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InVivoMAb Anti-Human CXCL11/I-TAC (Iv0089)

Catalog #:   VHA24601 Specific References (50) DATASHEET
Host species: Human
Isotype: VHH-hFc
Applications: ELISA, Neutralization
Accession: O14625
Overview

Catalog No.

VHA24601

Species reactivity

Human

Host species

Human

Isotype

VHH-hFc

Clonality

Monoclonal

Target

IP-9, I-TAC, C-X-C motif chemokine 11, ITAC, Small-inducible cytokine B11, SCYB11, Beta-R1, Interferon gamma-inducible protein 9, H174, SCYB9B, CXCL11, Interferon-inducible T-cell alpha chemoattractant

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O14625

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Iv0089

Data Image
References

Gene signature-guided isolation identifies cucurbitacins as STAT3 inhibitors from Picria fel-terrae Lour., PMID:40505486

The metastatic role of the CXCL10-CXCR3 axis and its therapeutic potential in osteosarcoma., PMID:40502679

Chemokine (C-X-C motif) ligand 11 is a crucial antiviral modulator that affects viral replication, the IFN-γ response, and T-cell functions during respiratory syncytial virus infection., PMID:40447278

Inhibition of MBTPS1 enhances antitumor immunity and potentiates anti-PD-1 immunotherapy., PMID:40307212

Circ_0098181 binds PKM2 to attenuate liver fibrosis., PMID:40248098

Altered cytokine release of airway epithelial cells in vitro by combinations of respiratory syncytial virus, Streptococcus pneumoniae, Printex 90 and diesel exhaust particles., PMID:40118319

ITGAX promotes Th17-cell differentiation and drives pathogenesis in pediatric ulcerative colitis., PMID:40099533

IKZF1 and Ikaros Overexpression Results in Alopecia Areata-Like Phenotype in Mice., PMID:40066904

Plac1+ Tumor Cell-Treg Interplay Supports Tumorigenesis and Progression of Head and Neck Cancer., PMID:40056047

Fc-competent TIGITx4-1BB bispecific antibody exerts potent long-lasting antitumor activity by potentiating CD8+ T cell activity and Fcγ receptor-mediated modulation of the tumor microenvironment., PMID:40010766

Nanostructured lipid carriers based mRNA vaccine leads to a T cell-inflamed tumour microenvironment favourable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumour model., PMID:39793480

CXCL11 reprograms M2-biased macrophage polarization to alleviate pulmonary fibrosis in mice., PMID:39548525

PD-1 and CTLA-4 serve as major gatekeepers for effector and cytotoxic T-cell potentiation by limiting a CXCL9/10-CXCR3-IFNγ positive feedback loop., PMID:39474427

Lambda carrageenan displays antiviral activity against the infectious pancreatic necrosis virus (IPNV) by inhibiting viral replication and enhancing innate immunity in salmonid cells., PMID:39454921

Excessive Erythrophagocytosis Accounts for Systemic Inflammation in Chronic Kidney Disease., PMID:39398228

Systemic delivery of tannic acid-ferric-masked oncolytic adenovirus reprograms tumor microenvironment for improved therapeutic efficacy in glioblastoma., PMID:39385009

CXCR3-CXCL11 Signaling Restricts Angiogenesis and Promotes Pericyte Recruitment., PMID:39360413

Rap1A Modulates Store-Operated Calcium Entry in the Lung Endothelium: A Novel Mechanism Controlling NFAT-Mediated Vascular Inflammation and Permeability., PMID:39324266

EGR2 is an epigenomic regulator of phagocytosis and antifungal immunity in alveolar macrophages., PMID:39042472

Psoralen attenuates cigarette smoke extract-induced inflammation by modulating CD8+ T lymphocyte recruitment and chemokines via the JAK2/STAT1 signaling pathway., PMID:38988534

Harnessing lipid metabolism modulation for improved immunotherapy outcomes in lung adenocarcinoma., PMID:38977328

S100A8-Mediated Inflammatory Signaling Drives Colorectal Cancer Progression via the CXCL5/CXCR2 Axis., PMID:38817853

