Catalog No.
FHC40010
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
CXCL1, GROA, GRO1, Neutrophil-activating protein 3, GRO, C-X-C motif chemokine 1, NAP-3, Growth-regulated alpha protein, MGSA, SCYB1, Melanoma growth stimulatory activity, GRO-alpha(1-73)
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P09341
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0462
USP48 protects against myocardial ischemia-reperfusion injury by stabilizing and upregulating CNN1 in type 1 diabetes mice., PMID:40513941
Modulating the CXCR2 Signaling Axis Using Engineered Chemokine Fusion Proteins to Disrupt Myeloid Cell Infiltration in Pancreatic Cancer., PMID:40427538
The CXCL1-CXCR2 Axis as a Component of Therapy Resistance, a Source of Side Effects in Cancer Treatment, and a Therapeutic Target., PMID:40427171
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma., PMID:40374617
Immunodynamic axis of fibroblast-driven neutrophil infiltration in acute pancreatitis: NF-κB-HIF-1α-CXCL1., PMID:40335899
NAT10 exacerbates acute renal inflammation by enhancing N4-acetylcytidine modification of the CCL2/CXCL1 axis., PMID:40261924
Bifunctional chemokine-nanobody fusion protein enhances neutrophil recruitment to impede Acanthamoeba immune evasion., PMID:40222104
Potential role of liver-resident CD3+ macrophages in HBV clearance in a mouse hepatitis B model., PMID:40143948
Long-term nucleus basalis cholinergic lesions alter the structure of cortical vasculature, astrocytic density and microglial activity in Wistar rats., PMID:40121723
Microglial repopulation alleviates surgery-induced neuroinflammation and cognitive impairment in a ZEB1-dependent manner., PMID:40052833
Immunological biomarkers of response and resistance to treatment with cabozantinib and nivolumab in recurrent endometrial cancer., PMID:40010771
Neutrophil extracellular traps impede cancer metastatic seeding via protease-activated receptor 2-mediated downregulation of phagocytic checkpoint CD24., PMID:40010762
Lung-delivered IL-10 mitigates Lung inflammation induced by repeated endotoxin exposures in male mice., PMID:39980189
Coactivation of innate immune suppressive cells induces acquired resistance against combined TLR agonism and PD-1 blockade., PMID:39937883
Effectiveness and cytokine profile of combined anti-vascular endothelial growth factor and corticosteroid therapy for chronic retinal vein occlusion., PMID:39825912
Group B Streptococcal Membrane Vesicles Induce Proinflammatory Cytokine Production and Are Sensed in an NLRP3 Inflammasome-Dependent Mechanism in a Human Macrophage-like Cell Line., PMID:39761308
[Protective effect of Streptococcus salivarius K12 against Mycoplasma pneumoniae infection in mice]., PMID:39725618
Anti-Atopic Dermatitis Effect of Azalomycin F on 2,4-Dinitrofluorobenzene-Induced Mice and Potential Mechanism., PMID:39684557
Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) drives abnormal pericyte-rich vasculature in triple-negative breast cancer., PMID:39636369
CXCL1-CXCR2 signaling mediates the activation of microglia in the nucleus tractus solitarii to promote pancreatic cancer-induced pain., PMID:39528100
Investigating the impact of tocilizumab on serum cytokines concentrations in Japanese FMF patients: a sub-analysis of the NUH01FMF study., PMID:39440870
TGFβ1-TNFα regulated secretion of neutrophil chemokines is independent of epithelial-mesenchymal transitions in breast tumor cells., PMID:39416223
Deciphering the mechanisms of the IL-6/CXCL1 and NOD-like receptor signaling pathways in otitis media with effusion in rodents., PMID:39293312
In vitro analysis of VEGF-mediated endothelial permeability and the potential therapeutic role of Anti-VEGF in severe dengue., PMID:39263317
Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival., PMID:39232121
Oral administration of Lactobacillus delbrueckii UFV-H2b20 protects mice against Aspergillus fumigatus lung infection., PMID:39198294
Alternating electric fields transform the intricate network of tumour vasculature into orderly parallel capillaries and enhance the anti-angiogenesis effect of bevacizumab., PMID:39161078
The oncogenic kinase TOPK upregulates in psoriatic keratinocytes and contributes to psoriasis progression by regulating neutrophils infiltration., PMID:39090602
Spesolimab Reduces Inflammation in Generalized Pustular Psoriasis: Molecular Characterization of Flare Treatment in EFFISAYIL 1., PMID:39004117
Anti-CTLA-4 m2a Antibody Exacerbates Cardiac Injury in Experimental Autoimmune Myocarditis Mice By Promoting Ccl5-Neutrophil Infiltration., PMID:38978328
Clinical significance of circulating biomarkers of immune-checkpoint molecules with atezolizumab plus bevacizumab therapy in unresectable hepatocellular carcinoma., PMID:38963640
Inflammatory Profiles Induced by Intranasal Immunization with Ricin Toxin-immune Complexes., PMID:38922287
Discovery and preclinical evaluation of KYS202004A, a novel bispecific fusion protein targeting TNF-α and IL-17A, in autoimmune disease models., PMID:38843642
Enhanced amphiregulin exposure promotes modulation of the high grade serous ovarian cancer tumor immune microenvironment., PMID:38831884
Inhibition of interferon gamma impairs induction of experimental epidermolysis bullosa acquisita., PMID:38799441
CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1-CXCR2 induced NETs., PMID:38724465
Chemokine expression in sera of patients with microscopic polyangiitis and granulomatosis with polyangiitis., PMID:38622321
Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation., PMID:38563353
Circular RNA circNCOA3 promotes tumor progression and anti-PD-1 resistance in colorectal cancer., PMID:38510750
Differential anti-viral response to respiratory syncytial virus A in preterm and term infants., PMID:38447274
Neutrophil-Associated Proteins as Novel Biomarkers Elevated in Cerebrospinal Fluid of Patients With Neurosyphilis., PMID:38427829
TNFα: TNFR1 signaling inhibits maturation and maintains the pro-inflammatory programming of monocyte-derived macrophages in murine chronic granulomatous disease., PMID:38404573
Neutrophils are indispensable for adverse cardiac remodeling in heart failure., PMID:38387309
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2., PMID:38267628
The Role and Mechanism of Spinal NF-κB-CXCL1/CXCR2 in Rats with Nucleus Pulposus-induced Radicular Pain., PMID:38098294
Differential cellular immune responses against Orientia tsutsugamushi Karp and Gilliam strains following acute infection in mice., PMID:38091346
Involvement of CXC chemokines (CXCL1-CXCL17) in gastric cancer: Prognosis and therapeutic molecules., PMID:37995936
Tumor cell SPTBN1 inhibits M2 polarization of macrophages by suppressing CXCL1 expression., PMID:37921259
Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth., PMID:37776858
Catecholamines Promote Ovarian Cancer Progression through Secretion of CXC-Chemokines., PMID:37762405
For research use only. Not for human or drug use.
