Soluble CD27 differentially predicts resistance to anti-PD1 alone but not with anti-CTLA-4 in melanoma., PMID:40148586
High Antigenicity for Treg Cells Confers Resistance to PD-1 Blockade Therapy via High PD-1 Expression in Treg Cells., PMID:40017103
First-in-human evaluation of memory-like NK cells with an IL-15 super-agonist and CTLA-4 blockade in advanced head and neck cancer., PMID:39948608
Congenital T-cell activation impairs transitional-to-follicular B-cell maturation in humans., PMID:39626280
CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner., PMID:39496592
Analysis of Expression Pattern and Prognostic Value of the Heparanase in Breast Cancer Through CD274/CTLA-4 Immune Checkpoint Proteins., PMID:39248214
Design a novel of Brucellosis preventive vaccine based on IgV_CTLA-4 and multiple epitopes via immunoinformatics approach., PMID:39218373
Preclinical development of a novel CCR8/CTLA-4 bispecific antibody for cancer treatment by disrupting CTLA-4 signaling on CD8 T cells and specifically depleting tumor-resident Tregs., PMID:39123089
Targeting exhausted cytotoxic T cells through CTLA-4 inhibition promotes elimination of neoplastic cells in human myelofibrosis xenografts., PMID:38953347
Antitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4., PMID:38806619
Granulocyte-Macrophage-Colony-Stimulating-Factor Combined with Prostaglandin E1 Create Dendritic Cells of Leukemic Origin from AML Patients' Whole Blood and Whole Bone Marrow That Mediate Antileukemic Processes after Mixed Lymphocyte Culture., PMID:38139264
Alteration of Immunoregulatory Patterns and Survival Advantage of Key Cell Types in Food Allergic Children., PMID:38067164
Mn-Anti-CTLA4-CREKA-Sericin Nanotheragnostics for Enhanced Magnetic Resonance Imaging and Tumor Immunotherapy., PMID:38009480
The OX40-TRAF6 axis promotes CTLA-4 degradation to augment antitumor CD8+ T-cell immunity., PMID:37932534
Faecalibacterium prausnitzii Abrogates Intestinal Toxicity and Promotes Tumor Immunity to Increase the Efficacy of Dual CTLA4 and PD-1 Checkpoint Blockade., PMID:37602831
Contriving a novel of CHB therapeutic vaccine based on IgV_CTLA-4 and L protein via immunoinformatics approach., PMID:37424209
CTLA4-Ig protects tacrolimus-induced oxidative stress via inhibiting the AKT/FOXO3 signaling pathway in rats., PMID:37157174
[Expression and Significance of PD-1, PD-L1 and CTLA-4 in the Bone Marrow of Patients with Multiple Myeloma]., PMID:36476907
Molecular and Functional Analyses of the Primordial Costimulatory Molecule CD80/86 and Its Receptors CD28 and CD152 (CTLA-4) in a Teleost Fish., PMID:35784316
Control of Memory Phenotype T Lymphocyte Homeostasis: Role of Costimulation., PMID:35039334
Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cells., PMID:35017553
Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells., PMID:35003894
Development of a fully canine anti-canine CTLA4 monoclonal antibody for comparative translational research in dogs with spontaneous tumors., PMID:34856888
Colon cancer cells acquire immune regulatory molecules from tumor-infiltrating lymphocytes by trogocytosis., PMID:34819374
A CTLA-4 blocking strategy based on Nanoboby in dendritic cell-stimulated cytokine-induced killer cells enhances their anti-tumor effects., PMID:34525966
Engineering a Smart Agent for Enhanced Immunotherapy Effect by Simultaneously Blocking PD-L1 and CTLA-4., PMID:34473430
Phytochemicals in Cancer Immune Checkpoint Inhibitor Therapy., PMID:34439774
In Vivo Induction of Regulatory T Cells Via CTLA-4 Signaling Peptide to Control Autoimmune Encephalomyelitis and Prevent Disease Relapse., PMID:34306974
Zearalenone and deoxynivalenol reduced Th1-mediated cellular immune response after Listeria monocytogenes infection by inhibiting CD4+ T cell activation and differentiation., PMID:34261220
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma., PMID:34083417
Cytotoxic T-lymphocyte Antigen-4 (CTLA-4) Gene Polymorphism (rs3087243) Is Related to Risk and Survival in Patients With Colorectal Cancer., PMID:33622891
Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1+ Activated T Cells., PMID:33419761
Activity of murine surrogate antibodies for durvalumab and tremelimumab lacking effector function and the ability to deplete regulatory T cells in mouse models of cancer., PMID:33397194
A short course of tofacitinib sustains the immunoregulatory effect of CTLA4-Ig in the presence of inflammatory cytokines and promotes long-term survival of murine cardiac allografts., PMID:33331121
IL-7/αIL-7 mAb M25 immunocomplexes expand CD8+ T cells but paradoxically abrogate the antitumor activity of CTLA-4 and PD-1 blockage., PMID:32599539
Pickering emulsions with ethiodized oil and nanoparticles for slow release of intratumoral anti-CTLA4 immune checkpoint antibodies., PMID:32571995
The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation., PMID:30975201
By Binding CD80 and CD86, the Vaccinia Virus M2 Protein Blocks Their Interactions with both CD28 and CTLA4 and Potentiates CD80 Binding to PD-L1., PMID:30918073
Leukemic B Cell CTLA-4 Suppresses Costimulation of T Cells., PMID:30910862
FcγR-Binding Is an Important Functional Attribute for Immune Checkpoint Antibodies in Cancer Immunotherapy., PMID:30863404
Disruption of CTLA-4 expression on peripheral blood CD8 + T cell enhances anti-tumor efficacy in bladder cancer., PMID:30848330
The role of FOXP3+ regulatory T cells in human autoimmune and inflammatory diseases., PMID:30830965
Immunophenotypic characterization of sphere-forming cells derived from the human renal cell carcinoma cell line 786-O., PMID:30662644
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody., PMID:30587582
A Pilot Trial of the Combination of Transgenic NY-ESO-1-reactive Adoptive Cellular Therapy with Dendritic Cell Vaccination with or without Ipilimumab., PMID:30573690
Low-dose chidamide restores immune tolerance in ITP in mice and humans., PMID:30552097
A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease., PMID:30446251
Radiotherapy induces responses of lung cancer to CTLA-4 blockade., PMID:30397353
Tumour cell-intrinsic CTLA4 regulates PD-L1 expression in non-small cell lung cancer., PMID:30378264
Synthetic DNA-Encoded Monoclonal Antibody Delivery of Anti-CTLA-4 Antibodies Induces Tumor Shrinkage In Vivo., PMID:30287678
For research use only. Not for human or drug use.
