Catalog No.
VHC01901
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Gamma-IP10, C-X-C motif chemokine 10, INP10, 10 kDa interferon gamma-induced protein, Small-inducible cytokine B10, SCYB10, IP-10, CXCL10
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P02778
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0088
Gene signature-guided isolation identifies cucurbitacins as STAT3 inhibitors from Picria fel-terrae Lour., PMID:40505486
The metastatic role of the CXCL10-CXCR3 axis and its therapeutic potential in osteosarcoma., PMID:40502679
Alkaline Treatment Enhances the Anti-inflammatory and Reparative Potential of Dentin Matrix Proteins in Inflamed Pulp., PMID:40484223
Integrated profiling of adiponectin and cytokine signaling pathways in high-fat diet-induced MASLD reveals early markers of disease progression., PMID:40467680
The role of immune checkpoint molecules in PRRSV-2-induced immune modulation: insights from comparative in vivo evaluation including NADC34-like PRRSV., PMID:40459260
CXCL10highTNFαhighKi67+ Microglia Recruit and Activate CD8+ T Cells in the Brainstem During Experimental Cerebral Malaria., PMID:40457525
In silico prediction of differentially expressed genes and functionally grouped networks in patients with inflamed pulp for screening pulpitis biomarkers., PMID:40453410
FGFR4 promotes CAF activation through the CXCL10-CXCR3 axis in colon cancer., PMID:40447617
Defining neuronal responses to the neurotropic parasite Toxoplasma gondii., PMID:40444956
Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-mediated Cytokine and Chemokine Production in Whole Blood in vitro., PMID:40435967
RSV-Induced Regulation of DC via H3K4 Demethylase KDM5b., PMID:40417973
Unleashing anti-tumor immunity: Targeting the autophagy-related protein VPS34 to enhance STING agonist-based therapy., PMID:40395527
Reactivating cGAS-STING Signaling by Targeting SOS1 Enhances Antitumor Immunity in NRAS-Mutant Tumors., PMID:40392233
POSTN Silencing Ameliorates LL37-Induced Rosacea and Inhibits the JAK2/STAT3 and NF-κB Pathways., PMID:40387439
Thymoquinone enhances efficacy of cervical Cancer therapeutic vaccines via modulating CD8+ T cells., PMID:40316484
Inhibition of MBTPS1 enhances antitumor immunity and potentiates anti-PD-1 immunotherapy., PMID:40307212
Selective BCL-2 inhibitor triggers STING-dependent antitumor immunity via inducing mtDNA release., PMID:40300857
Identification of Dinaciclib and Ganetespib as anti-inflammatory drugs using a novel HTP screening assay that targets IFNγ-dependent PD-L1., PMID:40264756
Ginsenoside Rh2 in combination with IFNγ potentiated the anti-cancer effect by enhancing interferon signaling response in colorectal cancer cells., PMID:40263567
Enhanced renal ischemia/reperfusion injury repair potential of exosomes derived from B7-H1high mesenchymal stem cells., PMID:40242472
Defining neuronal responses to the neurotropic parasite Toxoplasma gondii., PMID:40236177
The mechanism of EZH2/H3K27me3 downregulating CXCL10 to affect CD8+ T cell exhaustion to participate in the transformation from myelodysplastic syndrome to acute myeloid leukaemia., PMID:40201935
Adjuvanticity of Tannic Acid-Modified Nanoparticles Improves Effectiveness of the Antiviral Response., PMID:40191045
Harnessing immunotherapeutic molecules and diagnostic biomarkers as human-derived adjuvants for MERS-CoV vaccine development., PMID:40181980
PAR2 deficiency impairs antitumor immunity and attenuates anti-PD1 efficacy in colorectal cancer., PMID:40174816
Axl Regulation of NK Cell Activity Creates an Immunosuppressive Tumor Immune Microenvironment in Head and Neck Cancer., PMID:40149328
Melatonin Alleviates Behavioral and Neurodevelopmental Abnormalities in Offspring Caused by Prenatal Stress., PMID:40130458
Altered cytokine release of airway epithelial cells in vitro by combinations of respiratory syncytial virus, Streptococcus pneumoniae, Printex 90 and diesel exhaust particles., PMID:40118319
Upregulation of RIG-I is Critical for Responsiveness to IFN-α Plus Anti-PD-1 in Colorectal Cancer., PMID:40116486
[Lupeol Alleviates Chondrocytes Senescence in Osteoarthritis by Regulating Autophagy via the Sirtuin 3/Mechanistic Target of Rapamycin Kinase Pathway]., PMID:40109468
RBM15, an m6A enzyme, suppresses NLRP3 inflammasome activation in rheumatoid arthritis through macrophage metabolism., PMID:40095631
PBRM1 deficiency enhances PD1 immunotherapeutic sensitivity via chromosomal accessibility in colorectal cancer., PMID:40093909
IKZF1 and Ikaros Overexpression Results in Alopecia Areata-Like Phenotype in Mice., PMID:40066904
Oral Lipid-Based Nanomedicine for the Inhibition of the cGAS-STING Pathway in Inflammatory Bowel Disease Treatment., PMID:40032274
Fc-competent TIGITx4-1BB bispecific antibody exerts potent long-lasting antitumor activity by potentiating CD8+ T cell activity and Fcγ receptor-mediated modulation of the tumor microenvironment., PMID:40010766
Rutecarpine Suppresses Non-Small Cell Lung Cancer Progression Through Activating the STING Pathway and Elevating CD8+ T Cells., PMID:39989173
Epidermal growth factor dampens pro-inflammatory gene expression induced by interferon-gamma in global transcriptome analysis of keratinocytes., PMID:39924511
Clofarabine induces tumor cell apoptosis, GSDME-related pyroptosis, and CD8+ T-cell antitumor activity via the non-canonical P53/STING pathway., PMID:39915005
Baicalein antagonises Rhopilema esculentum toxin-induced oxidative stress and apoptosis by modulating ROS-MAPK-NF-κB and inhibiting PLA2 activity., PMID:39880047
CircPRKD3-loaded exosomes concomitantly elicit tumor growth inhibition and glioblastoma microenvironment remodeling via inhibiting STAT3 signaling., PMID:39868921
Role of CXCL10 released from osteocytes in response to TNF-α stimulation on osteoclasts., PMID:39856227
Transcriptome analysis of regenerated dermis stimulated by mechanical stretch., PMID:39842648
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience., PMID:39827664
Cepharanthine relieves nonalcoholic steatohepatitis through inhibiting STAT1/CXCL10 axis-mediated lipogenesis and inflammatory responses., PMID:39805479
Peptidoglycan induces CXCL10 production and inhibits esophageal squamous cell carcinoma proliferation., PMID:39803645
MAF1 inhibits hepatocarcinogenesis by fostering an immunostimulatory tumor microenvironment., PMID:39800372
Nanostructured lipid carriers based mRNA vaccine leads to a T cell-inflamed tumour microenvironment favourable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumour model., PMID:39793480
LPS Disrupts Endometrial Receptivity by Inhibiting STAT1 Phosphorylation in Sheep., PMID:39769435
Spatial proteomics reveals sirtuin 1 to be a determinant of T-cell infiltration in human melanoma., PMID:39739311
Tomatidine relieves neuronal damage in spinal cord injury by inhibiting the inflammatory responses and apoptosis through blocking the NF-κB/CXCL10 pathway activation., PMID:39726790
For research use only. Not for human or drug use.
