Catalog No.
FHF70410
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
C-C motif chemokine 7, MCP-3, CCL7, Monocyte chemotactic protein 3, Monocyte chemoattractant protein 3, NC28, Small-inducible cytokine A7, SCYA6, SCYA7, MCP3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P80098
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0539
IL-11/IL-11R signal inhibition by 9MW3811 remodels immune tumor microenvironment and enhances anti-tumor efficacy of PD-1 blockade., PMID:40355638
CCL7 promotes macrophage polarization and synovitis to exacerbate rheumatoid arthritis., PMID:40224025
C-C motif chemokines ligand 7 contributes to metabolic dysfunction-associated steatotic liver disease by enabling redox-sensitive induction of hypermethylated in cancer 1., PMID:40157597
The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer., PMID:39905201
Inhibition of CCL7 improves endothelial dysfunction and vasculopathy in mouse models of diabetes mellitus., PMID:39231238
Patient-specific vascularized tumor model: Blocking monocyte recruitment with multispecific antibodies targeting CCR2 and CSF-1R., PMID:39153324
Tumor-derived GLI1 promotes remodeling of the immune tumor microenvironment in melanoma., PMID:39090759
Rabies Virus Infection Causes Pyroptosis of Neuronal Cells., PMID:38891803
B cells mediate lung ischemia/reperfusion injury by recruiting classical monocytes via synergistic B cell receptor/TLR4 signaling., PMID:38488011
Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients., PMID:38196658
Patient-Specific Vascularized Tumor Model: Blocking TAM Recruitment with Multispecific Antibodies Targeting CCR2 and CSF-1R., PMID:38076998
Effects of leptin on the viability of human ovarian cancer cells and changes in cytokine expression levels., PMID:37155466
Anti-tumor effects of anti-programmed cell death-1 antibody treatment are attenuated in streptozotocin-induced diabetic mice., PMID:37046033
Fn-Dps, a novel virulence factor of Fusobacterium nucleatum, disrupts erythrocytes and promotes metastasis in colorectal cancer., PMID:36693067
Epitope Mapping of Anti-Mouse CCR3 Monoclonal Antibodies Using Flow Cytometry., PMID:36546900
CCL7 playing a dominant role in recruiting early OCPs to facilitate osteolysis at metastatic site of colorectal cancer., PMID:35715847
Immunosuppressive tumor microenvironment in uterine serous carcinoma via CCL7 signal with myeloid-derived suppressor cells., PMID:35353883
Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity., PMID:35314846
ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation., PMID:35218410
Neonatal LTβR signaling is required for the accumulation of eosinophils in the inflamed adult mesenteric lymph node., PMID:35181738
CC Chemokine Ligand 7 Derived from Cancer-Stimulated Macrophages Promotes Ovarian Cancer Cell Invasion., PMID:34206004
CCL7 contributes to angiotensin II-induced abdominal aortic aneurysm by promoting macrophage infiltration and pro-inflammatory phenotype., PMID:34189838
Predicting the allergenicity of legume proteins using a PBMC gene expression assay., PMID:33849432
Increased Stromal Infiltrating Lymphocytes Are Associated with the Risk of Disease Progression in Mesenchymal Circulating Tumor Cell-Positive Primary Breast Cancer Patients., PMID:33322711
CCL7 recruits cDC1 to promote antitumor immunity and facilitate checkpoint immunotherapy to non-small cell lung cancer., PMID:33257678
Longitudinal proteomic profiling reveals increased early inflammation and sustained apoptosis proteins in severe COVID-19., PMID:33239683
Verification of the role of exosomal microRNA in colorectal tumorigenesis using human colorectal cancer cell lines., PMID:33175885
Targeting Chemokines and Chemokine Receptors in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis., PMID:33061527
Anti-HER2 induced myeloid cell alterations correspond with increasing vascular maturation in a murine model of HER2+ breast cancer., PMID:32345237
Diagnostic Cytokines and Comparative Analysis Secreted from Exfoliated Deciduous Teeth, Dental Pulp, and Bone Marrow Derived Mesenchymal Stem Cells for Functional Cell-Based Therapy., PMID:31771293
CD8+ T cell/adipocyte inflammatory cross talk and ensuing M1 macrophage polarization are reduced by fish-oil-derived n-3 polyunsaturated fatty acids, in part by a TNF-α-dependent mechanism., PMID:31760229
Viral antigens elicit augmented immune responses in primary Sjögren's syndrome., PMID:31665501
Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis., PMID:31622668
Chemokine CCL7 regulates spinal phosphorylation of GluA1-containing AMPA receptor via interleukin-18 in remifentanil-induced hyperalgesia in rats., PMID:31430547
Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment., PMID:31320613
Chemokines CCL2 and CCL7, but not CCL12, play a significant role in the development of pain-related behavior and opioid-induced analgesia., PMID:31003094
Effect of Chemokine (C-C Motif) Ligand 7 (CCL7) and Its Receptor (CCR2) Expression on Colorectal Cancer Behaviors., PMID:30764543
Targeting RAGE as a potential therapeutic approach to Duchenne muscular dystrophy., PMID:30085099
Aggregates of IVIG or Avastin, but not HSA, modify the response to model innate immune response modulating impurities., PMID:30065306
An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium., PMID:28648867
The primary growth of laryngeal squamous cell carcinoma cells in vitro is effectively supported by paired cancer-associated fibroblasts alone., PMID:28475003
CCR3 Is Associated with the Death of a Photoreceptor Cell-line Induced by Light Exposure., PMID:28458639
Role of Interleukin-17A on the Chemotactic Responses to CCL7 in a Murine Allergic Rhinitis Model., PMID:28046055
Role of interferon-γ and inflammatory monocytes in driving colonic inflammation during acute Clostridium difficile infection in mice., PMID:27995603
Co-exposure to zymosan A and heat-inactivated Asian sand dust exacerbates ovalbumin-induced murine lung eosinophilia., PMID:27766108
Evidence for chemokine synergy during neutrophil migration in ARDS., PMID:27496101
Cancer-associated fibroblasts promote hepatocellular carcinoma metastasis through chemokine-activated hedgehog and TGF-β pathways., PMID:27216982
Induction of Monocyte Chemoattractant Proteins in Macrophages via the Production of Granulocyte/Macrophage Colony-Stimulating Factor by Breast Cancer Cells., PMID:26834744
Identification of a Novel Heart-Liver Axis: Matrix Metalloproteinase-2 Negatively Regulates Cardiac Secreted Phospholipase A2 to Modulate Lipid Metabolism and Inflammation in the Liver., PMID:26567374
Co-administration of antigen with chemokine MCP-3 or MDC/CCL22 enhances DNA vaccine potency., PMID:25952465
For research use only. Not for human or drug use.