Differential gene expression and immune cell infiltration in maedi-visna virus-infected lung tissues., PMID:38816794

Alpha 7 Nicotinic Acetylcholine Receptor Agonist PHA 568487 Reduces Acute Inflammation but Does Not Affect Cardiac Function or Myocardial Infarct Size in the Permanent Occlusion Model., PMID:38674000

Arginine alleviates Clostridium perfringens α toxin-induced intestinal injury in vivo and in vitro via the SLC38A9/mTORC1 pathway., PMID:38638435

Formononetin attenuates psoriasiform inflammation by regulating interferon signaling pathway., PMID:38579666

HIF-1α Mediates Immunosuppression and Chemoresistance in Colorectal Cancer by Inhibiting CXCL9, -10 and -11., PMID:38484558

Chemokines form complex signals during inflammation and disease that can be decoded by extracellular matrix proteoglycans., PMID:37934811

Biomarkers of ocular allergy and dry eye disease., PMID:37876509

CXCR3-CXCL11 signaling restricts angiogenesis and promotes pericyte recruitment., PMID:37745440

A Network Landscape of HPVOPC Reveals Methylation Alterations as Significant Drivers of Gene Expression via an Immune-Mediated GPCR Signal., PMID:37686653

Atlas of the anatomical localization of atypical chemokine receptors in healthy mice., PMID:37159457

Stem-like signatures in human meningioma cells are under the control of CXCL11/CXCL12 chemokine activity., PMID:37074930

EphA2 Promotes the Development of Cervical Cancer through the CXCL11/PD-L1 Pathway., PMID:36478746

The LINC00152/miR-205-5p/CXCL11 axis in hepatocellular carcinoma cancer-associated fibroblasts affects cancer cell phenotypes and tumor growth., PMID:36435866

GSK343, an Inhibitor of Enhancer of Zeste Homolog 2, Reduces Glioblastoma Progression through Inflammatory Process Modulation: Focus on Canonical and Non-Canonical NF-κB/IκBα Pathways., PMID:36430394

Identification of CXCL10 and CXCL11 as the candidate genes involving the development of colitis-associated colorectal cancer., PMID:36003333

Identification of Novel Therapeutic Candidates Against SARS-CoV-2 Infections: An Application of RNA Sequencing Toward mRNA Based Nanotherapeutics., PMID:35983322

Radiation combined with KRAS-MEK inhibitors enhances anticancer immunity in KRAS-mutated tumor models., PMID:35948200

Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine Receptor CXCR3 for Autoimmune Diseases., PMID:35947786

Circulating SSEA-1+ stem cell-mediated tissue repair in allergic airway inflammation., PMID:35670856

Integrative analysis identifies CXCL11 as an immune-related prognostic biomarker correlated with cell proliferation and immune infiltration in multiple myeloma microenvironment., PMID:35568859

Serpine1 Regulates Peripheral Neutrophil Recruitment and Acts as Potential Target in Ischemic Stroke., PMID:35494316

RAMP2-AS1 inhibits CXCL11 expression to suppress malignant phenotype of breast cancer by recruiting DNMT1 and DNMT3B., PMID:35390315

Epigenetic activation of RBM15 promotes clear cell renal cell carcinoma growth, metastasis and macrophage infiltration by regulating the m6A modification of CXCL11., PMID:35381326

CXCL11 expressing C57BL/6 mice have intact adaptive immune responses to viral infection., PMID:35233830

NOTCH2NLA silencing inhibits ovarian carcinoma progression and oncogenic activity in vivo and in vitro., PMID:34988178

A Combination of Glutaminase Inhibitor 968 and PD-L1 Blockade Boosts the Immune Response against Ovarian Cancer., PMID:34944392

Screening of CXC chemokines in the microenvironment of ovarian cancer and the biological function of CXCL10., PMID:34794429

Plasmacytoid dendritic cells promote the pathogenesis of Sjögren's syndrome., PMID:34780913

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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For research use only. Not for human or drug use.

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InVivoMAb Anti-Human CXCL11/I-TAC (Iv0089) [VHA24601]
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