Catalog No.
VHF70301
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Monocyte chemoattractant protein 2, Small-inducible cytokine A8, HC14, C-C motif chemokine 8, SCYA10, MCP2, SCYA8, CCL8, Monocyte chemotactic protein 2, MCP-2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P80075
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0080
The role of immune checkpoint molecules in PRRSV-2-induced immune modulation: insights from comparative in vivo evaluation including NADC34-like PRRSV., PMID:40459260
Modulation of Macrophages TLR4-Mediated Transcriptional Response by Lacticaseibacillus rhamnosus CRL1505 and Lactiplantibacillus plantarum CRL1506., PMID:40141330
Tumor-initiating cells escape tumor immunity via CCL8 from tumor-associated macrophages in mice., PMID:39774471
Tryptophan 2,3-dioxygenase-positive matrix fibroblasts fuel breast cancer lung metastasis via kynurenine-mediated ferroptosis resistance of metastatic cells and T cell dysfunction., PMID:39221971
Muscle cell-derived Ccl8 is a negative regulator of skeletal muscle regeneration., PMID:39051762
Monocytes expressing activin A and CCR2 exacerbate chronic testicular inflammation by promoting immune cell infiltration., PMID:38775335
Chemokine profiling of melanoma-macrophage crosstalk identifies CCL8 and CCL15 as prognostic factors in cutaneous melanoma., PMID:38287901
Lactate-Induced CCL8 in Tumor-Associated Macrophages Accelerates the Progression of Colorectal Cancer through the CCL8/CCR5/mTORC1 Axis., PMID:38136340
Fasting mimicking diet inhibits tumor-associated macrophage survival and pro-tumor function in hypoxia: implications for combination therapy with anti-angiogenic agent., PMID:37884960
APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN., PMID:37305534
Inflammatory chemokine (C-C motif) ligand 8 inhibition ameliorates peritoneal fibrosis., PMID:36468785
Culture of endometrial epithelial cells collected by a cytological brush in vivo., PMID:36338819
Deficiency of eIF4B Increases Mouse Mortality and Impairs Antiviral Immunity., PMID:34566982
Lenvatinib enhances T cell immunity and the efficacy of adoptive chimeric antigen receptor-modified T cells by decreasing myeloid-derived suppressor cells in cancer., PMID:34411731
CCL8 mediates crosstalk between endothelial colony forming cells and triple-negative breast cancer cells through IL-8, aggravating invasion and tumorigenicity., PMID:33833397
A Glucuronic Acid-Palmitoylethanolamide Conjugate (GLUPEA) Is an Innovative Drug Delivery System and a Potential Bioregulator., PMID:33672574
Airway macrophage-intrinsic TGF-β1 regulates pulmonary immunity during early-life allergen exposure., PMID:33571538
Asymptomatic Infection of Marburg Virus Reservoir Bats Is Explained by a Strategy of Immunoprotective Disease Tolerance., PMID:33157026
Immunobiotic Lactobacillus jensenii TL2937 Alleviates Dextran Sodium Sulfate-Induced Colitis by Differentially Modulating the Transcriptomic Response of Intestinal Epithelial Cells., PMID:33042131
C-C Motif Chemokine 8 promotes angiogenesis in vascular endothelial cells., PMID:32972333
Possible involvement of crosstalk between endometrial cells and mast cells in the development of endometriosis via CCL8/CCR1., PMID:32768961
Engineered anti-inflammatory peptides inspired by mapping an evasin-chemokine interaction., PMID:32471866
Alterations of peripheral gene expression in response to lipopolysaccharide-induced synovitis as a model for inflammation in horses., PMID:32442811
Responses of serum chemokines to dramatic changes of air pollution levels, a panel study., PMID:31456427
Weighted gene correlation network analysis identifies RSAD2, HERC5, and CCL8 as prognostic candidates for breast cancer., PMID:31225658
Elafibranor restricts lipogenic and inflammatory responses in a human skin stem cell-derived model of NASH., PMID:31028903
CCL8 enhances sensitivity of cutaneous squamous cell carcinoma to photodynamic therapy by recruiting M1 macrophages., PMID:30902794
Effect of freeze-dried Carica papaya leaf juice on inflammatory cytokines production during dengue virus infection in AG129 mice., PMID:30744623
MicroRNA-146a-5p attenuates visceral hypersensitivity through targeting chemokine CCL8 in the spinal cord in a mouse model of colitis., PMID:29550454
Nicaraven reduces cancer metastasis to irradiated lungs by decreasing CCL8 and macrophage recruitment., PMID:29339207
Functional expression of CCL8 and its interaction with chemokine receptor CCR3., PMID:29281969
Mesenchymal Stem Cells (MSCs) Attenuate Cutaneous Sclerodermatous Graft-Versus-Host Disease (Scl-GVHD) through Inhibition of Immune Cell Infiltration in a Mouse Model., PMID:28526296
Induction of the MCP chemokine cluster cascade in the periphery by cancer cell-derived Ccl3., PMID:28041977
High-concentrate feeding upregulates the expression of inflammation-related genes in the ruminal epithelium of dairy cattle., PMID:27478614
Infiltration of myeloid cells in the pregnant uterus is affected by heme oxygenase-1., PMID:27468759
E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis., PMID:26956647
The role of FGF2 in migration and tubulogenesis of endothelial progenitor cells in relation to pro-angiogenic growth factor production., PMID:26314253
Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts., PMID:26093063
Selenium analogues of raloxifene as promising antiproliferative agents in treatment of breast cancer., PMID:25282270
MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes., PMID:24996260
Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner., PMID:24958709
Effect of erythropoietin on primed leucocyte expression profile., PMID:24920275
In vitro test system for evaluation of immune activation potential of new single-stranded DNA-based therapeutics., PMID:24817283
Effects of IL8 and immune cells on the regulation of luteal progesterone secretion., PMID:24686456
System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity., PMID:24068959
Potential capacity of aptamers to trigger immune activation in human blood., PMID:23935890
Characterization of regulatory dendritic cells differentiated from the bone marrow of UV-irradiated mice., PMID:23826713
The chemokine receptor CCR3 participates in tissue remodeling during atopic skin inflammation., PMID:23702389
Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation., PMID:23585676
Chemokine expression is upregulated in chondrocytes in diabetic fracture healing., PMID:23262028
For research use only. Not for human or drug use.
