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Anti-Human CDH17 Antibody (SAA0347)

Catalog #:   FHG31410 Specific References (47) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: ELISA, FCM, IHC, SPR, WB
Accession: Q12864
Overview

Catalog No.

FHG31410

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

Cadherin-17, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin, LI-cadherin, CDH17

Concentration

1.85 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q12864

Applications

ELISA, FCM, IHC, SPR, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0347

Data Image
References

Nanobody Engineered and Photosensitiser Loaded Bacterial Outer Membrane Vesicles Potentiate Antitumour Immunity and Immunotherapy., PMID:40240911

Development and Characterization of the [177Lu]Lu-Labeled Anti-CDH17 Nanobody Derivative for Radioimmunotherapy in the Gastric Cancer Xenograft Model., PMID:40088168

A bispecific antibody-drug conjugate targeting pCAD and CDH17 has antitumor activity and improved tumor-specificity., PMID:39762718

Variability in morphology and immunohistochemistry of Crohn's disease-associated small bowel neoplasms: implications of Claudin 18 and Cadherin 17 expression for tumor-targeted immunotherapies., PMID:39164422

Nanobody-Engineered Biohybrid Bacteria Targeting Gastrointestinal Cancers Induce Robust STING-Mediated Anti-Tumor Immunity., PMID:38888519

Cadherin-17 as a target for the immunoPET of adenocarcinoma., PMID:38625402

Cadherin-17 (CDH17) expression in human cancer: A tissue microarray study on 18,131 tumors., PMID:38452580

The diagnostic significance of CDH17-positive circulating tumor cells in patients with colorectal cancer., PMID:36744385

CDH17 nanobodies facilitate rapid imaging of gastric cancer and efficient delivery of immunotoxin., PMID:36435809

A proximity labeling method for protein-protein interactions on cell membrane., PMID:35685794

Aberrant expression of SATB2, CDX2, CDH17 and CK20 in hepatocellular carcinoma: a pathological, clinical and outcome study., PMID:34036629

CDH6-activated αIIbβ3 crosstalks with α2β1 to trigger cellular adhesion and invasion in metastatic ovarian and renal cancers., PMID:33715292

Selective Tumor Cell Apoptosis and Tumor Regression in CDH17-Positive Colorectal Cancer Models using BI 905711, a Novel Liver-Sparing TRAILR2 Agonist., PMID:33037135

Cadherin-17 Targeted Near-Infrared Photoimmunotherapy for Treatment of Gastrointestinal Cancer., PMID:32931292

The Diagnostic Value of Cadherin 17 and CDX2 Expression as Immunohistochemical Markers in Colorectal Adenocarcinoma., PMID:32929682

Quantifying drug tissue biodistribution by integrating high content screening with deep-learning analysis., PMID:32873881

64Cu-labeled minibody D2101 visualizes CDH17-positive gastric cancer xenografts with short waiting time., PMID:32371673

111In-labeled anti-cadherin17 antibody D2101 has potential as a noninvasive imaging probe for diagnosing gastric cancer and lymph-node metastasis., PMID:31605356

Beyond N-Cadherin, Relevance of Cadherins 5, 6 and 17 in Cancer Progression and Metastasis., PMID:31324051

Simultaneous amperometric immunosensing of the metastasis-related biomarkers IL-13Rα2 and CDH-17 by using grafted screen-printed electrodes and a composite prepared from quantum dots and carbon nanotubes for signal amplification., PMID:31183566

Determination of Cadherin-17 in Tumor Tissues of Different Metastatic Grade Using a Single Incubation-Step Amperometric Immunosensor., PMID:30134108

RGD cadherins and α2β1 integrin in cancer metastasis: A dangerous liaison., PMID:29673969

Synergistic Cytotoxic Effect on Gastric Cancer Cells of an Immunotoxin Cocktail in Which Antibodies Recognize Different Epitopes on CDH17., PMID:29474162

Targeting CDH17 in Cancer: When Blocking the Ligand Beats Blocking the Receptor?, PMID:29084915

Monoclonal Antibodies Directed against Cadherin RGD Exhibit Therapeutic Activity against Melanoma and Colorectal Cancer Metastasis., PMID:28916526

CDH17 Is a More Sensitive Marker for Gastric Adenocarcinoma Than CK20 and CDX2., PMID:28029907

Identification and Validation of Novel Subtype-Specific Protein Biomarkers in Pancreatic Ductal Adenocarcinoma., PMID:27846146

Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer., PMID:27771609

BILL-cadherin/cadherin-17 contributes to the survival of memory B cells., PMID:25612318

Targeting cadherin-17 inactivates Ras/Raf/MEK/ERK signaling and inhibits cell proliferation in gastric cancer., PMID:24465527

Anti-cadherin-17 antibody modulates beta-catenin signaling and tumorigenicity of hepatocellular carcinoma., PMID:24039755

Liver-intestine-cadherin is a sensitive marker of intestinal differentiation during Barrett's carcinogenesis., PMID:23053896

The predictive effect of cadherin-17 on lymph node micrometastasis in pN0 gastric cancer., PMID:22009269

Blockade of proliferation and migration of gastric cancer via targeting CDH17 with an artificial microRNA., PMID:20393816

[Effect of monoclonal antibodies against LI-cadherin on the proliferation of human hepatocellular carcinoma cells]., PMID:19460698

Phenotypic classification of gastric signet ring cell carcinoma and its relationship with clinicopathologic parameters and prognosis., PMID:17589897

Only VpreB1, but not VpreB2, is expressed at levels which allow normal development of B cells., PMID:16361315

Lymphocyte-expressed BILL-cadherin/cadherin-17 contributes to the development of B cells at two stages., PMID:15688343

Reduced expression of liver-intestine cadherin is associated with progression and lymph node metastasis of human colorectal carcinoma., PMID:15279905

Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin., PMID:15023525

Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas., PMID:12824888

LI-cadherin: a marker of gastric metaplasia and neoplasia., PMID:11413113

LI-cadherin gene expression during mouse intestinal development., PMID:11376485

The identification of a nonclassical cadherin expressed during B cell development and its interaction with surrogate light chain., PMID:10906147

Overexpression of human intestinal oligopeptide transporter in mammalian cells via adenoviral transduction., PMID:9755888

Cloning and characterization of a rat H+/peptide cotransporter mediating absorption of beta-lactam antibiotics in the intestine and kidney., PMID:8531138

Association of intestinal peptide transport with a protein related to the cadherin superfamily., PMID:8153632

Datasheet
$ 225
Product specifications
50 μg 225 100 μg 372

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For research use only. Not for human or drug use.

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Anti-Human CDH17 Antibody (SAA0347) [FHG31410]
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