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Research Grade Adalimumab

Catalog #:   DHB94402 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHB94402

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1

Concentration

1.9 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01375

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

ABP 501, D2E7, Adalimumab, Adalimumab Beta, CAS: 331731-18-1

Clone ID

Adalimumab Beta

Data Image
  • Bioactivity
    Detects Human TNFa/TNF-alpha in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Adalimumab Beta
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Long-Term Effectiveness and Safety of Weekly Adalimumab in Refractory Non-Infectious Uveitis., PMID:40511491

A physiologically based pharmacokinetic model to describe [89Zr]Zr-DFO-Adalimumab specific activity after intravitreal administration to rats with endotoxin-induced uveitis., PMID:40505897

Development and validation of a novel Endoscopic ulcer Activity Score for Evaluation of Crohn's Disease (EASE-CD) using data from two randomised controlled trials., PMID:40505666

Summary of Research: Immunogenicity of Adalimumab Reference Product and Adalimumab-adbm in Patients with Rheumatoid Arthritis, Crohn's Disease, and Chronic Plaque Psoriasis: A Pooled Analysis of the VOLTAIRE trials., PMID:40498294

Upadacitinib for ulcerative colitis and pyoderma gangrenosum in a patient with schizophrenia on long-term risperidone: A case report., PMID:40495949

Efficacy and Safety of ABBV-154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo-Controlled Trial., PMID:40495262

Deep learning-based ranking method for subgroup and predictive biomarker identification in patients., PMID:40494908

A single-cell RNA-seq dataset of synovial fluid from rheumatoid arthritis treated with TNF-α/JAK inhibitor., PMID:40494845

Comparison and analysis of biological drug consumption in two Italian hospital settings: Governance actions and prescribing appropriateness., PMID:40494065

Multiple Switches Between Adalimumab-fkjp and Reference Adalimumab in Moderate-to-Severe Chronic Plaque Psoriasis: A Multicenter, Double-Blind, Parallel Group, Randomized Clinical Trial for Interchangeability., PMID:40493334

Management of Pediatric Acne Vulgaris and Hidradenitis Suppurativa in Minoritized and Underserved Populations., PMID:40489363

Metabolism and Response to Stress Gene Signatures Reveal Ulcerative Colitis Heterogeneity and Identify Patients With Increased Response to Therapy., PMID:40488582

Treatment of refractory pityriasis rubra pilaris with biologic therapy: a case series., PMID:40488550

Reply to Correspondence to Recurrence Risk in Pediatric Non-Infectious Uveitis during Adalimumab Tapering., PMID:40485634

Drug survival, long-term safety and efficacy of anti-TNF-alpha biosimilars: a monocentric retrospective study., PMID:40485573

Treatment sequences, outcomes, healthcare utilization, and costs in patients with inflammatory bowel diseases requiring advanced treatment-real world comparative effectiveness from German claims data., PMID:40481399

Tumor necrosis factor α inhibitor-induced alopecia in pediatric patients: a cohort of 20 patients and review of the literature., PMID:40481366

A Survey of Diagnostic and Management Practices in Retinal Vasculitis: International Uveitis Study Group (IUSG) Retinal Vasculitis Study (ReViSe)-Report 5., PMID:40478525

Effects of Adalimumab on Mitochondria of Psoriatic Mesenchymal Stem Cells., PMID:40478194

Case Report: Kyrieleis plaques in an unusual Behcet's disease uveitis., PMID:40475959

Case Report: Effectiveness of deucravacitinib in chronic recurrent multifocal osteomyelitis and concomitant psoriasis., PMID:40475785

Pharmacotherapy for non-infectious uveitis: spotlight on phase III clinical trials of locally injected or implanted therapeutics and systemic immunomodulatory drugs., PMID:40473986

Anti-tumor Necrosis Factor-Alpha (TNF-α)-Induced Hypertrophic Lichen Planus: A Case Report., PMID:40470457

