Catalog No.
VHB91501
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
ETGF, Protransforming growth factor alpha, TGF type 1, TGFA, EGF-like TGF, TGF-alpha
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P01135
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0068
An antibody-drug conjugate targeting soluble and membrane-bound TGFα is effective against pancreatic tumors., PMID:40410803
Secretion of WNT7A by UC-MSCs assist in promoting the endometrial epithelial regeneration., PMID:38947517
CircRTN1 acts as a miR-431-5p sponge to promote thyroid cancer progression by upregulating TGFA., PMID:35804263
Circular RNA TAF4B Promotes Bladder Cancer Progression by Sponging miR-1298-5p and Regulating TGFA Expression., PMID:34322376
MicroRNA-374b inhibits breast cancer progression through regulating CCND1 and TGFA genes., PMID:33480984
Keratinocyte autophagy enables the activation of keratinocytes and fibroblastsand facilitates wound healing., PMID:32866426
An EGFR ligand promotes EGFR-mutant but not KRAS-mutant lung cancer in vivo., PMID:29662194
Hypoxia-Preconditioned Human Umbilical Vein Endothelial Cells Protect Against Neurovascular Damage After Hypoxic Ischemia in Neonatal Brain., PMID:29460267
Role of TGF-alpha in the progression of diabetic kidney disease., PMID:28249836
Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia., PMID:27633013
ADAM17 is a Tumor Promoter and Therapeutic Target in Western Diet-associated Colon Cancer., PMID:27489286
Context-specific protection of TGFα null mice from osteoarthritis., PMID:27457421
MicroRNA-505 functions as a tumor suppressor in endometrial cancer by targeting TGF-α., PMID:26832151
Generation of stomach tissue from mouse embryonic stem cells., PMID:26192439
Reduction in disease progression by inhibition of transforming growth factor α-CCL2 signaling in experimental posttraumatic osteoarthritis., PMID:26138996
Influence of Cancer-Associated Endometrial Stromal Cells on Hormone-Driven Endometrial Tumor Growth., PMID:25976290
Transforming growth factor alpha promotes osteosarcoma metastasis by ICAM-1 and PI3K/Akt signaling pathway., PMID:24685520
Generation and activity of a humanized monoclonal antibody that selectively neutralizes the epidermal growth factor receptor ligands transforming growth factor-α and epiregulin., PMID:24518034
Signal peptidase complex 18, encoded by SEC11A, contributes to progression via TGF-α secretion in gastric cancer., PMID:23995782
Myogenic lineage differentiated mesenchymal stem cells enhance recovery from dextran sulfate sodium-induced colitis in the rat., PMID:20848145
TGF-beta inactivation and TGF-alpha overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancer., PMID:20020490
Induction of angiogenesis by normal and malignant plasma cells., PMID:19299335
Gene expression profiling of human neural progenitor cells following the serum-induced astrocyte differentiation., PMID:19130216
Tumor necrosis factor regulation of apoptosis in mouse preimplantation embryos and its antagonism by transforming growth factor alpha/phosphatidylionsitol 3-kinase signaling system., PMID:17182889
Endocrine pancreatic tissue plasticity in obese humans is associated with cytoplasmic expression of PBX-1 in pancreatic ductal cells., PMID:15979049
Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor., PMID:15366372
Biological properties and gene expression associated with metastatic potential of human osteosarcoma., PMID:14669798
Comparison of the antisecretory and antiulcer activity of epidermal growth factor, urogastrone and transforming growth factor alpha and its derivative in rodents in vivo., PMID:12190125
The rationale and strategy used to develop a series of highly potent, irreversible, inhibitors of the epidermal growth factor receptor family of tyrosine kinases., PMID:10495354
Measurement of human lipogenesis using deuterium incorporation., PMID:8383169
Effect of a high-fat diet on the incorporation of stored triacylglycerol into hepatic VLDL., PMID:1415680
Effects of diet and exercise on the in vivo rates of the triglyceride-fatty acid cycle in adipose tissue and muscle of the rat., PMID:2276857
Secretion and storage of newly synthesized hepatic triacylglycerol fatty acids in vivo in different nutritional states and in diabetes., PMID:3214432
Quantitative studies on the fetal lipid metabolism in rats: liver fatty acid esterification and conversion into carbon dioxide, and hepatic output of triglycerides and phospholipids into serum., PMID:3081053
Adipocyte fatty acid mobilization in vivo: effects of age and anatomical location., PMID:4010482
In vivo tracer studies of perturbed fatty acid transport and metabolism in adipose tissue., PMID:4066121
Endogenous triacylglycerol metabolism in diabetic heart., PMID:7091348
Fatty acid synthesis in vivo and hepatic contribution to whole-body lipogenic rates in obese Zucker rats., PMID:7219075
The mobilization of free fatty acids in relation to adipose tissue triglyceride fatty acids in the rat., PMID:5441252
For research use only. Not for human or drug use.
