Catalog No.
VHC01901
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Applications
ELISA, Neutralization
Target
Gamma-IP10, C-X-C motif chemokine 10, INP10, 10 kDa interferon gamma-induced protein, Small-inducible cytokine B10, SCYB10, IP-10, CXCL10
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P02778
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0088
Note
For research use only. Not suitable for clinical or therapeutic use.
Tomatidine relieves neuronal damage in spinal cord injury by inhibiting the inflammatory responses and apoptosis through blocking the NF-κB/CXCL10 pathway activation., PMID:39726790
Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanoma., PMID:39739311
LPS Disrupts Endometrial Receptivity by Inhibiting STAT1 Phosphorylation in Sheep., PMID:39769435
Nanostructured lipid carriers based mRNA vaccine leads to a T cell-inflamed tumour microenvironment favourable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumour model., PMID:39793480
MAF1 inhibits hepatocarcinogenesis by fostering an immunostimulatory tumor microenvironment., PMID:39800372
Peptidoglycan induces CXCL10 production and inhibits esophageal squamous cell carcinoma proliferation., PMID:39803645
Cepharanthine relieves nonalcoholic steatohepatitis through inhibiting STAT1/CXCL10 axis-mediated lipogenesis and inflammatory responses., PMID:39805479
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience., PMID:39827664
Transcriptome analysis of regenerated dermis stimulated by mechanical stretch., PMID:39842648
Role of CXCL10 released from osteocytes in response to TNF-α stimulation on osteoclasts., PMID:39856227
CircPRKD3-loaded exosomes concomitantly elicit tumor growth inhibition and glioblastoma microenvironment remodeling via inhibiting STAT3 signaling., PMID:39868921
Baicalein antagonises Rhopilema esculentum toxin-induced oxidative stress and apoptosis by modulating ROS-MAPK-NF-κB and inhibiting PLA2 activity., PMID:39880047
Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8+ T-cell antitumor activity via the non-canonical P53/STING pathway., PMID:39915005
Epidermal growth factor dampens pro-inflammatory gene expression induced by interferon-gamma in global transcriptome analysis of keratinocytes., PMID:39924511
Rutecarpine Suppresses Non-Small Cell Lung Cancer Progression Through Activating the STING Pathway and Elevating CD8+ T Cells., PMID:39989173
Fc-competent TIGITx4-1BB bispecific antibody exerts potent long-lasting antitumor activity by potentiating CD8+ T cell activity and Fcγ receptor-mediated modulation of the tumor microenvironment., PMID:40010766
Oral Lipid-Based Nanomedicine for the Inhibition of the cGAS-STING Pathway in Inflammatory Bowel Disease Treatment., PMID:40032274
IKZF1 and Ikaros Overexpression Results in Alopecia Areata-Like Phenotype in Mice., PMID:40066904
PBRM1 deficiency enhances PD1 immunotherapeutic sensitivity via chromosomal accessibility in colorectal cancer., PMID:40093909
RBM15, an m6A enzyme, suppresses NLRP3 inflammasome activation in rheumatoid arthritis through macrophage metabolism., PMID:40095631
[Lupeol Alleviates Chondrocytes Senescence in Osteoarthritis by Regulating Autophagy via the Sirtuin 3/Mechanistic Target of Rapamycin Kinase Pathway]., PMID:40109468
Upregulation of RIG-I is Critical for Responsiveness to IFN-α Plus Anti-PD-1 in Colorectal Cancer., PMID:40116486
Altered cytokine release of airway epithelial cells in vitro by combinations of respiratory syncytial virus, Streptococcus pneumoniae, Printex 90 and diesel exhaust particles., PMID:40118319
Melatonin Alleviates Behavioral and Neurodevelopmental Abnormalities in Offspring Caused by Prenatal Stress., PMID:40130458
Axl Regulation of NK Cell Activity Creates an Immunosuppressive Tumor Immune Microenvironment in Head and Neck Cancer., PMID:40149328
PAR2 deficiency impairs antitumor immunity and attenuates anti-PD1 efficacy in colorectal cancer., PMID:40174816
Harnessing immunotherapeutic molecules and diagnostic biomarkers as human-derived adjuvants for MERS-CoV vaccine development., PMID:40181980
Adjuvanticity of Tannic Acid-Modified Nanoparticles Improves Effectiveness of the Antiviral Response., PMID:40191045
The mechanism of EZH2/H3K27me3 downregulating CXCL10 to affect CD8+ T cell exhaustion to participate in the transformation from myelodysplastic syndrome to acute myeloid leukaemia., PMID:40201935
Defining neuronal responses to the neurotropic parasite Toxoplasma gondii., PMID:40236177
Enhanced renal ischemia/reperfusion injury repair potential of exosomes derived from B7-H1high mesenchymal stem cells., PMID:40242472
Ginsenoside Rh2 in combination with IFNγ potentiated the anti-cancer effect by enhancing interferon signaling response in colorectal cancer cells., PMID:40263567
Identification of Dinaciclib and Ganetespib as anti-inflammatory drugs using a novel HTP screening assay that targets IFNγ-dependent PD-L1., PMID:40264756
Selective BCL-2 inhibitor triggers STING-dependent antitumor immunity via inducing mtDNA release., PMID:40300857
Inhibition of MBTPS1 enhances antitumor immunity and potentiates anti-PD-1 immunotherapy., PMID:40307212
Thymoquinone enhances efficacy of cervical Cancer therapeutic vaccines via modulating CD8+ T cells., PMID:40316484
POSTN Silencing Ameliorates LL37-Induced Rosacea and Inhibits the JAK2/STAT3 and NF-κB Pathways., PMID:40387439
Reactivating cGAS-STING Signaling by Targeting SOS1 Enhances Antitumor Immunity in NRAS-Mutant Tumors., PMID:40392233
Unleashing anti-tumor immunity: Targeting the autophagy-related protein VPS34 to enhance STING agonist-based therapy., PMID:40395527
RSV-Induced Regulation of DC via H3K4 Demethylase KDM5b., PMID:40417973
Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-mediated Cytokine and Chemokine Production in Whole Blood in vitro., PMID:40435967
Defining neuronal responses to the neurotropic parasite Toxoplasma gondii., PMID:40444956
FGFR4 promotes CAF activation through the CXCL10-CXCR3 axis in colon cancer., PMID:40447617
In silico prediction of differentially expressed genes and functionally grouped networks in patients with inflamed pulp for screening pulpitis biomarkers., PMID:40453410
CXCL10highTNFαhighKi67+ Microglia Recruit and Activate CD8+ T Cells in the Brainstem During Experimental Cerebral Malaria., PMID:40457525
The role of immune checkpoint molecules in PRRSV-2-induced immune modulation: insights from comparative in vivo evaluation including NADC34-like PRRSV., PMID:40459260
Integrated profiling of adiponectin and cytokine signaling pathways in high-fat diet-induced MASLD reveals early markers of disease progression., PMID:40467680
Alkaline Treatment Enhances the Anti-inflammatory and Reparative Potential of Dentin Matrix Proteins in Inflamed Pulp., PMID:40484223
The metastatic role of the CXCL10-CXCR3 axis and its therapeutic potential in osteosarcoma., PMID:40502679
Gene signature-guided isolation identifies cucurbitacins as STAT3 inhibitors from Picria fel-terrae Lour., PMID:40505486
For research use only. Not for human or drug use.
