity., PMID:33362552

Antiphospholipid antibodies in patients with coronavirus disease 2019 infection hospitalized in conventional unit., PMID:33273262

Short-term Psychological Outcomes of Disclosing Amyloid Imaging Results to Research Participants Who Do Not Have Cognitive Impairment., PMID:32777010

Rational Design of Hypoallergenic Vaccines: Blocking IgE-binding to Polcalcin Using Allergen-specific IgG Antibodies., PMID:32615661

[Effects of brain necroptosis and cytokines expression array on brain injury in rats with cardiac arrest]., PMID:32527358

Transcriptomic Analysis of Spleen Revealed Mechanism of Dexamethasone-Induced Immune Suppression in Chicks., PMID:32384708

Autocrine/paracrine actions of growth hormone in human melanoma cell lines., PMID:31890904

Gantenerumab reduces amyloid-β plaques in patients with prodromal to moderate Alzheimer's disease: a PET substudy interim analysis., PMID:31831056

Early Detection of Growth Hormone Secretagogue Receptor Antagonists Exploiting Their Atypical Behavior in Competitive Assays., PMID:31702907

Epitope-based immunoinformatics study of a novel Hla-MntC-SACOL0723 fusion protein from Staphylococcus aureus: Induction of multi-pattern immune responses., PMID:31351414

Protodomains: Symmetry-Related Supersecondary Structures in Proteins and Self-Complementarity., PMID:30945220

Serum biomarker panels for the diagnosis of gastric cancer., PMID:30873760

Fructose-induced metabolic disturbances in rats and its impact on stomach endocrine cell number and smooth muscle contractility., PMID:30633582

Xenogeneic transplantation and tolerance in the era of CRISPR-Cas9., PMID:30480643

Induction of Apoptosis in Pterygium Cells by Antagonists of Growth Hormone-Releasing Hormone Receptors., PMID:30357400

Expression of growth hormone gene in the baboon eye., PMID:29407222

Subdomain 2, Not the Transmembrane Domain, Determines the Dimerization Partner of Growth Hormone Receptor and Prolactin Receptor., PMID:28977606

Targeting growth hormone receptor in human melanoma cells attenuates tumor progression and epithelial mesenchymal transition via suppression of multiple oncogenic pathways., PMID:28223541

Therapeutic effect of human ghrelin and growth hormone: Attenuation of immunosuppression in septic aged rats., PMID:28115288

Epidermal growth factor receptor (EGFR) involvement in successful growth hormone (GH) signaling in GH transduction defect., PMID:28099130

Growth hormone reverses excitotoxic damage induced by kainic acid in the green iguana neuroretina., PMID:27064058

Preparation and Characterization of an Antibody Antagonist That Targets the Porcine Growth Hormone Receptor., PMID:26954133

Role of abnormal anterior pituitary hormones-growth hormone and prolactin in active systemic lupus erythematosus., PMID:26770558

[Castleman's disease: Rapid desensitization for hypersensitivity reaction to rituximab]., PMID:26415921

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