Catalog No.
RHC59302
Species reactivity
Human, Mouse, Rat, Rabbit
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
UBC, Polyubiquitin-C, Ubiquitin
Concentration
1.65 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P0CG48
Applications
ELISA, IP, WB
Form
Liquid
Storage buffer
0.94mM Citric acid monohydrate, 16.7mM Trisodium citrate dihydrate, 6.2% Sucrose, pH 6.5, 0.01% Tween 80.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0329
Inactivation of SIAH-1 E3 ligase attenuates Aβ toxicity by suppressing ubiquitin-dependent DVE-1 degradation in Caenorhabditis elegans models of Alzheimer's disease., PMID:40349774
Structural visualization of HECT-type E3 ligase Ufd4 accepting and transferring ubiquitin to form K29/K48-branched polyubiquitination., PMID:40341121
Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs., PMID:40101708
Glia maturation factor-γ regulates amyloid-β42 phagocytosis through scavenger receptor class A type I in murine macrophages., PMID:39243388
Global ubiquitinome analysis reveals the role of E3 ubiquitin ligase FaBRIZ in strawberry fruit ripening., PMID:36215033
Differential Degradation of TRA2A and PYCR2 Mediated by Ubiquitin E3 Ligase E4B., PMID:35669517
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies., PMID:34270554
ZNF213 negatively controls triple negative breast cancer progression via Hippo/YAP signaling., PMID:33939216
Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer., PMID:32521270
Identification of linear polyubiquitin chain immunoreactivity in tau pathology of Alzheimer's disease., PMID:30885635
Proteasome inhibition boosts autophagic degradation of ubiquitinated-AGR2 and enhances the antitumor efficiency of bevacizumab., PMID:30647455
Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling., PMID:28943312
TRIM26 negatively regulates interferon-β production and antiviral response through polyubiquitination and degradation of nuclear IRF3., PMID:25763818
Methods to assess the activation of the alternative (noncanonical) NF-κB pathway by non-death TNF receptors., PMID:25736746
NRAGE promotes cell proliferation by stabilizing PCNA in a ubiquitin-proteasome pathway in esophageal carcinomas., PMID:24710624
Using antiubiquitin antibodies to probe the ubiquitination state within rhTRIM5α cytoplasmic bodies., PMID:23799296
Polyubiquitination and proteasomal turnover controls the anti-apoptotic activity of Bcl-B., PMID:23563182
NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4., PMID:22388039
ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination., PMID:20406983
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies., PMID:18724939
For research use only. Not for human or drug use.
