Catalog No.
RHC13902
Species reactivity
Human, Pig
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Applications
ELISA, Neutralization, WB
Target
PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05121
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
8H9D4
Note
For research use only.
[The role of inherited thrombophilia and undifferentiated connective tissue dysplasia syndrome in the pathogenesis of female infertility: A clinical and morphological study]., PMID:26485774
Plasminogen Activation System in Rectal Adenocarcinoma., PMID:26504024
Testosterone Therapy Can Interact With Thrombophilia, Leading to Osteonecrosis., PMID:26652327
[[Gender Differences in Tissue Cascade of Activation of Plasminogen and PAI-1 in Esophageal Squamous Cell Carcinoma].]., PMID:28614640
Docosahexaenoic acid prevented tumor necrosis factor alpha-induced endothelial dysfunction and senescence., PMID:26802937
Increased Umbilical Cord PAI-1 Levels in Placental Insufficiency Are Associated with Fetal Hypoxia and Angiogenesis., PMID:26903689
Variant alleles in factor V, prothrombin, plasminogen activator inhibitor-1, methylenetetrahydrofolate reductase and risk of thromboembolism in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab., PMID:27001121
Associations of serum anti-ganglioside antibodies and inflammatory markers in diabetic peripheral neuropathy., PMID:27242125
FOSB is a Useful Diagnostic Marker for Pseudomyogenic Hemangioendothelioma., PMID:28009608
Fibrinolysis inhibitors in plaque stability: a morphological association of PAI-1 and TAFI in advanced carotid plaque., PMID:28135035
Polymorphism 4G/5G of the plasminogen activator inhibitor 1 gene as a risk factor for the development of allergic rhinitis symptoms in patients with asthma., PMID:28258374
Plasminogen activator inhibitor-1 regulates macrophage-dependent postoperative adhesion by enhancing EGF-HER1 signaling in mice., PMID:28270519
Potential biomarkers as an indicator of vertical transmission of Johne's disease in a Korean native cattle farm., PMID:28385000
The Evolving Interplay among Abundant Adipokines in Patients with Hepatitis C during Viral Clearance., PMID:28574439
CLINICAL AND GENETIC PECULIARITIES OF VASCULAR MANIFESTATIONS OF ANTIPHOSPHOLIPID SYNDROME (CASE REPORT)., PMID:28726667
Amplified endogenous plasmin activity resolves acute thrombotic thrombocytopenic purpura in mice., PMID:28981198
Skin Gene Expression Is Prognostic for the Trajectory of Skin Disease in Patients With Diffuse Cutaneous Systemic Sclerosis., PMID:29858547
The prognostic and predictive significance of plasma type 1 plasminogen activator inhibitor and endoglin in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy., PMID:30880754
Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart., PMID:31723062
Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells., PMID:32001531
Angiogenic Potential of Tissue Engineered Cartilage From Human Mesenchymal Stem Cells Is Modulated by Indian Hedgehog and Serpin E1., PMID:32363188
Evaluation of Osteogenic/Cementogenic Modulating Potential of PAI-1 Transfected Media for Stem Cells., PMID:32603295
IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome., PMID:32826331
Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484., PMID:33540702
A Narrative Review on Plasminogen Activator Inhibitor-1 and Its (Patho)Physiological Role: To Target or Not to Target?, PMID:33800359
Dysregulation of Pulmonary Responses in Severe COVID-19., PMID:34064104
Novel DNA methylation markers of PRRSV-specific antibodies and their intergenerational transmission from pregnant sows to piglets., PMID:34274485
CD276 is an important player in macrophage recruitment into the tumor and an upstream regulator for PAI-1., PMID:34290311
Serum anti-SERPINE1 antibody as a potential biomarker of acute cerebral infarction., PMID:34741085
Wnt5a/β-catenin axis is involved in the downregulation of AT2 lineage by PAI-1., PMID:36098461
Case-only design identifies interactions of genetic risk variants at SIGLEC5 and PLG with the lncRNA CTD-2353F22.1 implying the importance of periodontal wound healing for disease aetiology., PMID:36129033
Complement system-related genes in stomach adenocarcinoma: Prognostic signature, immune landscape, and drug resistance., PMID:36159981
Diagnosis and treatment of acquired factor VIII deficiency: a case report and literature review., PMID:36281058
Activin A directly impairs human cardiomyocyte contractile function indicating a potential role in heart failure development., PMID:36440002
Selective inhibition of HDAC6 promotes bladder cancer radiosensitization and mitigates the radiation-induced CXCL1 signalling., PMID:36810912
Continuous Administration of Anti-VEGFA Antibody Upregulates PAI-1 Secretion from Ovarian Cancer Cells via miR-143-3p Downregulation., PMID:37327051
Cancer-associated fibroblast-derived PAI-1 promotes lymphatic metastasis via the induction of EndoMT in lymphatic endothelial cells., PMID:37415190
Utilizing PK and PD Biomarkers to Guide the First-in-Human Starting Dose Selection of MTBT1466A: A Novel Humanized Monoclonal Anti-TGFβ3 Antibody for the Treatment of Fibrotic Diseases., PMID:37429356
TGF-β Score based on Silico Analysis can Robustly Predict Prognosis and Immunological Characteristics in Lower-grade Glioma: The Evidence from Multicenter Studies., PMID:37718518
Genetic Polymorphisms of GP1BA, PEAR1, and PAI-1 may be Associated with Serum sIgE and Blood Eosinophil Levels in Chinese Patients with Allergic Diseases., PMID:38299390
Plasma proteomic profiling reveals that SERPINE1 is a potential biomarker associated with coronary artery lesions in Kawasaki disease., PMID:39029232
In vitro neutralization of IL-6 receptor exacerbates damage to intestinal epithelial cells during Mycobacterium avium paratuberculosis infection., PMID:39170608
Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival., PMID:39232121
Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation., PMID:39923118
Senescence-related cytokine levels are associated with HIV-1 serostatus and persistence., PMID:39974095
IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury., PMID:40007559
Embryonic reprogramming of the tumor vasculature reveals targets for cancer therapy., PMID:40096611
Senescence-related cytokine levels are associated with HIV-1 serostatus and persistence., PMID:40202938
S-Adenosylmethionine Inhibits Plasminogen-Activating Inhibitor-1 and Protects Male Mice from FOLFOX-Induced Liver Injury., PMID:40246076
Tumor microenvironment modulation by SERPINE1 increases radioimmunotherapy in murine model of gastric cancer., PMID:40355586
For research use only. Not for human or drug use.
