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Anti-Human TGFB3/TGF-beta-3 Antibody (SAA0445)

Catalog #:   FHC81810 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA, FCM
Accession: P10600
Overview

Catalog No.

FHC81810

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

LAP, Transforming growth factor beta-3 proprotein, TGFB3, TGF-beta-3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P10600

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.09% Sodium azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0445

Data Image
References

Silencing TGF-β3 Alleviates Recurrent Spontaneous Abortion Inflammation in Mice: the Importance of Treg/Th17 Cell Balance., PMID:39973551

Allergen-specific B cell responses in oral immunotherapy-induced desensitization, remission, and natural outgrowth in cow's milk allergy., PMID:38989779

Isoform-selective TGF-β3 inhibition for systemic sclerosis., PMID:38272035

GMFB/AKT/TGF-β3 in Müller cells mediated early retinal degeneration in a streptozotocin-induced rat diabetes model., PMID:37904673

First pan-specific vNAR against human TGF-β as a potential therapeutic application: in silico modeling assessment., PMID:36869086

The Development and Characterization of a Highly Sensitive Mature TGFβ3 Assay to Evaluate Anti-TGFβ3 Target Engagement., PMID:36703086

Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-κB and TGF-β2 signaling., PMID:36550569

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice., PMID:36543378

TGF-β3 in differentiation and function of Tph-like cells and its relevance to disease activity in patients with systemic lupus erythematosus., PMID:36370078

Hippo-Yap Signaling Maintains Sinoatrial Node Homeostasis., PMID:36317529

Integrated Analysis of Cytokine Profiles in Malaria Patients Discloses Selective Upregulation of TGF-β1, β3, and IL-9 in Mild Clinical Presentation., PMID:36293524

Immune landscape of distinct subtypes in urothelial carcinoma based on immune gene profile., PMID:36003383

Latent transforming growth factor β binding protein 3 controls adipogenesis., PMID:35933071

Metabolic regulation of intrasynovial flexor tendon repair: The effects of dichloroacetate administration on early tendon healing in a canine model., PMID:35488732

Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338

Generation of endoplasmic reticulum stress-dependent reactive oxygen species mediates TGF-β1-induced podocyte migration., PMID:34993544

Dramatic activation of an antibody by a single amino acid change in framework., PMID:34785671

TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer., PMID:34561272

TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis., PMID:34349032

Progression of melanoma is suppressed by targeting all transforming growth factor‑β isoforms with an Fc chimeric receptor., PMID:34296292

COL11A1 activates cancer-associated fibroblasts by modulating TGF-β3 through the NF-κB/IGFBP2 axis in ovarian cancer cells., PMID:34117361

Fibroinflammatory Signatures Increase with Age in the Human Ovary and Follicular Fluid., PMID:34063149

Rat Milk and Plasma Immunological Profile throughout Lactation., PMID:33920419

Cyclophosphamide suppresses spermatogenesis in the testis of mice through downregulation of miR-34b and miR-34c., PMID:33900636

TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism., PMID:33637600

Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes., PMID:33529332

Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders., PMID:33384688

Increased Stromal Infiltrating Lymphocytes Are Associated with the Risk of Disease Progression in Mesenchymal Circulating Tumor Cell-Positive Primary Breast Cancer Patients., PMID:33322711

Deficiency in the frequency and function of Tr1 cells in IgAV and the possible role of IL-27., PMID:33280050

Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer., PMID:32917858

TGF-β3 Induces Autophagic Activity by Increasing ROS Generation in a NOX4-Dependent Pathway., PMID:32082074

Increased Cell Detachment Ratio of Mesenchymal-Type Lung Cancer Cells on pH-Responsive Chitosan through the β3 Integrin., PMID:31771240

Arginine accelerates intestinal health through cytokines and intestinal microbiota., PMID:31757675

Combination therapy in the Col1a2G610C mouse model of Osteogenesis Imperfecta reveals an additive effect of enhancing LRP5 signaling and inhibiting TGFβ signaling on trabecular bone but not on cortical bone., PMID:31648079

Intermittent compressive force promotes osteogenic differentiation in human periodontal ligament cells by regulating the transforming growth factor-β pathway., PMID:31591384

Inhibition of the Progression of Skin Inflammation, Fibrosis, and Vascular Injury by Blockade of the CX3 CL1/CX3 CR1 Pathway in Experimental Mouse Models of Systemic Sclerosis., PMID:31173491

Effects of host fatty acid-binding protein 4 on Eimeria tenella sporozoites invasion of cells., PMID:31069534

Immune profiling of pre- and post-treatment breast cancer tissues from the SWOG S0800 neoadjuvant trial., PMID:30967156

Potential function of TGF-β isoforms in maturation-stage ameloblasts., PMID:30929801

Chondrogenesis-inductive nanofibrous substrate using both biological fluids and mesenchymal stem cells from an autologous source., PMID:30813000

Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells., PMID:30642980

Radio resistance in breast cancer cells is mediated through TGF-β signalling, hybrid epithelial-mesenchymal phenotype and cancer stem cells., PMID:30579251

P311 Promotes Lung Fibrosis via Stimulation of Transforming Growth Factor-β1, -β2, and -β3 Translation., PMID:30230348

MFG-E8/integrin β3 signaling contributes to airway inflammation response and airway remodeling in an ovalbumin-induced murine model of asthma., PMID:30076648

TGF-β1 modulates podocyte migration by regulating the expression of integrin-β1 and -β3 through different signaling pathways., PMID:30021392

Inhibition of integrin αVβ6 changes fibril thickness of stromal collagen in experimental carcinomas., PMID:29966518

TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration., PMID:29795291

Phase I Trial of M7824 (MSB0011359C), a Bifunctional Fusion Protein Targeting PD-L1 and TGFβ, in Advanced Solid Tumors., PMID:29298798

Immunohistochemical Analysis on Cortex-to-Cortex Healing After Mandibular Vertical Ramus Osteotomy: A Preliminary Study., PMID:29112826

TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms., PMID:28729364

Datasheet
$ 198
Product specifications
50 μg 198 100 μg 328

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For research use only. Not for human or drug use.

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Anti-Human TGFB3/TGF-beta-3 Antibody (SAA0445) [FHC81810]
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