Catalog No.
PHB97501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human COL2A1 (Ser1386-Pro1467).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
COL2A1,Collagen alpha-1(II) chain,Alpha-1 type II collagen
Purification
Purified by antigen affinity column.
Accession
P02458
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Hybrid Nanoparticle Engineered with Transforming Growth Factor -β1-Overexpressed Extracellular Vesicle and Cartilage-Targeted Anti-Inflammatory Liposome for Osteoarthritis., PMID:39648484
UBE2I regulates the nuclear translocation of hnRNPA2B1 by contributing to SUMO modification in osteoarthritis., PMID:38955308
A modified animal-free serum technique for efficient isolation and proliferation of mesenchymal stem cells from Hoffa fat pad., PMID:38158693
Biopolymer collagen-chitosan scaffold containing Aloe vera for chondrogenic efficacy on cartilage tissue engineering., PMID:37482169
Analysis of N-glycosylation protein of Kashin-Beck disease chondrocytes derived from induced pluripotent stem cells based on label-free strategies with LC-MS/MS., PMID:37186116
Individual immune cell and cytokine profiles determine platelet-rich plasma composition., PMID:36627721
Bevacizumab suppressed degenerative changes in articular cartilage explants from patients with osteoarthritis of the knee., PMID:36627659
Integrin β1, PDGFRβ, and type II collagen are essential for meniscus regeneration by synovial mesenchymal stem cells in rats., PMID:35986079
Proteomic Insight into the Role of Exosomes in Proliferative Vitreoretinopathy Development., PMID:35628842
Pathological differences in the bone healing processes between tooth extraction socket and femoral fracture., PMID:35372643
KLF4, negatively regulated by miR-7, suppresses osteoarthritis development via activating TGF-β1 signaling., PMID:34891002
Migratory chondroprogenitors retain superior intrinsic chondrogenic potential for regenerative cartilage repair as compared to human fibronectin derived chondroprogenitors., PMID:34880351
Different protective efficacies of a novel antigen-specific DNA vaccine encoding chicken type Ⅱ collagen via intramuscular, subcutaneous, and intravenous vaccination against experimental rheumatoid arthritis., PMID:34653764
Expression of nerve growth factor in the callus during fracture healing in a fracture model in aged mice., PMID:34487017
Characterisation and evaluation of the regenerative capacity of Stro-4+ enriched bone marrow mesenchymal stromal cells using bovine extracellular matrix hydrogel and a novel biocompatible melt electro-written medical-grade polycaprolactone scaffold., PMID:32251928
Early stage blockade of the alarmin HMGB1 reduces cartilage destruction in experimental OA., PMID:31982563
Enhanced chondrogenesis from human embryonic stem cells., PMID:31326745
Dual and Opposing Regulation of MMP1 and MMP13 by Both Arms of miR-675 in Human Articular Chondrocytes., PMID:31264811
Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway., PMID:30926814
Maintenance of SOX9 stability and ECM homeostasis by selenium-sensitive PRMT5 in cartilage., PMID:30858101
circRNA.33186 Contributes to the Pathogenesis of Osteoarthritis by Sponging miR-127-5p., PMID:30692016
Anti-inflammatory role of TPCA-1 encapsulated nanosomes in porcine chondrocytes against TNF-α stimulation., PMID:30600473
Effect of cellular mass on chondrogenic differentiation during embryoid body formation., PMID:30015965
Vaccination with a Novel Antigen-Specific Tolerizing DNA Vaccine Encoding CCOL2A1 Protects Rats from Experimental Rheumatoid Arthritis., PMID:29901407
Heparanase is expressed in adult human osteoarthritic cartilage and drives catabolic responses in primary chondrocytes., PMID:29803826
MicroRNA-193b-3p regulates chondrogenesis and chondrocyte metabolism by targeting HDAC3., PMID:29774080
Hyaluronic acid promotes proliferation and migration of human meniscus cells via a CD44-dependent mechanism., PMID:29658360
Isolation and characterization of buffalo (bubalus bubalis) amniotic mesenchymal stem cells derived from amnion from the first trimester pregnancy., PMID:29515060
Blockade of Interleukin 6 by Rat Anti-mouse Interleukin 6 Receptor Antibody Promotes Fracture Healing., PMID:29037140
Chondrogenic Pellet Formation from Cord Blood-derived Induced Pluripotent Stem Cells., PMID:28654049
Blockade of IL-17 alleviated inflammation in rat arthritis and MMP-13 expression., PMID:28617559
Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer., PMID:28396358
MicroRNA-92a-3p regulates the expression of cartilage-specific genes by directly targeting histone deacetylase 2 in chondrogenesis and degradation., PMID:27884646
Creating conditional dual fluorescence labeled transgenic animals for studying function of small noncoding RNAs., PMID:27763799
Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1β-Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte., PMID:27555113
Morphological, genetic and phenotypic comparison between human articular chondrocytes and cultured chondrocytes., PMID:27094849
Safety and immunogenicity of a novel therapeutic DNA vaccine encoding chicken type II collagen for rheumatoid arthritis in normal rats., PMID:26697972
The Wnt11 Signaling Pathway in Potential Cellular EMT and Osteochondral Differentiation Progression in Nephrolithiasis Formation., PMID:26193266
RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation., PMID:26025971
The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentiation., PMID:25451920
Calcitonin treatment is associated with less severe osteoarthritis and reduced toll-like receptor levels in a rat model., PMID:25146000
Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1., PMID:24997609
Can arthroscopically harvested synovial stem cells be preferentially sorted using stage-specific embryonic antigen 4 antibody for cartilage, bone, and adipose regeneration?, PMID:24581260
Characterization of a murine type IIB procollagen-specific antibody., PMID:24211541
Interleukin 6 mediates selected effects of Notch in chondrocytes., PMID:23954701
Structural variations in articular cartilage matrix are associated with early-onset osteoarthritis in the spondyloepiphyseal dysplasia congenita (sedc) mouse., PMID:23939426
Hmgb1 can facilitate activation of the matrilin-1 gene promoter by Sox9 and L-Sox5/Sox6 in early steps of chondrogenesis., PMID:23860260
Bidirectional and mutually beneficial interactions between human mesenchymal stem cells and osteoarthritic chondrocytes in micromass co-cultures., PMID:23627821
A reliable protocol for the isolation of viable, chondrogenically differentiated human mesenchymal stem cells from high-density pellet cultures., PMID:23514965
Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development., PMID:23319657
For research use only. Not for human or drug use.
