Catalog No.
FHA04010
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
MPIF2, Eosinophil chemotactic protein 2, Small-inducible cytokine A24, CCL24, Eotaxin-2, SCYA24, MPIF-2, Myeloid progenitor inhibitory factor 2, CK-beta-6, C-C motif chemokine 24
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O00175
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0461
Depletion of eosinophils during sensitization but not challenge phase in mice blocks the development of food allergy early in life., PMID:40073088
Stress-experienced monocytes/macrophages lose anti-inflammatory function via β2-adrenergic receptor in skin allergic inflammation., PMID:39566608
Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma., PMID:39097197
Macrophage activation and inflammatory priming by anti-MAA antibodies in rheumatoid arthritis., PMID:38969267
Targeting CCL24 in Inflammatory and Fibrotic Diseases: Rationale and Results from Three CM-101 Phase 1 Studies., PMID:38822943
Expression of inducible nitric oxide synthase, nitrotyrosine, eosinophilic peroxidase, eotaxin-3, and galectin-3 in patients with gastroesophageal reflux disease, eosinophilic esophagitis, and in healthy controls: a semiquantitative image analysis of 3,3'-diaminobenzidine-stained esophageal biopsies., PMID:38679488
Characterization of the Pro-Inflammatory and Pruritogenic Transcriptome in Skin Lesions of the Experimental Canine Atopic Acute IgE-Mediated Late Phase Reactions Model and Correlation to Acute Skin Lesions of Human Atopic Dermatitis., PMID:38535843
Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia., PMID:38360867
The Role of CCL24 in Primary Sclerosing Cholangitis: Bridging Patient Serum Proteomics to Preclinical Data., PMID:38334601
The Eotaxin-1/CCR3 Axis and Matrix Metalloproteinase-9 Are Critical in Anti-NC16A IgE-Induced Bullous Pemphigoid., PMID:37672029
The Role of CCL24 in Systemic Sclerosis., PMID:37555717
CCL24 regulates biliary inflammation and fibrosis in primary sclerosing cholangitis., PMID:37345655
CD200R signaling contributes to unfavorable tumor microenvironment through regulating production of chemokines by tumor-associated myeloid cells., PMID:37275530
Biomaterials-based immunomodulation enhances survival of murine vascularized composite allografts., PMID:37129566
Eotaxin-2 and eotaxin-3 in malaria exposure and pregnancy., PMID:36380370
CCL24, CXCL9 and CXCL10 are increased in synovial fluid in patients with juvenile idiopathic arthritis requiring advanced treatment., PMID:36342195
Immunomodulatory effects of β-defensin 2 on macrophages induced immuno-upregulation and their antitumor function in breast cancer., PMID:36324077
Cytokines/chemokines and soluble immune checkpoint molecules in anti-GABAB receptor encephalitis., PMID:36270252
CCL24/CCR3 axis plays a central role in angiotensin II-induced heart failure by stimulating M2 macrophage polarization and fibroblast activation., PMID:36131165
Functional IKK/NF-κB signaling in pancreatic stellate cells is essential to prevent autoimmune pancreatitis., PMID:35624133
Study effect of probiotics and prebiotics on treatment of OVA-LPS-induced of allergic asthma inflammation and pneumonia by regulating the TLR4/NF-kB signaling pathway., PMID:35296330
Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves' Disease., PMID:33912135
IL-1α antibody inhibits dose-dependent exacerbation of eosinophilic inflammation by crude house-dust-mite antigen in the conjunctiva of an atopic keratoconjunctivitis mouse model., PMID:33428487
Non-invasive Embryo Assessment: Altered Individual Protein Profile in Spent Culture Media from Embryos Transferred at Day 5., PMID:33151525
Enhanced Type 2 Immune Reactions by Increased IL-22/IL-22Ra1 Signaling in Chronic Rhinosinusitis With Nasal Polyps., PMID:32935490
Increased serum CCL26 level is a potential biomarker for the effectiveness of anti-PD1 antibodies in patients with advanced melanoma., PMID:32658051
Increased CCL24 and CXCL7 levels in the cerebrospinal fluid of patients with neurosyphilis., PMID:32419252
Immune serum-activated human macrophages coordinate with eosinophils to immobilize Ascaris suum larvae., PMID:32394439
Possible Mechanisms of Eosinophil Accumulation in Eosinophilic Pneumonia., PMID:32326200
Biologics or immunotherapeutics for asthma?, PMID:32275962
Differential Gene Expression of Lymphocytes Stimulated with Rhinovirus A and C in Children with Asthma., PMID:32142615
Blocking the autocrine regulatory loop of Gankyrin/STAT3/CCL24/CCR3 impairs the progression and pazopanib resistance of clear cell renal cell carcinoma., PMID:32051393
A blocking monoclonal antibody to CCL24 alleviates liver fibrosis and inflammation in experimental models of liver damage., PMID:32039405
IgG4 Related Autoimmune Pancreatitis: An Overview and the Emerging Role of Serum Eotaxin as a Potential Treatment Target., PMID:31542909
Eosinophil extracellular traps activate type 2 innate lymphoid cells through stimulating airway epithelium in severe asthma., PMID:31330043
Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner., PMID:31285764
Allergic rhinitis is associated with complex alterations in high-density lipoprotein composition and function., PMID:31185305
Blockade of CCL24 with a monoclonal antibody ameliorates experimental dermal and pulmonary fibrosis., PMID:31129606
The Innate Immune Protein S100A9 Protects from T-Helper Cell Type 2-mediated Allergic Airway Inflammation., PMID:30943376
Eosinophils Mediate Basophil-Dependent Allergic Skin Inflammation in Mice., PMID:30910757
A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis., PMID:30252910
Sputum Antineutrophil Cytoplasmic Antibodies in Serum Antineutrophil Cytoplasmic Antibody-Negative Eosinophilic Granulomatosis with Polyangiitis., PMID:30179583
Aggregates of IVIG or Avastin, but not HSA, modify the response to model innate immune response modulating impurities., PMID:30065306
Mesenchymal Stromal Cell (MSC)-Derived Combination of CXCL5 and Anti-CCL24 Is Synergistic and Superior to MSC and Cyclosporine for the Treatment of Graft-versus-Host Disease., PMID:29883796
Extensive serum biomarker analysis in patients with nasopharyngeal carcinoma., PMID:29759660
Novel mediators of statin effects on plaque in HIV: a proteomics approach., PMID:29369166
Interleukin-33 promotes the inflammatory reaction in chronic rhinosinusitis with nasal polyps by NF-κB signaling pathway., PMID:29131267
Commensal microbiota maintains alveolar macrophages with a low level of CCL24 production to generate anti-metastatic tumor activity., PMID:28785009
Human lactoferrin induces asthmatic symptoms in NC/Nga mice., PMID:28774951
Oxidized LDL activated eosinophil polarize macrophage phenotype from M2 to M1 through activation of CD36 scavenger receptor., PMID:28623741
For research use only. Not for human or drug use.