Pharmacogenomics of TNF inhibitors., PMID:40469293

Lupus panniculitis secondary to treatment with adalimumab in a patient with rheumatoid arthritis., PMID:40466251

Adalimumab Monotherapy vs Adalimumab With Methotrexate for Psoriasis., PMID:40465280

High-Throughput Human Gut Immune Co-Culture Model for Evaluating Inflammatory Bowel Disease Anti-Inflammatory Therapies., PMID:40462955

Benefit-risk analysis of upadacitinib versus adalimumab in patients with rheumatoid arthritis and higher or lower risk of cardiovascular disease., PMID:40461266

Severe paradoxical generalized pustular psoriasis induced by adalimumab biosimilar successfully treated with brodalumab., PMID:40457932

Correspondence to Recurrence Risk in Pediatric Non-Infectious Uveitis during Adalimumab Tapering: An International Multicenter Retrospective Study., PMID:40456698

Treatment of Autoimmune Enteropathy With Vedolizumab., PMID:40452653

Immunoglobulin A vasculitis and pustular psoriasis precipitated by Tawon Liar: a case report., PMID:40448236

Letter to the Editor: Assessing early therapeutic drug monitoring of adalimumab as a predictor of treatment efficacy and immunogenicity in rheumatic diseases: "early therapeutic drug monitoring of adalimumab"., PMID:40445523

Clinical Response to Adalimumab Therapy and Its Determinants in Patients With Radiographic Axial Spondyloarthritis: A Prospective Real-World Study in Taiwan., PMID:40443026

Cross-phenotype genome-wide association study supports shared genetic etiology between skin and gastrointestinal tract diseases., PMID:40441863

Physician Burden and Time Delays in Initiating Immunomodulatory Therapy for Non-infectious Uveitis and Inflammatory Eye Diseases., PMID:40441503

Systematic review of comparative studies on emerging psoriasis treatments: comparing biologics with biologics, small molecule inhibitors with small molecule inhibitors, and biologics with small molecule inhibitors., PMID:40439875

Drug survival of IL-23 and IL-17 inhibitors versus other biologics for psoriasis: A British Association of Dermatologists Biologics and Immunomodulators Register cohort study., PMID:40439435

Uveitis in Adults: A Review., PMID:40434762

Failure of primary immunosuppressive agents in uveitis., PMID:40434459

JAK-STAT inhibitors in noninfectious uveitis - A review., PMID:40434456

Optimizing Biologic Therapy for the Prevention of Post-Operative Recurrence in Crohn's Disease: Current Evidence and Future Perspectives., PMID:40427059

Subconjunctival Adalimumab for Noninfectious Uveitis: A Prospective Pilot Study., PMID:40423087

Anti-Adalimumab Antibodies Purified from Juvenile Idiopathic Arthritis Patients: Kinetic Characterization Among Biosimilars., PMID:40422017

Efficacy and safety of dual-targeted therapy for refractory inflammatory bowel disease: a retrospective case series from three tertiary general hospitals in China., PMID:40421289

Predictors of drug survival of biologics in hidradenitis suppurativa: A systematic review and meta-analysis., PMID:40419221

Comparative efficacy, safety and immunogenicity of biosimilars and their reference biologic drugs in ankylosing spondylitis: a systematic review and meta-analysis of randomized controlled trials., PMID:40418343

The position of anti-Tumor Necrosis Factor agents for the treatment of adult patients with Crohn's disease., PMID:40418234

The Relationship Between TNF-α Inhibitor Potency and HBV Reactivation in Patients With Rheumatic Disorders., PMID:40418092

Lingual Dystonia Following Thalamic Infarction in a Patient on Methotrexate Therapy for Hidradenitis Suppurativa., PMID:40416235

Datasheet

Document Download

Research Grade Adalimumab.pdf

 

$ 372
Product specifications
100 μg 372 1 mg 1486

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Research Grade Adalimumab [DHB94402]
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