Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Axatilimab in Healthy Japanese Male Participants: Results from a Phase 1, Randomized, Double-Blind, Dose-Escalation Study., PMID:40381116
New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma., PMID:40101804
Integration and functionality of human iPSC-derived microglia in a chimeric mouse retinal model., PMID:40016767
Development of antigen-capture enzyme-linked immunoassay for Chicken Interleukin-34., PMID:39900196
Is there a relationship between CSF Interleukin 34 Level and clinicoradiological activity and IgG index in patients with MS?, PMID:39571220
AKAP12 positive fibroblast determines immunosuppressive contexture and immunotherapy response in patients with TNBC by promoting macrophage M2 polarization., PMID:39448199
Profiles of cytokines in patients with antineutrophil cytoplasmic antibody-associated vasculitis., PMID:39108259
Knockout of integrin αvβ6 protects against renal inflammation in chronic kidney disease by reduction of pro-inflammatory macrophages., PMID:38844455
Serum interleukin-34 levels in dermatomyositis: a potential biomarker for anti-MDA5-antibody-associated interstitial lung disease., PMID:38830088
CSF-1R in Cancer: More than a Myeloid Cell Receptor., PMID:38254773
Validation of CSF-1 receptor (CD115) staining for analysis of murine monocytes by flow cytometry., PMID:38038378
Effects of IL-34 and anti-IL-34 neutralizing mAb on alveolar bone loss in a ligature-induced model of periodontitis., PMID:37902168
Genetic and Immunohistochemistry Tools to Visualize Rat Macrophages In Situ., PMID:37639117
Significance of IL-34 and SDC-1 in the pathogenesis of RA cells and preclinical models., PMID:37150238
Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3., PMID:36252111
Tumor-derived interleukin-34 creates an immunosuppressive and chemoresistant tumor microenvironment by modulating myeloid-derived suppressor cells in triple-negative breast cancer., PMID:36104597
IL-34 deficiency impairs FOXP3+ Treg function in a model of autoimmune colitis and decreases immune tolerance homeostasis., PMID:36030499
CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation., PMID:35353625
Pancreatic Ductal Adenocarcinoma (PDAC) circulating tumor cells influence myeloid cell differentiation to support their survival and immunoresistance in portal vein circulation., PMID:35316296
Analysis of phagocytosis by mIgM+ lymphocytes depending on monoclonal antibodies against IgM of largemouth bass (Micropterus salmoides)., PMID:35314332
Clinical evaluation of colony-stimulating factor 1 receptor inhibitors., PMID:34776301
[Interleukin-34: a key molecule in the tumor microenvironment]., PMID:34497220
An optimized protocol for patient-derived xenograft in humanized mice to evaluate the role of IL-34 in immunotherapeutic resistance., PMID:33899027
LY3022855, an anti-colony stimulating factor-1 receptor (CSF-1R) monoclonal antibody, in patients with advanced solid tumors refractory to standard therapy: phase 1 dose-escalation trial., PMID:33624233
Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice., PMID:33428678
Interleukin-34 Limits the Therapeutic Effects of Immune Checkpoint Blockade., PMID:33205010
Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration., PMID:33162994
Impact of IL-34, IFN-α and IFN-λ1 on activity of systemic lupus erythematosus in Egyptian patients., PMID:32921829
The M-CSF receptor in osteoclasts and beyond., PMID:32801364
C-reactive protein at 1 month after treatment of nivolumab as a predictive marker of efficacy in advanced renal cell carcinoma., PMID:32537714
Interleukin-34 as a marker for subclinical proliferative lupus nephritis., PMID:32237962
Interleukin 34 Serves as a Novel Molecular Adjuvant against Nocardia Seriolae Infection in Largemouth Bass (Micropterus Salmoides)., PMID:32231137
Elevated serum interleukin-34 level in juvenile systemic lupus erythematosus and disease activity., PMID:31907692
Interleukin-34 expression in ovarian cancer: a possible correlation with disease progression., PMID:31868884
Serum levels of interleukin-34 and clinical correlation in patients with primary Sjögren's syndrome., PMID:31823505
Prognostic value of IL-34 in colorectal cancer patients., PMID:31762401
Autocrine Production of Interleukin-34 Promotes the Development of Endometriosis through CSF1R/JAK3/STAT6 signaling., PMID:31727934
Protective effects of seaweed supplemented diet on antioxidant and immune responses in European seabass (Dicentrarchus labrax) subjected to bacterial infection., PMID:31695116
CSF1R Ligands IL-34 and CSF1 Are Differentially Required for Microglia Development and Maintenance in White and Gray Matter Brain Regions., PMID:31616414
Effect of Interleukin-34 on Secretion of Angiogenesis Cytokines by Peripheral Blood Mononuclear Cells of Rheumatoid Arthritis., PMID:31401905
Interleukin-34 as a promising clinical biomarker and therapeutic target for inflammatory arthritis., PMID:31126875
A role for IL-34 in osteolytic disease of multiple myeloma., PMID:30782613
IL-34-Dependent Intrarenal and Systemic Mechanisms Promote Lupus Nephritis in MRL-Faslpr Mice., PMID:30622154
Interleukin 34 (IL-34) cell-surface localization regulated by the molecular chaperone 78-kDa glucose-regulated protein facilitates the differentiation of monocytic cells., PMID:30573681
Interleukin 30 to Interleukin 40., PMID:30328794
Histone deacetylase 6 regulated expression of IL-8 is involved in the doxorubicin (Dox) resistance of osteosarcoma cells via modulating ABCB1 transcription., PMID:30273544
Neuron-related blood inflammatory markers as an objective evaluation tool for major depressive disorder: An exploratory pilot case-control study., PMID:30059939
Interleukin-34 Aggravates the Severity of Arthritis in Collagen-Induced Arthritis Mice by Inducing Interleukin-17 Production., PMID:29664689
Enhanced IL-34 expression in Nivolumab-resistant metastatic melanoma., PMID:29515691
Elevated Serum Interleukin-34 Level in Patients with Systemic Lupus Erythematosus Is Associated with Disease Activity., PMID:29472590
For research use only. Not for human or drug use.
