Anti-Human VEGFB Antibody (SAA0448)

Catalog No.

FHE70310

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

VRF, VEGF-related factor, VEGF-B, Vascular endothelial growth factor B, VEGFB

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P49765

Applications

ELISA, FCM, SPR

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.09% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0448

Advances in Molecular Imaging of VEGFRs: Innovations in Imaging and Therapeutics., PMID:40508182

Transcriptomic and functional characterization of megakaryocytic-derived platelet-like particles: impaired aggregation and prominent anti-tumor effects., PMID:39812346

Vascular endothelial growth factor B-mediated fatty acid flux in the adipose-kidney axis contributes to lipotoxicity in diabetic kidney disease., PMID:39689809

Vascular Endothelial Growth Factor-B Blockade with CSL346 in Diabetic Kidney Disease: A Phase 2A Randomized Controlled Trial., PMID:39150859

Targeting NGF but not VEGFR1 or BDNF signaling reduces endometriosis-associated pain in mice., PMID:39142441

An Anti-VEGF-B Antibody Reduces Abnormal Tumor Vasculature and Enhances the Effects of Chemotherapy., PMID:38791979

Ranibizumab Biosimilars in Treating Retinal Disorders: A Cost-Effective Revolution?, PMID:38347957

Treatment for Gorham-Stout syndrome with a combination of teriparatide and denosumab., PMID:38062162

Vasoregulatory Autoantibodies and Clinical Outcome After Ischemic Stroke-PROSCIS-B., PMID:38014691

Inhibition of VEGF-B signaling prevents non-alcoholic fatty liver disease development by targeting lipolysis in the white adipose tissue., PMID:36717026

Changes in Serum Concentrations of Vascular Endothelial Growth Factors-A and B after Intravitreal Injection of Ranibizumab and Conbercept for Retinopathy of Prematurity., PMID:36709750

Simultaneous blockade of VEGF-B and IL-17A ameliorated diabetic kidney disease by reducing ectopic lipid deposition and alleviating inflammation response., PMID:36646672

Antiangiogenic Molecules Suppressed Meningioma-Induced Neovascularization: A Corneal Angiogenesis Study., PMID:35929040

Combination of sunitinib and 177Lu-labeled antibody cG250 targeted radioimmunotherapy: A promising new therapeutic strategy for patients with advanced renal cell cancer., PMID:35878454

VEGF receptor heterodimers and homodimers are differentially expressed in neuronal and endothelial cell types., PMID:35862373

Salvianolic acid B and ferulic acid synergistically promote angiogenesis in HUVECs and zebrafish via regulating VEGF signaling., PMID:34597652

VEGF-B antibody and interleukin-22 fusion protein ameliorates diabetic nephropathy through inhibiting lipid accumulation and inflammatory responses., PMID:33532185

Intrastromal versus subconjunctival anti-VEGF agents for treatment of corneal neovascularization: a rabbit study., PMID:33469129

Identification of in vitro and in vivo oncolytic effect in colorectal cancer cells by Orf virus strain NA1/11., PMID:33416161

VEGF is an autocrine/paracrine neuroprotective factor for injured retinal ganglion neurons., PMID:32710087

Experimental Models in Neovascular Age Related Macular Degeneration., PMID:32610682

Targeting the vascular endothelial growth factor receptor-1 by the monoclonal antibody D16F7 to increase the activity of immune checkpoint inhibitors against cutaneous melanoma., PMID:32485280

Instability of Non-Standard Microsatellites in Relation to Prognosis in Metastatic Colorectal Cancer Patients., PMID:32429465

Thalidomide suppresses breast cancer tumor growth by inhibiting tumor-associated macrophage accumulation in breast tumor-bearing mice., PMID:32407871

Functional analysis of human fibrocytes derived from monocytes reveals their profibrotic phenotype through paracrine effects., PMID:32378592

Rapid decrease in serum VEGF-A levels may be a worse prognostic biomarker for patients with platinum-resistant recurrent ovarian cancer treated with bevacizumab and gemcitabine., PMID:32279102

Phase I dose-escalation study of the safety, tolerability, and pharmacokinetics of aflibercept in combination with S-1 in Japanese patients with advanced solid malignancies., PMID:31907738

Immune profiling of pre- and post-treatment breast cancer tissues from the SWOG S0800 neoadjuvant trial., PMID:30967156

Increased Expression of Vascular Endothelial Growth Factor-D Following Brain Injury., PMID:30935023

Endothelial Cells Regulate Physiological Cardiomyocyte Growth via VEGFR2-Mediated Paracrine Signaling., PMID:30922063

Vascularization via activation of VEGF-VEGFR signaling is essential for peripheral nerve regeneration., PMID:30531158

Emerging ways to treat breast cancer: will promises be met?, PMID:30259416

VEGF-B is a potent antioxidant., PMID:30249667

Sulodexide inhibits angiogenesis via decreasing Dll4 and Notch1 expression in mouse proepicardial explant cultures., PMID:30246884

Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors., PMID:30170190

VEGF-B electrotransfer mediated gene therapy induces cardiomyogenesis in a rat model of cardiac ischemia., PMID:30015266

Prognostic Value of ACVRL1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study., PMID:29636300

Multiplex quantitative imaging of human myocardial infarction by mass spectrometry-immunohistochemistry., PMID:29556718

Pentoxifylline inhibits angiogenesis via decreasing Dll4 and Notch1 expression in mouse proepicardial explant cultures., PMID:29535000

Colorimetric immunoassays for the screening and specificity evaluation of molecules disturbing VEGFs/VEGFRs interactions., PMID:29284120

Safflower Extract and Aceglutamide Injection Promoting Recovery of Peripheral Innervations via Vascular Endothelial Growth Factor-B Signaling in Diabetic Mice., PMID:29176141

An Anti-VEGF-B Antibody Fragment Induces Regression of Pre-Existing Blood Vessels in the Rat Cornea., PMID:28692735

Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease., PMID:28190774

Hypoxia triggers angiogenesis by increasing expression of LOX genes in 3-D culture of ASCs and ECs., PMID:28189640

Notch Signaling Pathway Regulates Angiogenesis via Endothelial Cell in 3D Co-Culture Model., PMID:27861873

Fusion proteins for treatment of retinal diseases: aflibercept, ziv-aflibercept, and conbercept., PMID:27847621

Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer., PMID:27841282

Expression of Genes Involved in Vascular Morphogenesis and Maturation Predicts Efficacy of Bevacizumab-Based Chemotherapy in Patients Undergoing Liver Resection., PMID:27535973

Response to anti-VEGF-A treatment of retinal pigment epithelial cells in vitro., PMID:27079208

Species Cross-Reactivity of Antibodies Used to Treat Ophthalmic Conditions., PMID:26886891

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