Catalog No.
FHB95610
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
Interleukin-1 beta, IL1B, Catabolin, IL1F2, IL-1 beta,IL-1β
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P01584
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0368
Adipose-Derived Mesenchymal Stromal/Stem Cells Reduce Inflammatory Responses and Partially Alleviate Skin Symptoms in Imiquimod-Induced Psoriasis-Like Dermatitis Model Mice., PMID:40500215
Sulfasalazine combined with anti-IL-1β mAb induces ferroptosis and immune modulation in oral squamous cell carcinoma., PMID:40425823
Systemic secukinumab treatment in patients with ankylosing spondylitis: the relationship between systemic and tear proinflammatory cytokines and ocular surface findings-a pilot study., PMID:40394377
Secretory IgA binding to FCRL3 triggers shared inflammatory cytokine secretion by human regulatory T cells and effector T cells., PMID:40313182
IL1B gene polymorphisms (rs1143627, rs16944) increase the risk of ANCA-associated vasculitis., PMID:40253228
Pulmonary Myeloid Cells in Mild Cases of COVID-19 Upregulate the Intracellular Fc Receptor TRIM21 and Transcribe Proteasome-Associated Molecules., PMID:40141410
Differential Roles of Macrophages and Microglia in Subretinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration., PMID:40111356
Tick salivary proteins metalloprotease and allergen-like p23 are associated with response to glycan α-Gal and mycobacterium infection., PMID:40087469
The effect of IL-1β inhibitor canakinumab (Ilaris®) on IL-6 production in human skeletal muscle cells., PMID:40048444
The prevalence of primary chronic rhinosinusitis in young adults from a Swedish birth cohort., PMID:40042341
Discovery and Phase 1 study of a novel monoclonal antibody against human IL-1β for the treatment of IL-1β-mediated diseases., PMID:39964852
Clinical Trial to Assess the Safety and Tolerability of Anti-IL 23 Monoclonal Antibody Guselkumab in Patients With Alcohol-Associated Liver Disease., PMID:39949265
Targeting the SARS-CoV-2 reservoir in long COVID., PMID:39947217
Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anti-citrullinated peptide antibody-positive early rheumatoid arthritis., PMID:39877346
THG-1/TSC22D4 Promotes IL-1 Signaling through Stabilization of TRAF6 in Squamous Cell Carcinoma., PMID:39869046
HERV-W Env Induces Neuron Pyroptosis via the NLRP3-CASP1-GSDMD Pathway in Recent-Onset Schizophrenia., PMID:39859234
Phase I study of BMS-986299, an NLRP3 agonist, as monotherapy and in combination with nivolumab and ipilimumab in patients with advanced solid tumors., PMID:39824531
Interleukin-1β Drives Disease Progression in Arrhythmogenic Cardiomyopathy., PMID:39763850
Platelet-neutrophil aggregate formation induces NLRP3 inflammasome activation in vaccine-induced thrombotic thrombocytopenia., PMID:39706368
Anti-Atopic Dermatitis Effect of Azalomycin F on 2,4-Dinitrofluorobenzene-Induced Mice and Potential Mechanism., PMID:39684557
Single-cell RNA sequencing reveals transcriptional changes in circulating immune cells from patients with severe asthma induced by biologics., PMID:39672815
Neisseria gonorrhoeae induces local secretion of IL-10 at the human cervix to promote colonization., PMID:39585777
Corticosteroid effects on IL-10 and IL-1β in U937-derived macrophages: A model for Kawasaki disease-associated inflammation., PMID:39577337
Suppression of renal crystal formation, inflammation, and fibrosis by blocking oncostatin M receptor β signaling., PMID:39572752
The IL-1β inhibitor canakinumab in previously treated lower-risk myelodysplastic syndromes: a phase 2 clinical trial., PMID:39537648
Small molecule inhibitors of IL-1R1/IL-1β interaction identified via transfer machine learning QSAR modelling., PMID:39515709
A human tissue-based model of renal inflammation., PMID:39476943
Chromatin remodelling drives immune cell-fibroblast communication in heart failure., PMID:39443808
Targeting immune-fibroblast cell communication in heart failure., PMID:39443792
Hypericum perforatum L. (St. John's Wort) in broilers diet improve growth performance, intestinal microflora and immunity., PMID:39427421
In vitro analysis of VEGF-mediated endothelial permeability and the potential therapeutic role of Anti-VEGF in severe dengue., PMID:39263317
Up-regulation of IL-1β and sPLA2-III in the medial prefrontal cortex contributes to orofacial and somatic hyperalgesia induced by malocclusion via glial-neuron crosstalk., PMID:39182540
Granulocyte colony-stimulating factor mediates bone loss via the activation of IL-1β/JNK signaling pathway in murine Staphylococcus aureus-induced osteomyelitis., PMID:39163688
Elucidating allergic reaction mechanisms in response to SARS-CoV-2 mRNA vaccination in adults., PMID:39033312
Mechanisms of programmed cell death associated to severe dengue in human renal lesions., PMID:39025381
LincR-PPP2R5C regulates IL-1β ubiquitination in macrophages and promotes airway inflammation and emphysema in a murine model of COPD., PMID:39018689
Blockade of IL1β and PD1 with Combination Chemotherapy Reduces Systemic Myeloid Suppression in Metastatic Pancreatic Cancer with Heterogeneous Effects in the Tumor., PMID:38990554
IL-1β Induces LDL Transcytosis by a Novel Pathway Involving LDLR and Rab27a., PMID:38989581
An antibody to IL-1 receptor 7 protects mice from LPS-induced tissue and systemic inflammation., PMID:38983847
Innate and adaptive immune response of Rainbow trout (Oncorhynchus mykiss) naturally infected with Yersinia ruckeri., PMID:38960109
Targeting IL-1 controls refractory pityriasis rubra pilaris., PMID:38959302
Single cell analyses reveal the PD-1 blockade response-related immune features in hepatocellular carcinoma., PMID:38948071
Intense impact of IL-1β expressing inflammatory macrophages in acute aortic dissection., PMID:38937528
Evaluating Single-Nucleotide Polymorphisms in Inflammasome Proteins and Serum Levels of IL-18 and IL-1β in Kidney Interstitial Damage in Anti-Neutrophilic Cytoplasmic Antibody-Associated Vasculitis., PMID:38928186
Extracellular NCOA4 is a mediator of septic death by activating the AGER-NFKB pathway., PMID:38916095
Obesity Enhances Non-Th2 Airway Inflammation in a Murine Model of Allergic Asthma., PMID:38892358
Macrophage IL-1β mediates atrial fibrillation risk in diabetic mice., PMID:38889387
Fcα Receptor Type I and Its Association with Atherosclerosis Development., PMID:38855431
Transcriptomic signatures of classical monocytes reveal pro-inflammatory modules and heterogeneity in polyarticular juvenile idiopathic arthritis., PMID:38835762
Characterization of Potential Target Genes of Borneol in Increasing Trastuzumab Sensitivity in HER2+ Trastuzumab-Resistant Breast Cancer: Bioinformatics and In Vitro Studies., PMID:38809634
For research use only. Not for human or drug use.
