The role of IGF-2 and its variants in enhancing endothelial migration and angiogenesis., PMID:40454313
Antibody reactivity in cerebrospinal fluid and serum against the insulin-insulin-like growth factor 2 (INS-IGF2) protein is associated with psychotic symptomatology in patients with schizophrenia or related psychosis., PMID:40319454
A validated liquid chromatography-tandem mass spectrometry assay for simultaneous quantitation of intact IGF-1 and IGF-2 in human serum., PMID:40158466
Refractory Hypoglycemia Secondary to the Warburg Effect in Diffuse Large B-Cell Lymphoma., PMID:40103858
Engineering IGF2 for Lysosome-targeting chimeras development to target drug-resistant membrane proteins in tumor therapy., PMID:39969096
Proteomic evaluation of borosilicate hybrid sol-gel coatings with osteogenic, immunomodulatory and antibacterial properties., PMID:39956001
Serological markers of exocrine pancreatic function are differentially informative for distinguishing individuals progressing to type 1 diabetes., PMID:39755561
Paraneoplastic hypoglycemia: An overview for optimal clinical guidance., PMID:39185033
Autocrine insulin-like growth factor 2 signaling as a potential target in the associated development of pulmonary emphysema and cancer in smokers., PMID:38902841
Diagnostic and prognostic assessments of adrenocortical carcinomas by pathological features, immunohistochemical markers and reticular histochemistry staining., PMID:38802933
Beckwith-Wiedemann syndrome with juvenile fibrous nodules and lobular breast tumors: a case report and review of the literature., PMID:38514513
IGF-2-mediated hypoglycemia: a case series and review of the medical therapies for refractory hypoglycemia., PMID:38432069
Combination of Atractylenolide I, Atractylenolide III, and Paeoniflorin promotes angiogenesis and improves neurological recovery in a mouse model of ischemic Stroke., PMID:38178130
IGF2 Peptide-Based LYTACs for Targeted Degradation of Extracellular and Transmembrane Proteins., PMID:38005242
Insulin-like Growth Factor 2 (IGF2)-Fused Lysosomal Targeting Chimeras for Degradation of Extracellular and Membrane Proteins., PMID:37899626
XENERA-1: a randomised double-blind Phase II trial of xentuzumab in combination with everolimus and exemestane versus everolimus and exemestane in patients with hormone receptor-positive/HER2-negative metastatic breast cancer and non-visceral disease., PMID:37308971
Extensive cytokine biomarker analysis in serum of Guillain-Barré syndrome patients., PMID:37221406
Case report: Severe, refractory hypoglycemia in a 9-year-old Brittany Spaniel with renal nephroblastoma., PMID:37143502
Safety, pharmacokinetics and CNS distribution of tralesinidase alfa administered via intracerebroventricular infusion to juvenile cynomolgus monkeys., PMID:36923444
Inhibition of the epigenetically activated miR-483-5p/IGF-2 pathway results in rapid loss of meningioma tumor cell viability., PMID:36809604
Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma., PMID:36780225
Disturbance of suprachiasmatic nucleus function improves cardiac repair after myocardial infarction by IGF2-mediated macrophage transition., PMID:36747104
Results of TRIO-15, a multicenter, open-label, phase II study of the efficacy and safety of ganitumab in patients with recurrent platinum-sensitive ovarian cancer., PMID:36709663
IL-1β promotes osteoclastogenesis by increasing the expression of IGF2 and chemokines in non-osteoclastic cells., PMID:36522118
miR-375 upregulates lipid metabolism and inhibits cell proliferation involved in chicken fatty liver formation and inheritance via targeting recombination signal binding protein for immunoglobulin kappa J region (RBPJ)., PMID:36410068
IGF-2 mediated hypoglycemia and the paradox of an apparently benign lesion: a case report & review of the literature., PMID:36303203
Insulin-like growth factor 2 promotes osteoclastogenesis increasing inflammatory cytokine levels under hypoxia., PMID:35641033
[Dihydromyricetin reverses Herceptin resistance by up-regulating miR-98-5p and inhibiting IGF1R/HER2 dimer formation in SKBR3 cells]., PMID:35365444
A phase 1 trial of xentuzumab, an IGF-neutralizing antibody, in Japanese patients with advanced solid tumors., PMID:34870878
MiR-98-5p/IGF2 Axis Influence Herceptin Sensitivity through IGF1R/HER2 Heterodimer Formation and AKT/mTOR Signal Pathway in HER2 Positive Breast Cancer., PMID:34837929
Two Distinct Lysosomal Targeting Strategies Afford Trojan Horse Antibodies With Pan-Filovirus Activity., PMID:34721393
INSULIN-LIKE GROWTH FACTORS IN THE SERUM OF PATIENTS WITH PAPILLARY THYROID CANCER., PMID:34537745
M2‑like tumour‑associated macrophage‑secreted IGF promotes thyroid cancer stemness and metastasis by activating the PI3K/AKT/mTOR pathway., PMID:34184083
Phaeochromocytomas overexpress insulin transcript and produce insulin., PMID:34170845
Disruption of FOXO3a-miRNA feedback inhibition of IGF2/IGF-1R/IRS1 signaling confers Herceptin resistance in HER2-positive breast cancer., PMID:33976188
Insulin-like growth factor-2 regulates basal retinal insulin receptor activity., PMID:33915127
An antibody-free LC-MS/MS method for the quantification of intact insulin-like growth factors 1 and 2 in human plasma., PMID:33569646
Cell sheet technology: Influence of culture conditions on in vitro-cultivated corneal stromal tissue for regenerative therapies of the ocular surface., PMID:33538123
Inceptor counteracts insulin signalling in β-cells to control glycaemia., PMID:33505018
Biomolecular assembly on interdigitated electrode nanosensor for selective detection of insulin-like growth factor-1., PMID:33467925
A phase Ib/II study of xentuzumab, an IGF-neutralising antibody, combined with exemestane and everolimus in hormone receptor-positive, HER2-negative locally advanced/metastatic breast cancer., PMID:33451345
Salinity, Temperature and Ammonia Acute Stress Response in Seabream (Sparus aurata) Juveniles: A Multidisciplinary Study., PMID:33419050
Age, Diet and Epidermal Signaling Modulate Dermal Fibroblasts' Adipogenic Potential., PMID:33255750
Influence of Lacto-Immuno-Vital on growth performance and gene expression of IgA, MUC-2, and growth factor IGF-2 in the jejunum of broiler chickens., PMID:33248572
A radioligand binding assay for the insulin-like growth factor 2 receptor., PMID:32877466
Rare causes of hypoglycemia in adults., PMID:32409005
Custom DNA Microarrays Reveal Diverse Binding Preferences of Proteins and Small Molecules to Thousands of G-Quadruplexes., PMID:32216326
Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumours., PMID:32161368
Multiple Growth Factor Targeting by Engineered Insulin-like Growth Factor Binding Protein-3 Augments EGF Receptor Tyrosine Kinase Inhibitor Efficacy., PMID:32066763
High-performance detection of an abdominal aortic aneurysm biomarker by immunosensing., PMID:31876964
For research use only. Not for human or drug use.
