Catalog No.
DHF06501
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Target
Epithelial membrane protein 2, EMP2, Protein XMP, XMP, EMP-2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P54851
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
PG-101, PG 101, PG101
Clone ID
PG-101
GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth., PMID:39794935
Epithelial Membrane Protein 2 (EMP2) Blockade Attenuates Pathological Neovascularization in Murine Oxygen-Induced Retinopathy., PMID:38958972
EMP2 Serves as a Functional Biomarker for Chemotherapy-Resistant Triple-Negative Breast Cancer., PMID:38672563
89Zr-ImmunoPET for the Specific Detection of EMP2-Positive Tumors., PMID:38417138
Exploring the Past, Present, and Future of Anti-Angiogenic Therapy in Glioblastoma., PMID:36765787
Epithelial membrane protein 2 (EMP2): A systematic review of its implications in pathogenesis., PMID:36455339
Epithelial membrane protein 2 (Emp2) modulates innate immune cell population recruitment at the maternal-fetal interface., PMID:33774530
EMP2 Is a Novel Regulator of Stemness in Breast Cancer Cells., PMID:32451329
Identification of epithelial membrane protein 2 (EMP2) as a molecular marker and correlate for angiogenesis in meningioma., PMID:31981014
Epithelial Membrane Protein-2 (EMP2) Antibody Blockade Reduces Corneal Neovascularization in an In Vivo Model., PMID:30646013
Epithelial membrane protein 2: a novel biomarker for circulating tumor cell recovery in breast cancer., PMID:30218306
Tissue microarray analysis for epithelial membrane protein-2 as a novel biomarker for gliomas., PMID:28887715
Epithelial membrane protein 2: Molecular interactions and clinical implications., PMID:28720310
EMP2 is a novel therapeutic target for endometrial cancer stem cells., PMID:28604744
Epithelial membrane protein-2 (EMP2) promotes angiogenesis in glioblastoma multiforme., PMID:28597184
Immunohistochemical expression of cytokeratins and epithelial membrane protein 2 in nasopharyngeal carcinoma and its potential implications., PMID:25684502
The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling., PMID:25169055
Epithelial membrane protein-2 (EMP2) activates Src protein and is a novel therapeutic target for glioblastoma., PMID:24644285
Rationale and preclinical efficacy of a novel anti-EMP2 antibody for the treatment of invasive breast cancer., PMID:24448822
Epithelial membrane protein 2 controls VEGF expression in ARPE-19 cells., PMID:23439602
EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF., PMID:23334331
Anti-EMP2 diabody blocks epithelial membrane protein 2 (EMP2) and FAK mediated collagen gel contraction in ARPE-19 cells., PMID:22728127
Positron emission tomography imaging of endometrial cancer using engineered anti-EMP2 antibody fragments., PMID:22585360
Epithelial membrane protein-2 (EMP2) and experimental proliferative vitreoretinopathy (PVR)., PMID:21591864
Rewiring integrin-mediated signaling and cellular response with the peripheral myelin protein 22 and epithelial membrane protein 2 components of the tetraspan web., PMID:21421883
Epithelial membrane protein-2 is a novel therapeutic target in ovarian cancer., PMID:20670949
Functional consequences of interactions between FAK and epithelial membrane protein 2 (EMP2)., PMID:19494199
Blockade of epithelial membrane protein 2 (EMP2) abrogates infection of Chlamydia muridarum murine genital infection model., PMID:19159428
Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines., PMID:19010852
FAK activation and the role of epithelial membrane protein 2 (EMP2) in collagen gel contraction., PMID:18469192
Steroid hormone regulation of EMP2 expression and localization in the endometrium., PMID:18400107
Epithelial membrane protein 2 modulates infectivity of Chlamydia muridarum (MoPn)., PMID:17544801
Design, synthesis, and evaluation of peptides with estrogen-like activity., PMID:15468062
The tetraspan protein EMP2 increases surface expression of class I major histocompatibility complex proteins and susceptibility to CTL-mediated cell death., PMID:12763482
Epithelial membrane protein-2 is expressed in discrete anatomical regions of the eye., PMID:12710941
The human malaria parasite Plasmodium falciparum exports the ATP-binding cassette protein PFGCN20 to membrane structures in the host red blood cell., PMID:9879889
Identification of a laminated layer-associated protein in Echinococcus multilocularis metacestodes., PMID:9585938