Catalog No.
VHE55401
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Applications
ELISA, Neutralization
Target
Intercrine reduced in hepatomas, hSDF-1, Stromal cell-derived factor 1, SDF-1, Pre-B cell growth-stimulating factor, SDF1, SDF1A, C-X-C motif chemokine 12, SDF1B, CXCL12, IRH, PBSF, hIRH
Concentration
2.07 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P48061
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0090
Note
For research use only. Not suitable for clinical or therapeutic use.
Pulse Activation of Retinoic Acid Receptor Enhances Hematopoietic Stem Cell Homing by Controlling CXCR4 Membrane Presentation., PMID:39480614
CXCL12/CXCR4 pathway as a novel therapeutic target for RNF213-associated pulmonary arterial hypertension., PMID:39496725
Bone marrow mesenchymal stem cells overexpressing stromal cell- derived factor 1 aid in bone formation in osteoporotic mice., PMID:39497150
Combination CXCR4 and PD-1 Blockade Enhances Intratumoral Dendritic Cell Activation and Immune Responses Against Hepatocellular Carcinoma., PMID:39514263
Reparative homing of bone mesenchymal stem cells induced by iMSCs via the SDF-1/CXCR4 axis for articular cartilage defect restoration., PMID:39536539
Erratum: CXCL12 chemokine expression suppresses human breast cancer growth and metastasis in vitro and in vivo., PMID:39544711
Bioactive Porous Composite Implant Guides Mesenchymal Stem Cell Differentiation and Migration to Accelerate Bone Reconstruction., PMID:39583325
PDGFRα-positive cell-derived TIMP-1 modulates adaptive immune responses to influenza A viral infection., PMID:39585242
Modeling Lymphoma Angiogenesis, Lymphangiogenesis, and Vessel Co-Option, and the Effects of Inhibition of Lymphoma-Vessel Interactions with an αCD20-EndoP125A Antibody Fusion Protein., PMID:39594584
Isoferulic acid regulates CXCL12/CXCR4-mediated apoptosis and autophagy in podocyte and mice with STZ-induced diabetic nephropathy., PMID:39616856
Natural lung-tropic TH9 cells: a sharp weapon for established lung metastases., PMID:39631847
Piperine attenuates cancer-associated pain induced by microglial activation via increasing miR-150-50p., PMID:39641645
Regulation of the chemokine receptors CXCR4 and ACKR3 by receptor activity-modifying proteins., PMID:39662834
The nuclear condensates of ESE3/EHF induce cellular senescence without the associated inflammatory secretory phenotype in pancreatic ductal adenocarcinoma., PMID:39710057
Locked Dimerized CXCL12 Exerts Radiosensitizing Effects in Head and Neck Cancer., PMID:39722591
A1, an innovative fluorinated CXCR4 inhibitor, redefines the therapeutic landscape in colorectal cancer., PMID:39757159
Disturbed shear stress promotes atherosclerosis through TRIM21-regulated MAPK6 degradation and consequent endothelial inflammation., PMID:39763069
A Bait-and-Hook Hydrogel for Net Tumor Cells to Enhance Chemotherapy and Mitigate Metastatic Dissemination., PMID:39771496
Inhibition of Abdominal Aortic Aneurysm Progression Through the CXCL12/CXCR4 Axis via MiR206-3p Sponge., PMID:39779470
Inhibition of Mitochondrial Succinate Dehydrogenase with Dimethyl Malonate Promotes M2 Macrophage Polarization by Enhancing STAT6 Activation., PMID:39806091
Evaluating the transcriptional regulators of arterial gene expression via a catalogue of characterized arterial enhancers., PMID:39819837
ERG mediates the differentiation of hepatic progenitor cells towards immunosuppressive PDGFRα+ cancer-associated fibroblasts during hepatocarcinogenesis., PMID:39827226
Sexual dimorphism in the mouse bone marrow niche regulates hematopoietic engraftment via sex-specific Kdm5c/Cxcl12 signaling., PMID:39836478
