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Anti-Z-DNA/Z-RNA Antibody (Z22)

Catalog #:   RGK24302 Specific References (0) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: DB, ELISA, EMSA, FCM, FuncS, IF, IHC, SPR
Overview

Catalog No.

RGK24302

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Applications

DB, ELISA, EMSA, FCM, FuncS, IF, IHC, SPR

Target

DNA, Z-DNA, ZDNA, Z DNA, Z RNA, ZRNA, Z RNA, Z NA, Z-NA, ZNA

Specificity

Z22 binds both Z-DNA, but not B-DNA or ssDNA (single-stranded DNA).

Concentration

1.76 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.02% Tween 20

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

Z22

Note

For research use only.

Data Image
  • SDS-PAGE
    SDS PAGE for Z-DNA/Z-RNA Antibody (Z22)
  • Immunofluorescence
    Figure 6. Lig3 PARylation establishes localized acidic environments promoting ecDNA biogenesis, with Z-DNA formation emerging as a potential echanism (H) Confocal images of Lig3-mtagBFP, MYC ecDNA junction with Z22 IF, and the statistics of fluorescence intensity for each channel (right). Scale bars: 5 μm, 0.5 μm for zoom views. (I) qPCR of ecDNA breakpoint and segments in the 5′ and 3′ end-joining region. *p < 0.05, **p < 0.01, ***p < 0.001.
    Data sourced from citation (PMID: 40769147)
References
Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-Z-DNA/Z-RNA Antibody (Z22) [RGK24302]
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