Catalog No.
FHC97810
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
HC11, MCP-1, MCP1, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, Small-inducible cytokine A2, SCYA2, MCAF, Monocyte secretory protein JE, C-C motif chemokine 2, Monocyte chemoattractant protein 1, CCL2
Concentration
1.07 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P13500
Applications
Blocking, ELISA, FCM
Form
Liquid
Storage buffer
PBS, pH 6.0, 0.2M Arg
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
11k2
The dichotomous impacts of Semaphorin3E deficiency on exacerbating airway hyperresponsiveness, remodelling, and inflammation in type-2 low and type-2 high asthma models., PMID:40512736
Monoclonal Antibodies to Thyrotropin Receptor With Thyroid-Stimulating Activity Activate the NF-κB Pathway to Induce Chemokine Expression., PMID:40500868
Selected cytokine and chemokine concentrations in equine autologous conditioned serum are similar under defined and practically relevant storage conditions., PMID:40496923
Myeloid Glutamine Synthetase Protects Against Acute Liver Injury in Mice Independent of Its Enzyme Activity., PMID:40485395
Prolactin promotes transepithelial migration of lymphocytes through CCL2., PMID:40446683
Inhibition of MCP1 (CCL2) Enhances Antitumor Activity of NK Cells Against HCC Cells Under Hypoxia., PMID:40430040
Di(2-ethylhexyl) Phthalate (DEHP) Exacerbates Food Allergy via Intestinal Barrier Dysfunction and Enhancing Allergic Sensitization., PMID:40396676
Osteosarcoma cell-derived CCL2 facilitates lung metastasis via accumulation of tumor-associated macrophages., PMID:40343498
LPS-induced extracellular AREG triggers macrophage pyroptosis through the EGFR/TLR4 signaling pathway., PMID:40292295
NAT10 exacerbates acute renal inflammation by enhancing N4-acetylcytidine modification of the CCL2/CXCL1 axis., PMID:40261924
[Effect of Evodiamine on immune function of allergic rhinitis rats by regulating CCL2/CCR2 signaling pathway]., PMID:40260562
APOC1 expressed in macrophages promotes the pulmonary metastasis of colorectal cancer via CCL2/CCL5., PMID:40194454
Pancreatic cancer extracellular vesicles stimulate Schwann cell activation and perineural invasion in vitro via IL-8/CCL2., PMID:40160208
The TMBIM1-YBX1 axis orchestrates MDSC recruitment and immunosuppressive microenvironment in pancreatic cancer., PMID:40083936
Exploratory analyses of leukocyte responses in hospitalized patients treated with ozanimod following a severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infection., PMID:40025871
Autoantibody Profiles and Prognostic Significance in Severe Fever With Thrombocytopenia Syndrome (SFTS) Patients., PMID:39995275
Lung-delivered IL-10 mitigates Lung inflammation induced by repeated endotoxin exposures in male mice., PMID:39980189
Evaluation of a nanoparticle influenza vaccine in the pig model., PMID:39947075
Human hypofunctional NCF1 variants promote pulmonary fibrosis in the bleomycin-induced mouse model and patients with systemic sclerosis via expansion of SPP1+ monocytes-derived macrophages., PMID:39919902
YAP/TAZ are crucial regulators of macrophage-mediated pulmonary inflammation and fibrosis after bleomycin-induced injury., PMID:39915054
Rapid, Sensitive Detection of Protein Biomarkers in Minimally-Processed Blood Products with a Monolithic Sandwich Immunoassay Reagent., PMID:39910829
The lactate receptor HCAR1 drives the recruitment of immunosuppressive PMN-MDSCs in colorectal cancer., PMID:39905201
Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19., PMID:39896810
Monocytes and interstitial macrophages contribute to hypoxic pulmonary hypertension., PMID:39883518
Suppression of MCP-1, IFN-γ and IL-6 production of HNSCC ex vivo by pembrolizumab added to docetaxel and cisplatin (TP) exceeding those of TP alone is linked to improved survival., PMID:39882242
Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome., PMID:39871175
Bifidobacterium longum RAPO Attenuates Dermal and Pulmonary Fibrosis in a Mouse Model of Systemic Sclerosis through Macrophage Modulation and Growth of Short-Chain Fatty Acid Producers., PMID:39801739
PDPN+ cancer-associated fibroblasts enhance gastric cancer angiogenesis via AKT/NF-κB activation and the CCL2-ACKR1 axis., PMID:39764562
Group B Streptococcal Membrane Vesicles Induce Proinflammatory Cytokine Production and Are Sensed in an NLRP3 Inflammasome-Dependent Mechanism in a Human Macrophage-like Cell Line., PMID:39761308
Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor binding., PMID:39753140
Effects of linsitinib on M22 and IGF:1-treated 3D spheroids of human orbital fibroblasts., PMID:39747159
Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) drives abnormal pericyte-rich vasculature in triple-negative breast cancer., PMID:39636369
High throughput multiplex immunoassays stratify patients according to symptom burden across the anti-Ro positive systemic autoimmune rheumatic disease spectrum., PMID:39606818
Serum Concentrations of Pro- and Anti-Inflammatory Cytokines in Wistar Rats Subjected to Immobilization Stress and Treated with Tuftsin-Pro-Gly-Pro Peptide., PMID:39565500
Regulatory T cells require peripheral CCL2-CCR2 signaling to facilitate the resolution of medication overuse headache-related behavioral sensitization., PMID:39528947
Cytokine profile of cerebrospinal fluid in pediatric patients with metastatic medulloblastoma., PMID:39524698
Inhibition of Bruton's tyrosine kinase with PD-1 blockade modulates T cell activation in solid tumors., PMID:39513363
Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells., PMID:39484394
A human tissue-based model of renal inflammation., PMID:39476943
Ageing-Related Macrophage Polarisation in the Trigeminal Ganglion Enhances Incisional Intraoral Pain., PMID:39467109
Increased Cytokine Levels in Seronegative Myositis: Potential Th17 Immune Response Implications., PMID:39456842
Molecular mechanism of IgE-mediated FcεRI activation., PMID:39442557
Lipocalin-2 Serum Levels in Rheumatoid Arthritis Patients Treated with Adalimumab and Its Correlation with Proinflammatory Factors., PMID:39403549
Examining the Relationship Between Polystyrene Microplastics and Male Fertility: Insights From an In Vivo Study and In Vitro Sertoli Cell Culture., PMID:39376189
DDIAS Regulation of STAT3/CCL2 Promotes Macrophage Polarization to M1 type in Kawasaki Disease., PMID:39293834
Predictive biomarkers of mortality in patients with severe COVID-19 hospitalized in intensive care unit., PMID:39281667
In vitro analysis of VEGF-mediated endothelial permeability and the potential therapeutic role of Anti-VEGF in severe dengue., PMID:39263317
NK/DC crosstalk-modulating antitumor activity via Sema3E/PlexinD1 axis for enhanced cancer immunotherapy., PMID:39235526
Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival., PMID:39232121
CpG oligonucleotides induce acute murine thrombocytopenia dependent on toll-like receptor 9 and spleen tyrosine kinase pathways., PMID:39155024
For research use only. Not for human or drug use.
