Anti-Human C3d Antibody (SAA0493)

Catalog No.

RHD25801

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

C3, ASP, Complement C3, C3adesArg, C3bc, CPAMD1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01024

Applications

ELISA, SPR, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0493

A multicenter prospective cohort study evaluating impact of an active delisting strategy to enable kidney transplantation in wait-listed candidates with calculated Panel Reactive Antibody ≥ 99.9., PMID:40484353

The 4 functional segments of Factor H: Role in physiological target recognition and contribution to disease., PMID:40356067

[Efficacy of iptacopan monotherapy for suboptimal response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria]., PMID:40237732

The treatment of autoimmune hemolytic anemia with complement inhibitor iptacopan: a case report., PMID:40115776

Distinguishing Neuromyelitis Optica Spectrum Disorders Subtypes: A Study on AQP4 and C3d Epitope Expression in Cytokine-Primed Human Astrocytes., PMID:40103346

The Generation of a H9N2 Avian Influenza Virus with HA and C3d-P29 Protein Fusions and Vaccine Development Applications., PMID:40006646

Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350., PMID:39909035

[83-year-old with angina pectoris, hemoglobinuria and icterus]., PMID:39879971

Potentiating CD20 monoclonal antibody therapy by targeting complement C3 fragments covalently deposited on lymphoma cells., PMID:39774793

Severe mycoplasma pneumoniae pneumonia combined with cold agglutinin disease and pulmonary embolism in childhood: A case report and review of the literature., PMID:39757967

Stay Away From the Cold: An Unusual Case of Cold Agglutinin Disease Presenting as Recurrent Transient Ischemic Attacks., PMID:39677145

The C3d-fused Porcine circovirus type 2d virus-like particle induced early and enhanced immune response and protected pigs against challenge., PMID:39536690

Interrogating post-transplant donor HLA-specific antibody characteristics and effector functions using clinical bead assays., PMID:39357467

IgG4 glycosylation contributes to the pathogenesis of IgG4 Hashimoto's thyroiditis via the complement pathway., PMID:39316722

Systemic Lupus Erythematosus Presenting With Cold-Antibody Autoimmune Hemolysis and Nephritis: A Case Report., PMID:39295688

Murine C3 of the complement system affects infection by Leptospira interrogans., PMID:39284496

Diagnosis of autoimmune bullous dermatoses: Comparative analysis of immunohistochemical staining using C4d, C3d, IgG, and IgG4 in lesional tissues and perilesional frozen skin samples., PMID:39180885

C4d, rather than C3d and C5b-9, Is Associated with Graft Loss in Recurrent IgA Deposition after Kidney Transplantation., PMID:39154645

Risk Stratification Before Living Donor Kidney Transplantation in Patients With Preformed Donor-specific Antibodies by Different Crossmatch Methods., PMID:39131238

[Cold agglutinin syndrome associated with infectious mononucleosis: A case report]., PMID:39116196

Characteristics of Early Antibody Mediated Rejection in Antibody Incompatible Living Donor Kidney Transplantation., PMID:39040870

Role of Natural Killer Cells in Antibody-mediated Rejection of Kidney Transplantation., PMID:38819183

Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management., PMID:38673882

A single-chain antibody construct with specificity of a natural IgM antibody reduces hepatic ischemia reperfusion injury in mice., PMID:38597412

Role of direct antiglobulin test in anemia under evaluation: Its prevalence, laboratory workup, and significance in further patient management-A study from eastern India., PMID:38563700

Challenging the dogma: Red blood cell-directed autoimmunity as risk factor for red blood cell alloimmunisation after blood transfusion., PMID:38494337

Direct immunofluorescence (DIF) versus immunohistochemical (IHC) staining of complements and immunoglobulins (Ig) in pemphigus group., PMID:38427745

C3d-Targeted factor H inhibits tissue complement in disease models and reduces glomerular injury without affecting circulating complement., PMID:38382529

Hemolytic anemia associated with intravenous immunoglobulin in Kawasaki disease., PMID:38245705

Concomitant presentation of thrombotic thrombocytopenic purpura, immune thrombocytopenia, and autoimmune hemolytic anemia in a patient with newly diagnosed systemic lupus erythematosus., PMID:38170038

C3d Immunohistochemical Staining on Paraffin-Embedded Tissue for Diagnosis of Pemphigus., PMID:38149406

Complement and Non-Complement Binding Anti-HLA Antibodies Are Differentially Detected with Different Antigen Bead Assays in Renal Transplant Recipients., PMID:38137802

Discovery and characterization of cross-reactive intrahepatic antibodies in severe alcoholic hepatitis., PMID:38055614

The Diagnostic Significance of C3d Antigen in Kidney and Skin Histopathology - The Current State-Of-The-Art and Practical Examples., PMID:37888966

Case report: Autoimmune hemolytic anemia caused by warm and cold autoantibodies with complement activation-etiological and therapeutic issues., PMID:37794962

Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA., PMID:37679571

The in vitro C3d generating attribute of HLA-specific antibodies can be used to stratify immune risk in HLA incompatible transplantation by predicting the clinical efficacy of desensitisation., PMID:37605347

Piperacillin-tazobactam induced immune hemolytic anemia led to increased renal impairment and eventual death from multiple organ failure in a patient with hypertensive nephropathy: case report and literature review., PMID:37316798

Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response., PMID:37283743

Complement C3d/C4d Deposition on Platelets Correlates with 2'-O-Methoxyethyl Antisense Oligonucleotide-Induced Thrombocytopenia in Monkeys., PMID:37093125

Noninvasive Detection of iC3b/C3d Deposits in the Kidney Using a Novel Bioluminescent Imaging Probe., PMID:36995143

Positive direct antiglobulin tests in cancer patients on immune checkpoint inhibitors: A case series from India., PMID:36931491

C1-inhibitor treatment in patients with severe complement-mediated autoimmune hemolytic anemia., PMID:36920779

Discovery and characterization of cross-reactive intrahepatic antibodies in severe alcoholic hepatitis., PMID:36865259

Anti-Neutrophil Extracellular Trap Antibodies in Antiphospholipid Antibody-Positive Patients: Results From the Antiphospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking Clinical Database and Repository., PMID:36862141

C3d-binding assay for the detection of complement activating HLA antibodies: A useful tool for allocation to highly sensitised recipients in the post-CDC era?, PMID:36851856

Three different pathways of IgM-antibody-dependent hemolysis are mainly regulated by complement., PMID:36817469

Cold antibody autoimmune hemolytic anemia following varicella infection., PMID:36656239

Anti-SARS-Cov-2 S-RBD IgG Formed after BNT162b2 Vaccination Can Bind C1q and Activate Complement., PMID:36573216

Prevalence of the Direct Antiglobulin Test and Its Clinical Impact on Multiply Transfused Thalassemia Patients: A Prospective Study Conducted at a Tertiary Care Center in Northern India., PMID:36495135

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