Catalog No.
VHF68001
Species reactivity
Human
Host species
Human
Isotype
IgG2, kappa
Clonality
Monoclonal
Target
Small-inducible cytokine D1, Fractalkine, Neurotactin, C-X3-C motif chemokine 1, NTT, CX3CL1, SCYD1, FKN, CX3C membrane-anchored chemokine
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P78423
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0091
Polyphyllin VII promotes hepatic stellate cell ferroptosis via the HIC1/CX3CL1/GPX4 axis., PMID:40496063
Overexpression of CX3CL1-CX3CR1 Signaling in the Stria Vascularis rather than the Basilar Membrane May Be the Trigger for Inflammaging in the Cochlea., PMID:40058359
LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress., PMID:39900910
Conversion of placental hemogenic endothelial cells to hematopoietic stem and progenitor cells., PMID:39875377
Resveratrol ameliorates postoperative cognitive dysfunction in aged mice by regulating microglial polarization through CX3CL1/CX3CR1 signaling axis., PMID:39716583
The hypervirulent Group B Streptococcus HvgA adhesin promotes central nervous system invasion through transcellular crossing of the choroid plexus., PMID:39152442
Dysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology., PMID:38956605
Double-faced CX3CL1 enhances lymphangiogenesis-dependent metastasis in an aggressive subclone of oral squamous cell carcinoma., PMID:38775151
Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines., PMID:38630384
VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis., PMID:38618956
CX3CL1 and its receptor CX3CR1 interact with RhoA signaling to induce paclitaxel resistance in gastric cancer., PMID:38601629
Metadherin promotes stem cell phenotypes and correlated with immune infiltration in hepatocellular carcinoma., PMID:38516242
Lactate/GPR81 recruits regulatory T cells by modulating CX3CL1 to promote immune resistance in a highly glycolytic gastric cancer., PMID:38419759
PVT1 promotes proliferation and macrophage immunosuppressive polarization through STAT1 and CX3CL1 regulation in glioblastoma multiforme., PMID:38287522
Direct interaction of platelet with tumor cell aggravates hepatocellular carcinoma metastasis by activating TLR4/ADAM10/CX3CL1 axis., PMID:38280480
CB2 agonist mitigates cocaine-induced reinstatement of place preference and modulates the inflammatory response in mice., PMID:38085651
Sex- and age-related differences in the inflammatory properties of cardiac fibroblasts: impact on the cardiosplenic axis and cardiac fibrosis., PMID:38054090
Blockage of CacyBP inhibits macrophage recruitment and improves anti-PD-1 therapy in hepatocellular carcinoma., PMID:37968706
Biomarkers of ocular allergy and dry eye disease., PMID:37876509
Targeted inhibition of CX3CL1 limits podocytes ferroptosis to ameliorate cisplatin-induced acute kidney injury., PMID:37875838
The cellular microenvironment regulates CX3CR1 expression on CD8+ T cells and the maintenance of CX3CR1+ CD8+ T cells., PMID:37816219
Soluble CX3CL1-expressing retinal pigment epithelium cells protect rod photoreceptors in a mouse model of retinitis pigmentosa., PMID:37605279
Chemokine/ITGA4 Interaction Directs iPSC-Derived Myogenic Progenitor Migration to Injury Sites in Aging Muscle for Regeneration., PMID:37508502
Therapeutic role of mesenchymal stem cell-derived extracellular vesicles in neuroinflammation and cognitive dysfunctions induced by binge-like ethanol treatment in adolescent mice., PMID:37381698
Plasma fractalkine contributes to systemic myeloid diversity and PD-L1/PD-1 blockade in lung cancer., PMID:37366231
CX3CR1 deficiency-induced TIL tumor restriction as a novel addition for CAR-T design in solid malignancies., PMID:37070068
"Find-eat" strategy targeting endothelial cells via receptor functionalized apoptotic body nanovesicle., PMID:36973107
Microglia sustain anterior cingulate cortex neuronal hyperactivity in nicotine-induced pain., PMID:36944965
Potential role of the hydroxyl carboxylic acid receptor type 2 (HCAR2) in microglia pathophysiology: A possible cross-talk with C-X-C chemokine receptor 1 (CXCR1)., PMID:36796675
Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids., PMID:36793710
Fractalkine enhances oligodendrocyte regeneration and remyelination in a demyelination mouse model., PMID:36608690
CX3CL1 promotes cell sensitivity to ferroptosis and is associated with the tumor microenvironment in clear cell renal cell carcinoma., PMID:36397015
Vascular Protective Effects of Malus toringoides (Rehd.) Hughes Extracts and their Mechanism in Diabetic Rats and HUVECs., PMID:36310615
Postoperative Plasmacytoid Dendritic Cells Secrete IFNα to Promote Recruitment of Myeloid-Derived Suppressor Cells and Drive Hepatocellular Carcinoma Recurrence., PMID:36112065
Concentration and proteolysis of CX3CL1 may regulate the microglial response to CX3CL1., PMID:36106533
CX3CL1/CX3CR1 interaction protects against lipotoxicity-induced nonalcoholic steatohepatitis by regulating macrophage migration and M1/M2 status., PMID:35914622
CX3CL1 Action on Microglia Protects from Diet-Induced Obesity by Restoring POMC Neuronal Excitability and Melanocortin System Activity Impaired by High-Fat Diet Feeding., PMID:35742824
Laminar shear stress alleviates monocyte adhesion and atherosclerosis development via miR-29b-3p/CX3CL1 axis regulation., PMID:35735031
Astragaloside IV Alleviates Renal Tubular Epithelial-Mesenchymal Transition via CX3CL1-RAF/MEK/ERK Signaling Pathway in Diabetic Kidney Disease., PMID:35669284
Asperosaponin VI ameliorates the CMS-induced depressive-like behaviors by inducing a neuroprotective microglial phenotype in hippocampus via PPAR-γ pathway., PMID:35610721
Suppression of CX3CL1 by miR-497-5p inhibits cell growth and invasion through inactivating the ERK/AKT pathway in NSCLC cells., PMID:35485293
CX3CL1 inhibits NLRP3 inflammasome-induced microglial pyroptosis and improves neuronal function in mice with experimentally-induced ischemic stroke., PMID:35461837
Neuron derived fractalkine promotes microglia to absorb hematoma via CD163/HO-1 after intracerebral hemorrhage., PMID:35389112
Blockage of CX3CL1 Attenuates Platelet and Leukocyte Recruitment in Murine Hepatic I/R., PMID:35279656
An overlooked subset of Cx3cr1wt/wt microglia in the Cx3cr1CreER-Eyfp/wt mouse has a repopulation advantage over Cx3cr1CreER-Eyfp/wt microglia following microglial depletion., PMID:35062962
ApoA-I mimetics reduce systemic and gut inflammation in chronic treated HIV., PMID:34995311
Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players., PMID:34864314
The Clinical Implications and Molecular Mechanism of CX3CL1 Expression in Urothelial Bladder Cancer., PMID:34671562
Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure., PMID:34504250
RNA editing enzyme adenosine deaminases acting on RNA 1 deficiency increases the sensitivity of non-small cell lung cancer cells to anlotinib by regulating CX3CR1-fractalkine expression., PMID:34319598
For research use only. Not for human or drug use.
