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Anti-Human Gal-1/LGALS1 Antibody (8A12)

Catalog #:   RHC40101 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA, WB
Accession: P09382, P16045
Overview

Catalog No.

RHC40101

Species reactivity

Human, Mouse

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

HLBP14, Lactose-binding lectin 1, LGALS1, HBL, HPL, Beta-galactoside-binding lectin L-14-I, Gal-1, Lectin galactoside-binding soluble 1, Putative MAPK-activating protein PM12, S-Lac lectin 1, Galaptin, Galectin-1, 14 kDa laminin-binding protein, 14 kDa lectin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P09382, P16045

Applications

ELISA, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

8A12

Data Image
References

Impact of galectin-1's redox state on its lectin activity and monomer-dimer equilibrium. Focusing on oxidized Gal-1., PMID:39755294

Ganoderic acid T, a Ganoderma triterpenoid, modulates the tumor microenvironment and enhances the chemotherapy and immunotherapy efficacy through downregulating galectin-1 levels., PMID:39142358

Pre-B cell receptor acts as a selectivity switch for galectin-1 at the pre-B cell surface., PMID:39058594

Nematode Galectin Inhibits Basophilic Leukaemia RBL-2H3 Cells Apoptosis in IgE-Mediated Activation., PMID:39000527

Circulating immune-related proteins associated with immune checkpoint inhibitor efficacy in patients with pancreatic ductal adenocarcinoma., PMID:38838501

Noninvasively Deciphering the Immunosuppressive Tumor Microenvironment Using Galectin-1 PET to Inform Immunotherapy Responses., PMID:38514084

Identification of a capsular polysaccharide from Enterococcus faecium U0317 using a targeted approach to discover immunogenic carbohydrates for vaccine development., PMID:38368077

Enzymatically-derived oligo-carrageenans interact with α-Gal antibodies and Galectin-3., PMID:37985065

Guideline for allergological diagnosis of drug hypersensitivity reactions: S2k Guideline of the German Society for Allergology and Clinical Immunology (DGAKI) in cooperation with the German Dermatological Society (DDG), the Association of German Allergologists (ÄDA), the German Society for Pediatric Allergology (GPA), the German Contact Dermatitis Research Group (DKG), the German Society for Pneumology (DGP), the German Society of Otorhinolaryngology, Head and Neck Surgery, the Austrian Society of Allergology and Immunology (ÖGAI), the Austrian Society of Dermatology and Venereology (ÖGDV), the German Academy of Allergology and Environmental Medicine (DAAU), and the German Documentation Center for Severe Skin Reactions (dZh)., PMID:37705676

The role of basophil activation test and component-resolved diagnostics in the workup of egg allergy in children at low risk for severe allergic reactions: A real-life study., PMID:37622260

Galanin System in the Human Bile Duct and Perihilar Cholangiocarcinoma., PMID:37443714

Generation and characterization of a monoclonal antibody that binds to Galectin-1., PMID:37209931

Decoding Strategies to Evade Immunoregulators Galectin-1, -3, and -9 and Their Ligands as Novel Therapeutics in Cancer Immunotherapy., PMID:36555198

Plasma galectins and metabolites in advanced head and neck carcinomas: evidence of distinct immune characteristics linked to hypopharyngeal tumors., PMID:36545254

Molecular sensitization patterns of common food-and respiratory allergens in the Hungarian population., PMID:36400113

Regulatory T cells, damage-associated molecular patterns, and myeloid-derived suppressor cells in bronchoalveolar lavage fluid interlinked with chronic obstructive pulmonary disease severity: An observational study., PMID:35687771

Role of MDM2, CDK4, BCL2, Parafibromin and Galectin 1 in Differentiating Osteosarcoma from its Benign Fibro-osseous Lesions., PMID:35220546

Dual electrochemical sensing of spiked virus and SARS-CoV-2 using natural bed-receptor (MV-gal1)., PMID:34836981

Prevalence of serum galectin-1 autoantibodies in seven types of cancer: A potential biomarker., PMID:34276998

