Catalog No.
PHC00801
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human FN1 (Gly313-Ser607).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Cold-insoluble globulin, CIG, FN, Fibronectin, FN1
Concentration
0.64 mg/ml
Purification
Purified by antigen affinity column.
Accession
P02751
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice., PMID:40320111
Advancing pancreatic cancer therapy by mesothelin-specific nanobody conjugation., PMID:40275270
A novel serum protein biomarker for the late-stage diagnosis of nasopharyngeal carcinoma., PMID:40170144
Antibody-based delivery of interleukin-2 modulates the immunosuppressive tumor microenvironment and achieves cure in pancreatic ductal adenocarcinoma syngeneic mice., PMID:39773310
Streamlined on-column refolding and purification of nanobodies from inclusion bodies expressed as fusion proteins., PMID:39186888
A case of unexpected diagnosis of fibronectin glomerulopathy with histological features of membranoproliferative glomerulonephritis., PMID:38254040
RIPK3 Expression in Fibroblasts in an in vivo and in vitro Skin Wound Model: A Controversial Result., PMID:38234604
Autophagy activates EGR1 via MAPK/ERK to induce FGF2 in renal tubular cells for fibroblast activation and fibrosis during maladaptive kidney repair., PMID:37978868
Pathologic-genomic correlation identified a novel variant in FN1 and established the diagnosis of recurrent fibronectin glomerulopathy in the kidney allograft., PMID:37852577
Transcriptome analysis of renal ischemia/reperfusion (I/R) injury in BAFF and BAFF-R deficient mice., PMID:37751458
Identification of novel tumor-associated antigens and evaluation of a panel of autoantibodies in detecting oral cancer., PMID:37641028
Increased circulating fibronectin, depletion of natural IgM and heightened EBV, HSV-1 reactivation in ME/CFS and long COVID., PMID:37425897
Integrated analysis of circulating and tissue proteomes reveals that fibronectin 1 is a potential biomarker in papillary thyroid cancer., PMID:37158852
Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs., PMID:36806315
Chondrosarcoma with Target-Like Chondrocytes: Update on Molecular Profiling and Specific Morphological Features., PMID:36689318
Kawasaki Disease and Coronary Artery Involvement: A Narrative Review., PMID:36185934
FcεRI deficiency alleviates silica-induced pulmonary inflammation and fibrosis., PMID:36087468
A new mechanism of fibronectin fibril assembly revealed by live imaging and super-resolution microscopy., PMID:35851804
Modulation of diabetic kidney disease markers by an antagonist of p75NTR in streptozotocin-treated mice., PMID:35835402
Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis., PMID:35491858
Integrative system biology and mathematical modeling of genetic networks identifies shared biomarkers for obesity and diabetes., PMID:35240786
Pro-Resolving Factors Released by Macrophages After Efferocytosis Promote Mucosal Wound Healing in Inflammatory Bowel Disease., PMID:35003066
Neutrophil extracellular traps drive epithelial-mesenchymal transition of human colon cancer., PMID:34939675
High-resolution serum proteome trajectories in COVID-19 reveal patient-specific seroconversion., PMID:34232570
Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice., PMID:34089617
Elimination of cells deviated from human induced pluripotent stem cells with a photoactivatable IR700-labelled antibody., PMID:33774274
Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial-mesenchymal transition., PMID:33638284
Mutational and biophysical robustness in a prestabilized monobody., PMID:33617878
Identification of Potential BRAF Inhibitor Joint Therapy Targets in PTC based on WGCAN and DCGA., PMID:33613767
Leucine-rich Repeats and Immunoglobulin 1 (LRIG1) Ameliorates Liver Fibrosis and Hepatic Stellate Cell Activation via Inhibiting Sphingosine Kinase 1 (SphK1)/Sphingosine-1-Phosphate (S1P) Pathway., PMID:33463106
Nanostring-based screening for tyrosine kinase fusions in inflammatory myofibroblastic tumors., PMID:33127954
Noninvasive assessment and therapeutic monitoring of drug-resistant colorectal cancer by MR molecular imaging of extradomain-B fibronectin., PMID:33042274
Glycation of fibronectin inhibits VEGF-induced angiogenesis by uncoupling VEGF receptor-2-c-Src crosstalk., PMID:32613750
Human fibronectin extra domain B as a biomarker for targeted therapy in cancer., PMID:32386436
Non-cell autonomous promotion of astrogenesis at late embryonic stages by constitutive YAP activation., PMID:32341445
Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C., PMID:32312959
Secretome Analysis Performed During in vitro Cardiac Differentiation: Discovering the Cardiac Microenvironment., PMID:32117977
Evaluation of posterior capsule opacification of the Alcon Clareon IOL vs the Alcon Acrysof IOL using a human capsular bag model., PMID:32103739
Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression., PMID:31784980
Inhibition of the stem cell factor 248 isoform attenuates the development of pulmonary remodeling disease., PMID:31747308
Impact of AAV2 and Hepatitis B Virus Integration Into Genome on Development of Hepatocellular Carcinoma in Patients with Prior Hepatitis B Virus Infection., PMID:31320595
Stromal fibronectin expression in patients with resected pancreatic ductal adenocarcinoma., PMID:30736807
Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells., PMID:30716431
Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT., PMID:30573633
Methods for Investigating VLA-4 (CD49d/CD29) Expression and Activation in Chronic Lymphocytic Leukemia and Its Clinical Applications., PMID:30350200
The fibronectin ED-A domain enhances recruitment of latent TGF-β-binding protein-1 to the fibroblast matrix., PMID:29361522
NKp46 Receptor-Mediated Interferon-γ Production by Natural Killer Cells Increases Fibronectin 1 to Alter Tumor Architecture and Control Metastasis., PMID:29329948
Fibronectin glomerulopathy - A sporadic case with unusual clinical manifestation., PMID:29265057
Tumor-induced osteomalacia., PMID:29021995
Platelet-Derived Growth Factor Receptor α Contributes to Human Hepatic Stellate Cell Proliferation and Migration., PMID:28734947
For research use only. Not for human or drug use.