Rap1 Guanosine Triphosphate Hydrolase (GTPase) Regulates Shear Stress-Mediated Adhesion of Mesenchymal Stromal Cells., PMID:39857326
Bisphenol A-induced cancer-associated adipocytes promotes breast carcinogenesis via CXCL12/AKT signaling., PMID:39863150
Signal peptide-independent secretion of keratin-19 by pancreatic cancer cells., PMID:39896665
Injectable myocardium-derived hydrogels with SDF-1α releasing for cardiac repair., PMID:39908684
Modulation of biomaterial-induced foreign body response by regulating the differentiation and migration of Treg cells through the CXCL12-CXCR4/7 axis., PMID:39932368
Effects of FAP+ fibroblasts on cell proliferation migration and immunoregulation of esophageal squamous carcinoma cells through the CXCL12/CXCR4 axis., PMID:39934460
Counteracting immunodepression by extracellular matrix hydrogel to promote brain tissue remodeling and neurological function recovery after traumatic brain injury., PMID:39970603
The lncRNA MIR181A1HG in extracellular vesicles derived from highly metastatic colorectal cancer cells promotes liver metastasis by remodeling the extracellular matrix and recruiting myeloid-derived suppressor cells., PMID:39972363
Notch1 siRNA and AMD3100 Ameliorate Metabolic Dysfunction-Associated Steatotic Liver Disease., PMID:40002899
Generation of Orthogonal Gradients of the Matrix Stiffness and Chemotactic Cues in a Suspended Array of Hydrogel to Study hMSCs Migration., PMID:40021359
Diphlorethohydroxycarmalol inhibits Müller cell gliosis by disrupting CXCR4/CXCL12 interaction in violet-blue light-induced retinal phototoxicity., PMID:40034286
SDF-1 alleviates osteoarthritis by resolving mitochondrial dysfunction through the activation of the Sirt3/PGC-1α signalling pathway., PMID:40055825
Unraveling the crucial role of SDF-1 in osteoarthritis progression: IL6/HIF-1α positive feedback and chondrocyte ferroptosis., PMID:40058106
Chemokine induces phase transition from non-directional to directional migration during angiogenesis., PMID:40074350
IL6-Dependent PIEZO1 Activation Promotes M1-Mediated Orthodontic Root Resorption via CXCL12/CXCR4., PMID:40077814
In Vitro Bioactivity Evaluation of IL-4 and SDF-1 Mimicking Peptides Engineered to Enhance Skeletal Muscle Reconstruction., PMID:40087853
CXCL12/CXCR4 axis mediates CD8 + T cell overactivation in the progression of viral myocarditis., PMID:40186195
CXCL12 alone is enough to Reprogram Normal Fibroblasts into Cancer-Associated Fibroblasts., PMID:40199862
SDF-1α mRNA therapy in peripheral artery disease., PMID:40314870
Single-cell RNA sequencing reveals a fibroblast gene signature that promotes T-cell infiltration in muscle-invasive bladder cancer., PMID:40319103
Beneficial but diverse influence of custom-designed hydrogels modified with IL-4 and SDF-1 peptides on selected populations of cells essential for skeletal muscle regeneration., PMID:40381767
Highly Specific Cytokine Receptor-Targeting Chimeras for Targeted Membrane Protein Degradation and Sensitization of Osimertinib in EGFR-Mutated Non-Small-Cell Lung Cancer., PMID:40401615
Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury., PMID:40401637
GliaTrap is a biodegradable, non-swelling and non-inflammatory hydrogel with tuned release of CXCL12 to attract migrating glioblastoma cells., PMID:40404745
Spatial multiomics decipher fibroblast-macrophage dynamics in systemic sclerosis., PMID:40410053
Exosomal CMTM4 Induces Immunosuppressive Macrophages to Promote Ovarian Cancer Progression and Attenuate Anti-PD-1 Immunotherapy., PMID:40433989
Unraveling anti-atherosclerosis mechanism of anthocyanins from Xinjiang wild cherry plum (Prunus divaricata Ledeb) via network pharmacology and molecular docking., PMID:40478326
For research use only. Not for human or drug use.
