Catalog No.
FHC15710
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
Endothelial cell growth factor, HBGF-1, Fibroblast growth factor 1, FGF1, ECGF, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, FGF-1, FGFA
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P05230
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0436
PRELP inhibits colorectal cancer progression by suppressing epithelial-mesenchymal transition and angiogenesis via the inactivation of the FGF1/PI3K/AKT pathway., PMID:39242474
Fibroblast Growth Factor Receptors and Ligands in Context of Bevacizumab Response in Ovarian Carcinoma: An Exploratory Analysis of AGO-OVAR11/ICON-7., PMID:38154497
ERK1/2-dependent activity of SOX9 is required for sublytic C5b-9-induced expression of FGF1, PDGFα, and TGF-β1 in rat Thy-1 nephritis., PMID:38118314
Analysis of proteins released from osteoarthritic cartilage by compressive loading., PMID:37880329
Virtual Screening of Protein Data Bank via Docking Simulation Identified the Role of Integrins in Growth Factor Signaling, the Allosteric Activation of Integrins, and P-Selectin as a New Integrin Ligand., PMID:37759488
Discovery of novel thymidylate synthase (TS) inhibitors that influence cancer angiogenesis and metabolic reprogramming in NSCLC cells., PMID:37437348
Application of an antibody microarray for serum protein profiling of coronary artery stenosis., PMID:36166954
Fibroblast Growth Factor-Based Pharmacotherapies for the Treatment of Obesity-Related Metabolic Complications., PMID:36100222
Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer., PMID:35624341
Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients., PMID:35488348
FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2-/- Mouse Model of Primary Sclerosing Cholangitis., PMID:35271760
Phage-Displayed Mimotopes of SARS-CoV-2 Spike Protein Targeted to Authentic and Alternative Cellular Receptors., PMID:35215976
The potential value of amlexanox in the treatment of cancer: Molecular targets and therapeutic perspectives., PMID:34968491
Regulation of Transplanted Cell Homing by FGF1 and PDGFB after Doxorubicin Myocardial Injury., PMID:34831221
FGF1 Fusions with the Fc Fragment of IgG1 for the Assembly of GFPpolygons-Mediated Multivalent Complexes Recognizing FGFRs., PMID:34439755
Sublytic C5b-9 triggers glomerular mesangial cell proliferation via enhancing FGF1 and PDGFα gene transcription mediated by GCN5-dependent SOX9 acetylation in rat Thy-1 nephritis., PMID:34156114
Expression and localization of FGFR1, FGFR2 and CTGF during normal human lung development., PMID:33962151
Overexpression of GDNF and FGF-1 in Canine Benign Prostatic Hyperplasia: Evidence for a Pathogenetic Role of Neural Growth Factor., PMID:33494907
Transcriptomics Study to Determine the Molecular Mechanism by which sIL-13Rα2-Fc Inhibits Caudal Intervertebral Disc Degeneration in Rats., PMID:32855969
Levels of plasma glycan-binding auto-IgG biomarkers improve the accuracy of prostate cancer diagnosis., PMID:32816187
Fibroblast Growth Factor (FGF) Signaling Protects Against Acute Pancreatitis-Induced Damage by Modulating Inflammatory Responses., PMID:32283546
High levels of Notch intracellular cleaved domain are associated with stemness and reduced bevacizumab efficacy in patients with advanced colon cancer., PMID:31578584
Fibroblast growth factor-1 as a mediator of paracrine effects of canine adipose tissue-derived mesenchymal stem cells on in vitro-induced insulin resistance models., PMID:30445954
An Engineered Human Fibroblast Growth Factor-1 Derivative, TTHX1114, Ameliorates Short-term Corneal Nitrogen Mustard Injury in Rabbit Organ Cultures., PMID:30267094
Specific Antibody Fragment Ligand Traps Blocking FGF1 Activity., PMID:30134556
Humanization of fibroblast growth factor 1 single-chain antibody and validation for its antitumorigenic efficacy in breast cancer and glioma cells., PMID:29575613
Assessment of FGFR1 Over-Expression and Over-Activity in Lung Cancer Cells: A Toolkit for Anti-FGFR1 Drug Screening., PMID:29281903
Simple and Efficient Purification of Recombinant Proteins Using the Heparin-Binding Affinity Tag., PMID:29091276
Tumor-induced osteomalacia., PMID:29021995
SHuffle™ T7 strain is capable of producing high amount of recombinant human fibroblast growth factor-1 (rhFGF-1) with proper physicochemical and biological properties., PMID:28827102
High-Yield Site-Specific Conjugation of Fibroblast Growth Factor 1 with Monomethylauristatin E via Cysteine Flanked by Basic Residues., PMID:28598150
Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells., PMID:28510269
The primary growth of laryngeal squamous cell carcinoma cells in vitro is effectively supported by paired cancer-associated fibroblasts alone., PMID:28475003
Quantification of a Non-conventional Protein Secretion: The Low-Molecular-Weight FGF-2 Example., PMID:27665555
Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy., PMID:27563235
Assessment of Plasma Cytokine Profile Changes in Bevacizumab-Treated Retinopathy of Prematurity Infants., PMID:27054517
Cell surface localization of importin α1/KPNA2 affects cancer cell proliferation by regulating FGF1 signalling., PMID:26887791
Formation of vascular network structures within cardiac cell sheets from mouse embryonic stem cells., PMID:31245454
Sustained Inhibition of Proliferative Response After Transient FGF Stimulation Is Mediated by Interleukin 1 Signaling., PMID:26218437
FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7., PMID:26183471
Cell Injury-Induced Release of Fibroblast Growth Factor 2: Relevance to Intracerebral Mesenchymal Stromal Cell Transplantations., PMID:25873141
Beneficial effects of coculturing synovial derived mesenchymal stem cells with meniscus fibrochondrocytes are mediated by fibroblast growth factor 1: increased proliferation and collagen synthesis., PMID:25852755
Inhibition of transforming growth factor β (TGF-β) signaling can substitute for Oct4 protein in reprogramming and maintain pluripotency., PMID:25548277
Angiostatic, tumor inflammatory and anti-tumor effects of CXCL4(47-70) and CXCL4L1(47-70) in an EGF-dependent breast cancer model., PMID:25373734
Quantification of the effects of mutations on receptor tyrosine kinase (RTK) activation in mammalian cells., PMID:25319891
The FGF-1-specific single-chain antibody scFv1C9 effectively inhibits breast cancer tumour growth and metastasis., PMID:25124967
Probing structurally altered and aggregated states of therapeutically relevant proteins using GroEL coupled to bio-layer interferometry., PMID:25043635
Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications., PMID:24668773
Protein comparability assessments and potential applicability of high throughput biophysical methods and data visualization tools to compare physical stability profiles., PMID:24659968
Comparison of the neuropoietic activity of gene-modified versus parental mesenchymal stromal cells and the identification of soluble and extracellular matrix-related neuropoietic mediators., PMID:24572070
For research use only. Not for human or drug use.
