Catalog No.
FHF68010
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
Small-inducible cytokine D1, Fractalkine, Neurotactin, C-X3-C motif chemokine 1, NTT, CX3CL1, SCYD1, FKN, CX3C membrane-anchored chemokine
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P78423
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0469
CX3CR1+ Monocytes/Macrophages Promote Regional Immune Injury in Mesangial Proliferative Glomerulonephritis through Crosstalk with Activated Mesangial Cells., PMID:40458609
Metabolic-Immune Suppression Mediated by the SIRT1-CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma., PMID:39783838
Is modulation of immune checkpoints on glioblastoma-infiltrating myeloid cells a viable therapeutic strategy?, PMID:39427326
ITGB6 modulates resistance to anti-CD276 therapy in head and neck cancer by promoting PF4+ macrophage infiltration., PMID:39152118
Tumor-derived GLI1 promotes remodeling of the immune tumor microenvironment in melanoma., PMID:39090759
Clinical significance of circulating biomarkers of immune-checkpoint molecules with atezolizumab plus bevacizumab therapy in unresectable hepatocellular carcinoma., PMID:38963640
Expression and significance of Fractalkine/CX3CL1 in MPO-AAV-associated glomerulonephritis rats., PMID:38937701
Alirocumab boosts antioxidant status and halts inflammation in rat model of sepsis-induced nephrotoxicity via modulation of Nrf2/HO-1, PCSK9/HMGB1/NF-ᴋB/NLRP3 and Fractalkine/CX3CR1 hubs., PMID:38889644
The tumor-intrinsic role of the m6A reader YTHDF2 in regulating immune evasion., PMID:38820140
Chemokines and lymphocyte homing in Sjögren's syndrome., PMID:38736890
Diagnostic patterns of serum inflammatory protein markers in children with Lyme neuroborreliosis., PMID:38723400
Anti-CX3CL1 (fractalkine) monoclonal antibody attenuates lung and skin fibrosis in sclerodermatous graft-versus-host disease mouse model., PMID:38702742
Ocular surface immune transcriptome and tear cytokines in corneal infection patients., PMID:38694515
Mild Hypoxia Accelerates Cerebral Cavernous Malformation Disease Through CX3CR1-CX3CL1 Signaling., PMID:38660801
Chemokine expression in sera of patients with microscopic polyangiitis and granulomatosis with polyangiitis., PMID:38622321
Acid-sensing receptor GPR4 plays a crucial role in lymphatic cancer metastasis., PMID:38410865
Mucosal Immunity Related to CD8+ T Lymphocytes in Children with Helicobacter pylori Gastritis., PMID:38249639
Refined innate plasma signature after rVSVΔG-ZEBOV-GP immunization is shared among adult cohorts in Europe and North America., PMID:38235127
The Immune Signature of CSF in Multiple Sclerosis with and without Oligoclonal Bands: A Machine Learning Approach to Proximity Extension Assay Analysis., PMID:38203309
Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients., PMID:38196658
Biomarkers in the Pathogenesis, Diagnosis, and Treatment of Systemic Sclerosis., PMID:37868834
The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy., PMID:37771579
Virtual Screening of Protein Data Bank via Docking Simulation Identified the Role of Integrins in Growth Factor Signaling, the Allosteric Activation of Integrins, and P-Selectin as a New Integrin Ligand., PMID:37759488
Targeting Members of the Chemokine Family as a Novel Approach to Treating Neuropathic Pain., PMID:37570736
Immunogenicity and protective efficacy of an RSV G S177Q central conserved domain nanoparticle vaccine., PMID:37457705
Spinal Cathepsin S promotes visceral hypersensitivity via FKN/CX3CR1/p38 MAPK signaling pathways., PMID:37347150
CX3CL1 induces cell migration and invasion through ICAM-1 expression in oral squamous cell carcinoma cells., PMID:37082943
Effects of CX3CR1 and CXCR2 antagonists on running-dependent intramuscular neutrophil recruitments and myokine upregulation., PMID:36856190
Mesenchymal stem cells elicits Anti-PD1 immunotherapy by targeted delivery of CX3CL1., PMID:36843945
Systems biological assessment of the temporal dynamics of immunity to a viral infection in the first weeks and months of life., PMID:36778389
Characterising the autoantibody repertoire in systemic sclerosis following myeloablative haematopoietic stem cell transplantation., PMID:36653124
IL-1β promotes osteoclastogenesis by increasing the expression of IGF2 and chemokines in non-osteoclastic cells., PMID:36522118
Visualization of macrophage subsets in the development of the fetal human inner ear., PMID:36159857
FKN/NR Signaling Pathway Regulates Hippocampal Inflammatory Responses: the Survival of Hippocampal Neurons in Diabetic Rats with Chronic Unpredictable Mild Stress., PMID:36072409
CX3CL1-induced CD16+ monocytes extravasation in myeloperoxidase-ANCA-associated vasculitis correlates with renal damage., PMID:36059489
Neuroinflammation in the anterior cingulate cortex: the potential supraspinal mechanism underlying the mirror-image pain following motor fiber injury., PMID:35725625
Crosstalk between IL-15Rα+ tumor-associated macrophages and breast cancer cells reduces CD8+ T cell recruitment., PMID:35615815
CX3CL1 Worsens Cardiorenal Dysfunction and Serves as a Therapeutic Target of Canagliflozin for Cardiorenal Syndrome., PMID:35370759
Blockage of CX3CL1 Attenuates Platelet and Leukocyte Recruitment in Murine Hepatic I/R., PMID:35279656
Role of Fractalkine-CX3CR1 Axis in Acute Rejection of Mouse Heart Allografts Subjected to Ischemia Reperfusion Injury., PMID:35185378
T helper cells expressing fractalkine receptor and bearing T follicular helper 1-like cell functions in patients with IgG4-related disease., PMID:34940835
Distribution of Immune Cells Including Macrophages in the Human Cochlea., PMID:34880828
Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players., PMID:34864314
Ex vivo treatment of cytomegalovirus in human donor lungs using a novel chemokine-based immunotoxin., PMID:34802874
CCR2- and CCR5-mediated macrophage infiltration contributes to glomerular endocapillary hypercellularity in antibody-induced lupus nephritis., PMID:34747459
Urinary IgG, serum CX3CL1 and miRNA-152-3p: as predictors of nephropathy in Egyptian type 2 diabetic patients., PMID:34689723
CX3CL1(+) Microparticles-Induced MFG-E8 Enhances Apoptotic Cell Clearance by Alveolar Macrophages., PMID:34685562
The Entry and Egress of Monocytes in Atherosclerosis: A Biochemical and Biomechanical Driven Process., PMID:34345249
Selective targeting of ligand-dependent and -independent signaling by GPCR conformation-specific anti-US28 intrabodies., PMID:34272386
Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2., PMID:34223817
For research use only. Not for human or drug use.
