Catalog No.
EHJ75001
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Gln178
Predicted molecular weight
45.84 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UGN4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Inhibitory receptor protein 60, IRp60, CMRF35-H, CLM-8, CMRF35-H9, CMRF35-like molecule 8, CD300A, NK inhibitory receptor, IgSF12, CD300a, CMRF35H, IRC1/IRC2, IGSF12, CD300 antigen-like family member A, CMRF-35-H9, Immunoglobulin superfamily member 12
A Humanized Monoclonal Antibody Against CD300A Ameliorates Acute Ischemic Stroke in Humanized Mice., PMID:39804190
Multi-modal analysis reveals tumor and immune features distinguishing EBV-positive and EBV-negative post-transplant lymphoproliferative disorders., PMID:39657667
Pro-resolving lipid mediators and therapeutic innovations in resolution of inflammation., PMID:39566561
Universal protection of allogeneic T-cell therapies from natural killer cells via CD300a agonism., PMID:39368806
A squalene oil emulsified MPL-A and anti-CD200/CD300a antibodies adjuvanted whole-killed Leishmania vaccine provides durable immunity against L. donovani parasites., PMID:39288578
Virus-driven dysregulation of the BCR pathway: a potential mechanism for the high prevalence of HIV related B-cell lymphoma., PMID:39196379
The Role of TIM-1 and CD300a in Zika Virus Infection Investigated with Cell-Based Electrical Impedance., PMID:39194591
The effects of air and transportation noise pollution-related altered blood gene expression, DNA methylation, and protein abundance levels on gastrointestinal diseases risk., PMID:39163931
Pathogen stimulations and immune cells synergistically affect the gene expression profile characteristics of porcine peripheral blood mononuclear cells., PMID:39054472
Untargeted blood serum proteomics identifies novel proteins related to neurological recovery after human spinal cord injury., PMID:39020346
Blockade of CD300A enhances the ability of human NK cells to lyse hematologic malignancies., PMID:38425216
GW0742 reduces mast cells degranulation and attenuates neurological impairments via PPARβ/δ/CD300a/SHP1 pathway after GMH in neonatal rats., PMID:37995951
Development of Monoclonal Antibodies Specific to Either CD300AR111 or CD300AQ111 or Both., PMID:37902989
Adjuvantation of whole-killed Leishmania vaccine with anti-CD200 and anti-CD300a antibodies potentiates its efficacy and provides protection against wild-type parasites., PMID:37778149
Human IgMhiCD300a+ B Cells Are Circulating Marginal Zone Memory B Cells That Respond to Pneumococcal Polysaccharides and Their Frequency Is Decreased in People Living with HIV., PMID:37762055
A Pilot Urinary Proteome Study Reveals Widespread Influences of Circadian Rhythm Disruption by Sleep Deprivation., PMID:37458940
Immunophenotypic and Functional Characterization of Eosinophil and Migratory Dendritic Cell Subsets during Filarial Manifestation of Tropical Pulmonary Eosinophilia., PMID:37040430
CD300a Regulates Mouse Macrophage Functionality in Allergic Inflammation., PMID:36928079
High Expression of CD300A Predicts Poor Survival in Acute Myeloid Leukemia., PMID:36746134
CD25 as a unique marker on human basophils in stable-mildly symptomatic allergic asthma., PMID:36685514
Leishmania donovani induces CD300a expression to dampen effector properties of CD11c+ dendritic and antigen activated CD8+ T cells., PMID:36610528
Identifying transcript-level differential expression in primary human immune cells., PMID:36527757
Novel peanut-specific human IgE monoclonal antibodies enable screens for inhibitors of the effector phase in food allergy., PMID:36248809
Pan-cancer analysis identifies CD300 molecules as potential immune regulators and promising therapeutic targets in acute myeloid leukemia., PMID:35642341
Increased expression of TIGIT and KLRG1 correlates with impaired CD56bright NK cell immunity in HPV16-related cervical intraepithelial neoplasia., PMID:35413989
Overexpression of FcεRI on Bone Marrow Mast Cells, but Not MRGPRX2, in Clonal Mast Cell Disorders With Wasp Venom Anaphylaxis., PMID:35281031
Cromolyn Sodium differentially regulates human mast cell and mouse leukocyte responses to control allergic inflammation., PMID:35278626
Identification of differentially expressed genes associated with coronary in-stent restenosis by integrated bioinformatics approaches., PMID:35144391
CD300a Receptor Blocking Enhances Early Clearance of Leishmania donovani From Its Mammalian Host Through Modulation of Effector Functions of Phagocytic and Antigen Experienced T Cells., PMID:35116028
Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a., PMID:34751648
CD300a blockade enhances efferocytosis by infiltrating myeloid cells and ameliorates neuronal deficit after ischemic stroke., PMID:34652960
AVEXIS technology identifies novel platelet-leukocyte binding partners including CD148-CD300a., PMID:34555847
Endometrial Expression of Cell Adhesion Genes in Recurrent Implantation Failure Patients in Ongoing IVF Cycle., PMID:34410653
The inhibitory receptor CD300a is essential for neutrophil-mediated clearance of urinary tract infection in mice., PMID:34268737
Development of a blocker of the universal phosphatidylserine- and phosphatidylethanolamine-dependent viral entry pathways., PMID:34020328
CD300a contributes to the resolution of articular inflammation triggered by MSU crystals by controlling neutrophil apoptosis., PMID:34002852
Impact of Cytomegalovirus and Age on T-Cell Subsets Defined by CD161, CD300a, and/or CD57 Expression in Healthy Andalusians., PMID:33993242
Dexamethasone and CD300a activation display additive inhibitory effect on human and murine mast cell functions., PMID:33797117
T Cell Activation, Highly Armed Cytotoxic Cells and a Shift in Monocytes CD300 Receptors Expression Is Characteristic of Patients With Severe COVID-19., PMID:33777054
Peripheral blood cultured mast cells: Phenotypic and functional outcomes of different culture protocols., PMID:33647250
Direct Infection of B Cells by Dengue Virus Modulates B Cell Responses in a Cambodian Pediatric Cohort., PMID:33643283
CD300a and CD300f molecules regulate the function of leukocytes., PMID:33548578
Unique cellular interaction of macrophage-targeted liposomes potentiates anti-inflammatory activity., PMID:32558834
Potential genes and pathways along with immune cells infiltration in the progression of atherosclerosis identified via microarray gene expression dataset re-analysis., PMID:32379583
CD300a identifies a CD4+ memory T cell subset with a higher susceptibility to HIV-1 infection., PMID:32287074
Polyfunctional HIV-1 specific response by CD8+ T lymphocytes expressing high levels of CD300a., PMID:32269232
The role of phosphatidylserine recognition receptors in multiple biological functions., PMID:32226456
CD300a inhibits CD16-mediated NK cell effector functions in HIV-1-infected patients., PMID:31467415
Autonomous regulation of IgE-mediated mast cell degranulation and immediate hypersensitivity reaction by an inhibitory receptor CD300a., PMID:31155312
The immunoreceptor CD300a controls the intensity of inflammation and dysfunction in a model of Ag-induced arthritis in mice., PMID:31107994
For research use only. Not for human or drug use.