Serum galectin-9 could be a potential biomarker in assessing the disease activity of antineutrophil cytoplasmic antibody-associated vasculitis., PMID:34001301

A minigene DNA vaccine encoding peptide epitopes derived from Galectin-1 has protective antitumoral effects in a model of neuroblastoma., PMID:33848518

Minor N-Glycan Mapping of Monoclonal Antibody Therapeutics Using Middle-Down NMR Spectroscopy., PMID:33305950

Association of IgG Glycosylation and Esophageal Precancerosis Beyond Inflammation., PMID:33303693

Characterization of a neutralizing anti-human galectin-1 monoclonal antibody with angioregulatory and immunomodulatory activities., PMID:33006019

Label free Impedimetric Immunosensor for effective bladder Cancer detection in clinical urine samples., PMID:32607868

In contrast to melanocytes, keratinocytes of normal human adult interfollicular epidermis do not express galectin-1., PMID:32566954

Increased serum levels of galectin-9 in patients with chikungunya fever., PMID:32565125

Galectin-1 expression in oral squamous cell carcinoma: An immunohistochemical study., PMID:32508476

Galectin-1 and Galectin-3 Expression in Lesional Skin of Patients With Systemic Sclerosis-Association With Disease Severity., PMID:32501939

Galanin System in Human Glioma and Pituitary Adenoma., PMID:32265844

No Bull: A Case of Alpha-Gal Syndrome Associated With Buffalo Meat Sensitivity., PMID:31840005

A general protein O-glycosylation machinery conserved in Burkholderia species improves bacterial fitness and elicits glycan immunogenicity in humans., PMID:31350337

Convergent synthesis of tetra- and penta-saccharide fragments of dimeric Lewis X., PMID:31276881

Anti-inflammatory Property of Galectin-1 in a Murine Model of Allergic Airway Inflammation., PMID:31214624

Extract Methods, Molecular Characteristics, and Bioactivities of Polysaccharide from Alfalfa (Medicago sativa L.)., PMID:31137802

Validation of antibody-based tools for galanin research., PMID:30196126

The opposite roles of PAS-5 and Galectin-1 in immune response during the early infection of Angiostrongylus cantonensis., PMID:29843794

Immunoglobulins from sera of APS patients bind HTR-8/SVneo trophoblast cell line and reduce additional mediators of cell invasion., PMID:29102762

Toward a new and noninvasive diagnostic method of papillary thyroid cancer by using peptide vectorized contrast agents targeted to galectin-1., PMID:28986753

Anti-inflammatory effect of galectin-1 in a murine model of atopic dermatitis., PMID:28664215

Combined Anti-VEGF and Anti-CTLA-4 Therapy Elicits Humoral Immunity to Galectin-1 Which Is Associated with Favorable Clinical Outcomes., PMID:28473314

The Influence of Tetrodotoxin (TTX) on the Distribution and Chemical Coding of Caudal Mesenteric Ganglion (CaMG) Neurons Supplying the Porcine Urinary Bladder., PMID:28358321

Transgenic expression of human leukocyte antigen-E attenuates GalKO.hCD46 porcine lung xenograft injury., PMID:28258595

Galectin-1 expression is associated with tumour immunity and prognosis in gingival squamous cell carcinoma., PMID:28108653

Galectin-1 inhibits oral-intestinal allergy syndrome., PMID:28086216

Target-specific NMR detection of protein-ligand interactions with antibody-relayed 15N-group selective STD., PMID:27885546

The influence of resiniferatoxin on the chemical coding of caudal mesenteric ganglion neurons supplying the urinary bladder in the pig., PMID:27779483

Placental Expression Patterns of Galectin-1, Galectin-2, Galectin-3 and Galectin-13 in Cases of Intrauterine Growth Restriction (IUGR)., PMID:27070577

Immunological evaluation of the entirely carbohydrate-based Thomsen-Friedenreich - PS B conjugate., PMID:26958987

Comparative analyses on expression of galectins1-4, 7-10 and 12 in first trimester placenta, decidua and isolated trophoblast cells in vitro., PMID:26901464

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Human Gal-1/LGALS1 Antibody (8A12) [RHC40101]
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