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Anti-Human ABL1/p150 Antibody (SAA0785)

Catalog #:   RHB86801 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: Blocking, ELISA
Accession: P00519
Overview

Catalog No.

RHB86801

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Target

ABL, Proto-oncogene c-Abl, Abelson tyrosine-protein kinase 1, p150, JTK7, Abelson murine leukemia viral oncogene homolog 1, ABL1, Tyrosine-protein kinase ABL1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P00519

Applications

Blocking, ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0785

Data Image
References

Differentiation-dependent EBF1 Activity Determines CD22 Transcription and Leukemia Sensitivity to Inotuzumab Ozogamicin., PMID:40435412

Adult Acute Lymphoblastic Leukemia: 2025 Update on Diagnosis, Therapy, and Monitoring., PMID:40377367

Molecular characterization and predictors of relapse in patients with Ph + ALL after frontline ponatinib and blinatumomab., PMID:40369607

The evolving therapeutic revolution in adult acute lymphoblastic leukemia., PMID:40323723

Management of Adult Acute Lymphoblastic Leukemia: A Review., PMID:40310617

O-Cyanobenzaldehydes Irreversibly Modify Both Buried and Exposed Lysine Residues in Live Cells., PMID:40150802

Up-front blinatumomab improves MRD clearance and outcome in adult Ph- B-lineage ALL: the GIMEMA LAL2317 phase 2 study., PMID:40009490

Clearing MRD positivity with blinatumomab in pediatric B-cell acute lymphoblastic leukemia: insights from droplet digital PCR and flow cytometry., PMID:39668199

Philadelphia chromosome-positive or Philadelphia chromosome-like B-cell precursor acute lymphoblastic leukemia with multilineage involvement in pediatric patients: a report of two cases and literature review., PMID:39470068

SOHO State of the Art Updates and Next Questions | Approach to BCR::ABL1-Like Acute Lymphoblastic Leukemia., PMID:39217000

Blinatumomab for MRD-Negative Acute Lymphoblastic Leukemia in Adults., PMID:39047240

The BCR::ABL1 tyrosine kinase inhibitors ponatinib and nilotinib differentially affect endothelial angiogenesis and signalling., PMID:39009935

Asciminib stands out as the superior tyrosine kinase inhibitor to combine with anti-CD20 monoclonal antibodies for the treatment of CD20+ Philadelphia-positive B-cell precursor acute lymphoblastic leukemia in preclinical models., PMID:38841802

A Multicentre, Randomized Trial in Adults with de novo Philadelphia Chromosome-Positive Acute Lymphoblastic Leukaemia to Assess the Efficacy of Ponatinib versus Imatinib in Combination with Low-Intensity Chemotherapy, to Compare End of Therapy with Indication for Stem Cell Transplantation versus Tyrosine Kinase Inhibitor, Blinatumomab, and Chemotherapy in Optimal Responders, and to Evaluate Blinatumomab in Suboptimal Responders (GMALL-EVOLVE)., PMID:38754400

Asciminib Maintains Antibody-Dependent Cellular Cytotoxicity against Leukemic Blasts., PMID:38610966

Association of leukemic molecular profile with efficacy of inotuzumab ozogamicin in adults with relapsed/refractory ALL., PMID:38607410

A review of immunotargeted therapy for Philadelphia chromosome positive acute lymphoblastic leukaemia: making progress in chemotherapy-free regimens., PMID:38581291

Involvement of BCR::ABL1 in laminin adhesion of Philadelphia chromosome-positive  acute lymphoblastic leukemia through upregulation of integrin α6., PMID:38577721

[Successful treatment with sequential blinatumomab/ponatinib in a patient with chronic myeloid leukemia presenting with a CD19-positive mixed phenotype blast phase]., PMID:39935224

How to Manage Philadelphia-Positive Acute Lymphoblastic Leukemia in Resource-Constrained Settings., PMID:38136329

Long-Term Results of the Dasatinib-Blinatumomab Protocol for Adult Philadelphia-Positive ALL., PMID:38127722

Recent advances in therapies for primary myelofibrosis., PMID:37771602

Ph-like acute lymphoblastic leukemia in adults: understanding pathogenesis, improving outcomes, and future directions for therapy., PMID:37021793

Using immunotherapy and novel trial designs to optimise front-line therapy in adult acute lymphoblastic leukaemia: breaking with the traditions of the past., PMID:37003279

Prognostic value of cross-lineage expression of the myeloid-associated antigens CD13 and CD33 in adult B-lymphoblastic leukemia: A large real-world study of 1005 patients., PMID:36951610

The evolution of acute lymphoblastic leukemia research and therapy at MD Anderson over four decades., PMID:36927623

Computational approaches for discovering significant microRNAs, microRNA-mRNA regulatory pathways, and therapeutic protein targets in endometrial cancer., PMID:36704357

Identification of CD203c as a New Basophil-Specific Flow-Marker in Ph+ Chronic Myeloid Leukemia., PMID:36611797

Ph+ ALL in 2022: is there an optimal approach?, PMID:36485090

Profiling of extracellular vesicles of metastatic urothelial cancer patients to discover protein signatures related to treatment outcome., PMID:35838333

Molecular Classification and Overcoming Therapy Resistance for Acute Myeloid Leukemia with Adverse Genetic Factors., PMID:35682627

Measurable residual disease analysis in paediatric acute lymphoblastic leukaemia patients with ABL-class fusions., PMID:35650277

BCR::ABL1 tyrosine kinase inhibitors hamper the therapeutic efficacy of blinatumomab in vitro., PMID:35551463

Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement., PMID:35484682

Anti-N-methyl-D-aspartate receptor encephalitis associated with chronic myelogenous leukemia, causality or coincidence? A case report., PMID:35461209

Addition of four doses of rituximab to standard induction chemotherapy in adult patients with precursor B-cell acute lymphoblastic leukaemia (UKALL14): a phase 3, multicentre, randomised controlled trial., PMID:35358441

Identification of peripheral blood CD26+ leukemic stem cells has a potential role in the rapid diagnosis of chronic myeloid leukemia., PMID:35142061

The cure of leukemia through the optimist's prism., PMID:34614211

[B cell acute lymphoblastic leukemia therapy: an up to date overview]., PMID:34497196

Report of Canonical BCR-ABL1 Fusion in Glioblastoma., PMID:34485806

Comparison of Two Quantitative PCR-Based Assays for Detection of Minimal Residual Disease in B-Precursor Acute Lymphoblastic Leukemia Harboring Three Major Fusion Transcripts., PMID:34325057

Optimizing the treatment of acute lymphoblastic leukemia in younger and older adults: new drugs and evolving paradigms., PMID:34172894

Genetic Alterations and Therapeutic Targeting of Philadelphia-Like Acute Lymphoblastic Leukemia., PMID:34062932

Predictive value of tyrosine phosphatase receptor gamma for the response to treatment tyrosine kinase inhibitors in chronic myeloid leukemia patients., PMID:33893334

Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan., PMID:33707599

PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis., PMID:33531346

Protein Tyrosine Kinases: Their Roles and Their Targeting in Leukemia., PMID:33430292

Quantitative Tyrosine Phosphoproteomic Analysis of Resistance to Radiotherapy in Nasopharyngeal Carcinoma Cells., PMID:33328764

New approaches to the treatment of older adults with acute lymphoblastic leukemia., PMID:33256901

[Treatments for Philadelphia chromosome-positive acute lymphoblastic leukemia in the tyrosine kinase inhibitor era]., PMID:33162520

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-Human ABL1/p150 Antibody (SAA0785) [RHB86801]
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