Research Grade Forimtamig

Catalog No.

DHK07702

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1-lambda/kappa

Clonality

Monoclonal

Target

GPRC5D, G-protein coupled receptor family C group 5 member D, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain

Concentration

1.8 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NZD1 & P07766

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

rg6234, CAS: 2649379-96-2

Clone ID

Forimtamig

T cell margination: investigating the detour of T cells following forimtamig treatment in humanized mice., PMID:39686589

Comprehensive Review of Bispecific Antibody Constructs In Multiple Myeloma: Affinities, Dosing Strategies and Future Perspectives., PMID:39676006

Forimtamig, a novel GPRC5D-targeting T-cell bispecific antibody with a 2+1 format, for the treatment of multiple myeloma., PMID:39476124

GPRC5D as a novel target for the treatment of multiple myeloma: a narrative review., PMID:38307865

T-cell redirecting bispecific and trispecific antibodies in multiple myeloma beyond BCMA., PMID:37501530

Bispecific Monoclonal Antibodies in Multiple Myeloma: Data from ASH 2022: A Podcast., PMID:37328635

Document Download

Research Grade Forimtamig.pdf