Association of neurobiological and immune serum biomarkers with Toxoplasma gondii infection in patients with schizophrenia., PMID:40397143
Engineered extracellular vesicles with surface FGF21 and enclosed miR-223 for treating metabolic dysfunction-associated steatohepatitis., PMID:40209593
First-in-Human Study on Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Escalating Doses of HEC88473, a Novel Dual GLP-1 and FGF21 Receptor Agonist in Healthy and Obese Chinese Subjects., PMID:40175670
Advances in Oral Biomacromolecule Therapies for Metabolic Diseases., PMID:40006605
Establishment of a Direct Competitive ELISA for Camel FGF21 Detection., PMID:40005931
Clinical Trial: A Phase 2b Study to Evaluate the Efficacy and Safety of MK-3655 in Individuals With Pre-Cirrhotic MASH., PMID:39984821
Fibroblast growth factor 21 alleviated atopic march by inhibiting the differentiation of type 2 helper T cells., PMID:39798471
Novel FGF21 analogues through structure-based optimization for therapeutic development., PMID:39719877
Reduction of Hepatic Fat Content by Dulaglutide for the Treatment of Diabetes Mellitus: A Two-Centre Open, Single-Arm Trial., PMID:39718468
Construction and Expression of Fc-FGF21 by Different Expression Systems and Comparison of Their Similarity and Difference with Efruxifermin by In Vitro and In Vivo Studies., PMID:39699797
Chemogenetic activation of hepatic G12 signaling ameliorates hepatic steatosis and obesity., PMID:39542224
Therapeutic effects of FGF21 mimetic bFKB1 on MASH and atherosclerosis in Ldlr-/-.Leiden mice., PMID:39463193
Effects of Vitamin D-3 Supplementation During Pregnancy and Lactation on Maternal and Infant Biomarkers of Environmental Enteric Dysfunction, Systemic Inflammation, and Growth: A Secondary Analysis of a Randomized Controlled Trial., PMID:39278411
Liver-secreted FGF21 induces sarcopenia by inhibiting satellite cell myogenesis via klotho beta in decompensated cirrhosis., PMID:39226764
Polyneuropathy in systemic sclerosis: exploring the causes and biomarkers., PMID:39156689
Brown adipose tissue-derived FGF21 mediates the cardioprotection of dexmedetomidine in myocardial ischemia/reperfusion injury., PMID:39112671
Potent synergistic effects of dulaglutide and food restriction in prevention of olanzapine-induced metabolic adverse effects in a rodent model., PMID:38805968
BV2 Membrane-Coated PEGylated-Liposomes Delivered hFGF21 to Cortical and Hippocampal Microglia for Alzheimer's Disease Therapy., PMID:38513154
Safety and Efficacy of Efruxifermin in Combination With a GLP-1 Receptor Agonist in Patients With NASH/MASH and Type 2 Diabetes in a Randomized Phase 2 Study., PMID:38447814
Current status and future perspectives of FGF21 analogues in clinical trials., PMID:38423900
Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells., PMID:38309268
Lipodystrophy in methylmalonic acidemia associated with elevated FGF21 and abnormal methylmalonylation., PMID:38271099
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study., PMID:38172101
A specific nanobody-based affinity chromatography resin as a platform for small ubiquitin-related modifier fusion protein purification., PMID:38006661
Inflammatory related plasma proteins involved in acute preschool wheeze., PMID:38006384
Leptin Reduction as a Required Component for Weight Loss., PMID:37935033
Role of serum cytokines in the prediction of heart failure in patients with coronary artery disease., PMID:37608687
Investigation of CD56, ADAM17 and FGF21 Expressions in the Placentas of Preeclampsia Cases., PMID:37374349
Loss of epidermal glucocorticoid receptor protects against whole body metabolic dysfunction upon chronic corticosterone treatment., PMID:37364709
Noncompetitive immunoassay optimized for pharmacokinetic assessments of biologically active efruxifermin., PMID:37141854
Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia., PMID:37127348
The effect of fibroblast growth factor 21 on a mouse model of bovine viral diarrhea., PMID:36968461
A randomized, double-blind, placebo-controlled phase IIa trial of efruxifermin for patients with compensated NASH cirrhosis., PMID:36644237
Pemafibrate prevents choroidal neovascularization in a mouse model of neovascular age-related macular degeneration., PMID:36643635
The effects of a 20-week exercise program on blood-circulating biomarkers related to brain health in overweight or obese children: The ActiveBrains project., PMID:36529369
Safety, pharmacokinetics, and pharmacodynamics of pegozafermin in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 1b/2a multiple-ascending-dose study., PMID:36521501
Pancreatic alpha cell glucagon-liver FGF21 axis regulates beta cell regeneration in a mouse model of type 2 diabetes., PMID:36331598
Biomarkers of environmental enteric dysfunction and adverse birth outcomes: An observational study among pregnant women living with HIV in Tanzania., PMID:36130475
Fibroblast Growth Factor-Based Pharmacotherapies for the Treatment of Obesity-Related Metabolic Complications., PMID:36100222
Capillary Electrophoresis-Mass Spectrometry (CE-MS) by Sheath-Flow Nanospray Interface and Its Use in Biopharmaceutical Applications., PMID:35941476
Hepatocyte-Secreted Autotaxin Exacerbates Nonalcoholic Fatty Liver Disease Through Autocrine Inhibition of the PPARα/FGF21 Axis., PMID:35931383
X-linked hypophosphatemia, obesity and arterial hypertension: data from the XLH21 study., PMID:35758999
Asymptomatic SARS-CoV-2 Infection Is Associated With Higher Levels of Serum IL-17C, Matrix Metalloproteinase 10 and Fibroblast Growth Factors Than Mild Symptomatic COVID-19., PMID:35479098
Hepatic CPT1A Facilitates Liver-Adipose Cross-Talk via Induction of FGF21 in Mice., PMID:34957498
Hepatic CPT1A Facilitates Liver-Adipose Cross-Talk via Induction of FGF21 in Mice., PMID:34675003
Lower melanoma pulmonary metastatic burden in obese mice: role of FGF-21., PMID:34524221
Risk-Predictive and Diagnostic Biomarkers for Colorectal Cancer; a Systematic Review of Studies Using Pre-Diagnostic Blood Samples Collected in Prospective Cohorts and Screening Settings., PMID:34503217
ImmTOR nanoparticles enhance AAV transgene expression after initial and repeat dosing in a mouse model of methylmalonic acidemia., PMID:34485611
Efruxifermin in non-alcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a trial., PMID:34239138
Rat Milk and Plasma Immunological Profile throughout Lactation., PMID:33920419