Catalog No.
                        PVV13501
                        
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Species reactivity
                        
                        Monkeypox virus (strain Zaire-96-I-16) (MPX)                        
                                                
                                            Host species
                        
                        Rabbit                        
                                                
                                            Isotype
                        
                        IgG                        
                                                
                                            Clonality
                        
                        Polyclonal                        
                                                
                                            Immunogen
                        
                        E. coli - derived recombinant Monkeypox virus/MPXV B6R/SL-159 (Thr20-His279).                        
                                                
                                            
                                            Tested applications
                        
                        ELISA: 1:4000-1:8000, IHC: 1:50-1:200, WB: 1:1000-1:4000                        
                                                
                                            Target
                        
                        B6R/SL-159                        
                                                
                                            
                                            Concentration
                        
                        4.37 mg/ml                        
                                                
                                            
                                            
                                            Purification
                        
                        Purified by antigen affinity column.                        
                                                
                                            
                                            
                                            Applications
                        
                        ELISA, IHC, WB                        
                                                
                                            Form
                        
                        Liquid                        
                                                
                                            Storage buffer
                        
                        0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Stability and Storage
                        
                        Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                        
                 
                
                
                                            Polyvalent mpox mRNA vaccines elicit robust immune responses and confer potent protection against vaccinia virus. [PVV13501]
                                            Circular RNA vaccines against monkeypox virus provide potent protection against vaccinia virus infection in mice
                                            Multi-Component Protein Vaccine Induces a Strong and Long-Term Immune Response Against Monkeypox Virus. [PVV13501]
                                            An Mpox Multi-Antigen-Tandem Bivalent mRNA Candidate Vaccine Effectively Protects Mice Against the Vaccinia Virus. [PVV13501]
                                            The conserved poxvirus membrane entry-fusion apparatus component OPG147 targets MITA/STING for immune evasion. [PVV13501]
                                            Generation and characterization of neutralizing antibodies against M1R and B6R proteins of monkeypox virus., PMID:40164599
                                            Rational mpox vaccine design: immunogenicity and protective effect of individual and multicomponent proteins in mice., PMID:40105863
                                            Immunogenicity of monkeypox virus surface proteins and cross-reactive antibody responses in vaccinated and infected individuals: implications for vaccine and therapeutic development., PMID:39994775
                                            Development and validation of a quantitative Orthopoxvirus immunoassay to evaluate and differentiate serological responses to Mpox infection and vaccination., PMID:39987746
                                            Long-Lasting Protection and Dose Optimization of MPXV Polyvalent Mpox mRNA Vaccines Against Lethal Vaccinia Virus Challenge in Mice., PMID:39726255
                                            A penta-component mpox mRNA vaccine induces protective immunity in nonhuman primates., PMID:39639037
                                            Single-chain A35R-M1R-B6R trivalent mRNA vaccines protect mice against both mpox virus and vaccinia virus., PMID:39423738
                                            Mpox global health emergency: Insights into the virus, immune responses, and advancements in vaccines PART II: Insights into the advancements in vaccines., PMID:39417768
                                            Systematic evaluation of the induction of efficient neutralizing antibodies by recombinant multicomponent subunit vaccines against monkeypox virus., PMID:39321566
                                            Identification of mpox M1R and B6R monoclonal and bispecific antibodies that efficiently neutralize authentic mpox virus., PMID:39233480
                                            Analysis of binding and authentic virus-neutralizing activities of immune sera induced by various monkeypox virus antigens., PMID:38829493
                                            Polyvalent mpox mRNA vaccines elicit robust immune responses and confer potent protection against vaccinia virus., PMID:38787725
                                            Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques., PMID:38536937
                                            Evaluation and comparison of immune responses induced by two Mpox mRNA vaccine candidates in mice., PMID:37800627
                                            Cross-reactive antibody response to Monkeypox virus surface proteins in a small proportion of individuals with and without Chinese smallpox vaccination history., PMID:37784185
                                            Duration of humoral immunity from smallpox vaccination and its cross-reaction with Mpox virus., PMID:37709783
                                            Examination of the cross-reactivity between vaccinia virus Tiantan strain and monkeypox virus., PMID:37473582
                                            Recombinant proteins A29L, M1R, A35R, and B6R vaccination protects mice from mpox virus challenge., PMID:37435062
                                            Mpox virus mRNA-lipid nanoparticle vaccine candidates evoke antibody responses and drive protection against the Vaccinia virus challenge in mice., PMID:37429529
                                            Multi-valent mRNA vaccines against monkeypox enveloped or mature viron surface antigens demonstrate robust immune response and neutralizing activity., PMID:37300753
                                            Monkeypox virus quadrivalent mRNA vaccine induces immune response and protects against vaccinia virus., PMID:37117161
                                            Rational development of multicomponent mRNA vaccine candidates against mpox., PMID:36947428
                                            Circular RNA vaccines against monkeypox virus provide potent protection against vaccinia virus infection in mice. [PVV13501]