Anti-Human C3d Antibody (SAA0493)

Catalog No.

RHD25801

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Applications

ELISA, SPR, WB

Target

C3, ASP, Complement C3, C3adesArg, C3bc, CPAMD1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1

Concentration

0.73 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01024

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0493

Note

For research use only.

Prevalence of the Direct Antiglobulin Test and Its Clinical Impact on Multiply Transfused Thalassemia Patients: A Prospective Study Conducted at a Tertiary Care Center in Northern India., PMID:36495135

Anti-SARS-Cov-2 S-RBD IgG Formed after BNT162b2 Vaccination Can Bind C1q and Activate Complement., PMID:36573216

Cold antibody autoimmune hemolytic anemia following varicella infection., PMID:36656239

Three different pathways of IgM-antibody-dependent hemolysis are mainly regulated by complement., PMID:36817469

C3d-binding assay for the detection of complement activating HLA antibodies: A useful tool for allocation to highly sensitised recipients in the post-CDC era?, PMID:36851856

Anti-Neutrophil Extracellular Trap Antibodies in Antiphospholipid Antibody-Positive Patients: Results From the Antiphospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking Clinical Database and Repository., PMID:36862141

Discovery and characterization of cross-reactive intrahepatic antibodies in severe alcoholic hepatitis., PMID:36865259

C1-inhibitor treatment in patients with severe complement-mediated autoimmune hemolytic anemia., PMID:36920779

Positive direct antiglobulin tests in cancer patients on immune checkpoint inhibitors: A case series from India., PMID:36931491

Noninvasive Detection of iC3b/C3d Deposits in the Kidney Using a Novel Bioluminescent Imaging Probe., PMID:36995143

Complement C3d/C4d Deposition on Platelets Correlates with 2'-O-Methoxyethyl Antisense Oligonucleotide-Induced Thrombocytopenia in Monkeys., PMID:37093125

Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response., PMID:37283743

Piperacillin-tazobactam induced immune hemolytic anemia led to increased renal impairment and eventual death from multiple organ failure in a patient with hypertensive nephropathy: case report and literature review., PMID:37316798

The in vitro C3d generating attribute of HLA-specific antibodies can be used to stratify immune risk in HLA incompatible transplantation by predicting the clinical efficacy of desensitisation., PMID:37605347

Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA., PMID:37679571

Case report: Autoimmune hemolytic anemia caused by warm and cold autoantibodies with complement activation-etiological and therapeutic issues., PMID:37794962

The Diagnostic Significance of C3d Antigen in Kidney and Skin Histopathology - The Current State-Of-The-Art and Practical Examples., PMID:37888966

Discovery and characterization of cross-reactive intrahepatic antibodies in severe alcoholic hepatitis., PMID:38055614

Complement and Non-Complement Binding Anti-HLA Antibodies Are Differentially Detected with Different Antigen Bead Assays in Renal Transplant Recipients., PMID:38137802

C3d Immunohistochemical Staining on Paraffin-Embedded Tissue for Diagnosis of Pemphigus., PMID:38149406

Concomitant presentation of thrombotic thrombocytopenic purpura, immune thrombocytopenia, and autoimmune hemolytic anemia in a patient with newly diagnosed systemic lupus erythematosus., PMID:38170038

Hemolytic anemia associated with intravenous immunoglobulin in Kawasaki disease., PMID:38245705

C3d-Targeted factor H inhibits tissue complement in disease models and reduces glomerular injury without affecting circulating complement., PMID:38382529

Direct immunofluorescence (DIF) versus immunohistochemical (IHC) staining of complements and immunoglobulins (Ig) in pemphigus group., PMID:38427745

Challenging the dogma: Red blood cell-directed autoimmunity as risk factor for red blood cell alloimmunisation after blood transfusion., PMID:38494337

Role of direct antiglobulin test in anemia under evaluation: Its prevalence, laboratory workup, and significance in further patient management-A study from eastern India., PMID:38563700

A single-chain antibody construct with specificity of a natural IgM antibody reduces hepatic ischemia reperfusion injury in mice., PMID:38597412

Autoimmune Hemolytic Anemias: Classifications, Pathophysiology, Diagnoses and Management., PMID:38673882

Role of Natural Killer Cells in Antibody-mediated Rejection of Kidney Transplantation., PMID:38819183

Characteristics of Early Antibody Mediated Rejection in Antibody Incompatible Living Donor Kidney Transplantation., PMID:39040870

[Cold agglutinin syndrome associated with infectious mononucleosis: A case report]., PMID:39116196

Risk Stratification Before Living Donor Kidney Transplantation in Patients With Preformed Donor-specific Antibodies by Different Crossmatch Methods., PMID:39131238

C4d, rather than C3d and C5b-9, Is Associated with Graft Loss in Recurrent IgA Deposition after Kidney Transplantation., PMID:39154645

Diagnosis of autoimmune bullous dermatoses: Comparative analysis of immunohistochemical staining using C4d, C3d, IgG, and IgG4 in lesional tissues and perilesional frozen skin samples., PMID:39180885

Murine C3 of the complement system affects infection by Leptospira interrogans., PMID:39284496

Systemic Lupus Erythematosus Presenting With Cold-Antibody Autoimmune Hemolysis and Nephritis: A Case Report., PMID:39295688

IgG4 glycosylation contributes to the pathogenesis of IgG4 Hashimoto's thyroiditis via the complement pathway., PMID:39316722

Interrogating post-transplant donor HLA-specific antibody characteristics and effector functions using clinical bead assays., PMID:39357467

The C3d-fused Porcine circovirus type 2d virus-like particle induced early and enhanced immune response and protected pigs against challenge., PMID:39536690

Stay Away From the Cold: An Unusual Case of Cold Agglutinin Disease Presenting as Recurrent Transient Ischemic Attacks., PMID:39677145

Severe mycoplasma pneumoniae pneumonia combined with cold agglutinin disease and pulmonary embolism in childhood: A case report and review of the literature., PMID:39757967

Potentiating CD20 monoclonal antibody therapy by targeting complement C3 fragments covalently deposited on lymphoma cells., PMID:39774793

[83-year-old with angina pectoris, hemoglobinuria and icterus]., PMID:39879971

Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350., PMID:39909035

The Generation of a H9N2 Avian Influenza Virus with HA and C3d-P29 Protein Fusions and Vaccine Development Applications., PMID:40006646

Distinguishing Neuromyelitis Optica Spectrum Disorders Subtypes: A Study on AQP4 and C3d Epitope Expression in Cytokine-Primed Human Astrocytes., PMID:40103346

The treatment of autoimmune hemolytic anemia with complement inhibitor iptacopan: a case report., PMID:40115776

[Efficacy of iptacopan monotherapy for suboptimal response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria]., PMID:40237732

The 4 functional segments of Factor H: Role in physiological target recognition and contribution to disease., PMID:40356067

A multicenter prospective cohort study evaluating impact of an active delisting strategy to enable kidney transplantation in wait-listed candidates with calculated Panel Reactive Antibody ≥ 99.9., PMID:40484353

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