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Research Grade Anti-Human CX43/GJA1 (ALMB-0168)

Catalog #:   DHD23501 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHD23501

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

GJAL, Connexin-43, GJA1, Cx43, Gap junction 43 kDa heart protein, Gap junction alpha-1 protein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P17302

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

ALMB-0168, ALMB 0168, ALMB0168

Clone ID

ALMB-0168

Data Image
References

Glyoxal is a superior fixative to formaldehyde in promoting antigenicity and structural integrity in murine cardiac tissues., PMID:40485774

The Role of Fibroblast Growth Factor Receptor 2 as A Prognostic Biomarker in Colorectal Adenocarcinoma., PMID:40302086

Cx45 regulation by kinases and impact of expression in heart failure., PMID:40280467

Translationally controlled tumor protein interacts with connexin 43 and facilitates intercellular coupling between cardiomyocytes., PMID:40181823

IL-33 facilitates endoplasmic reticulum stress and pyroptosis in LPS-stimulated ARDS model in vitro., PMID:40118005

Osteocyte connexin hemichannels and prostaglandin E2 release dictate bone marrow mesenchymal stromal cell commitment., PMID:39937859

Unveiling the native architecture of adult cardiac tissue using the 3D-NaissI method., PMID:39907789

Extracellular Vesicles Released by Glioblastoma Cancer Cells Drive Tumor Invasiveness via Connexin-43 Gap Junctions., PMID:39883079

Differential substrate specificity of ERK, JNK, and p38 MAP kinases toward connexin 43., PMID:39798878

O-GlcNAcylation promotes astroglial-mesenchymal transition via the connexin43 pathway under high-glucose conditions., PMID:39672530

Activation of connexin hemichannels enhances mechanosensitivity and anabolism in disused and aged bone., PMID:39641271

Snail Expression as a Prognostic Factor in Colorectal Adenocarcinoma., PMID:39342593

Multiple approaches for the evaluation of connexin-43 expression and function in macrophages., PMID:39111361

Connexin hemichannels drive lactation-induced osteocyte acidification and perilacunar-canalicular remodeling., PMID:38935505

Antibody-activation of connexin hemichannels in bone osteocytes with ATP release suppresses breast cancer and osteosarcoma malignancy., PMID:38889005

Ovarian PERK/NRF2/CX43/StAR/progesterone pathway activation mediates female reproductive dysfunction induced by cold exposure., PMID:38702372

Granulysin-mediated reduction of PDZRN3 induces Cx43 gap junctions activity exacerbating skin damage in trichloroethylene hypersensitivity syndrome., PMID:38471344

Astroglial Cells: Emerging Therapeutic Targets in the Management of Traumatic Brain Injury., PMID:38247839

Differential substrate specificity of ERK, JNK, and p38 MAP kinases toward Connexin 43., PMID:38234737

Microdissection and Immunofluorescence Staining of Myocardial Sleeves in Murine Pulmonary Veins., PMID:38078615

Morphological and histological investigation of the conduction system in the equine atrial muscle sleeve of pulmonary veins., PMID:37658818

On-Slide Lambda Protein Phosphatase-Mediated Dephosphorylation of Fixed Samples., PMID:37367999

Regulation of Cx43 Gap Junction Intercellular Communication by Bruton's Tyrosine Kinase and Interleukin-2-Inducible T-Cell Kinase., PMID:37189407

The Relationship Between Expression of EpCAM Cancer Stem Cell Marker with Histopathological Grading, Lymphovascular Invasion, and Metastases in Colorectal Adenocarcinoma., PMID:36974547

Chondroitin Sulphate/Dermatan Sulphate Proteoglycans: Potential Regulators of Corneal Stem/Progenitor Cell Phenotype In Vitro., PMID:36768414

Ependyma: a new target for autoantibodies in neuromyelitis optica?, PMID:36751497

The protective effect of total glucosides of white paeony capsules on experimental autoimmune encephalomyelitis., PMID:36586141

Confocal Laser and Electron Microscopic Investigation of Gap Junctions in Anaplastic Astrocytomas., PMID:36527654

Evaluation of a connexin-based peptide for the treatment of age-related macular degeneration., PMID:36387470

Connexin 43 hemichannels regulate mitochondrial ATP generation, mobilization, and mitochondrial homeostasis against oxidative stress., PMID:36346745

The Heart's Pacemaker Mimics Brain Cytoarchitecture and Function: Novel Interstitial Cells Expose Complexity of the SAN., PMID:36182566

Trastuzumab and Doxorubicin Sequential Administration Increases Oxidative Stress and Phosphorylation of Connexin 43 on Ser368., PMID:35742818

Connexin 43 Hemichannels Regulate Osteoblast to Osteocyte Differentiation., PMID:35693933

"Orphan" Connexin43 in Plakophilin-2 Deficient Hearts Revealed by Volume Electron Microscopy., PMID:35663385

Protein and mRNA Quantification in Small Samples of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in 96-Well Microplates., PMID:35618896

Embedding a membrane protein into an enveloped artificial viral replica., PMID:35360888

Cx43 upregulation in HUVECs under stretch via TGF-β1 and cytoskeletal network., PMID:35350835

IL-17 upregulates MCP-1 expression via Act1 / TRAF6 / TAK1 in experimental autoimmune myocarditis., PMID:35183823

Connexin hemichannels with prostaglandin release in anabolic function of bone to mechanical loading., PMID:35132953

Heart Repair Induced by Cardiac Progenitor Cell Delivery within Polypyrrole-Loaded Cardiogel Post-ischemia., PMID:35007034

Platelet-rich plasma affects gap junctional features in myofibroblasts in vitro via vascular endothelial growth factor (VEGF)-A/VEGF receptor., PMID:34935228

Data on Connexin 43 hemichannels regulation of cellular redox in lens., PMID:34825036

Connexin Expression Is Altered in Liver Development of Yotari (dab1 -/-) Mice., PMID:34639052

Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer., PMID:34546978

SARS-CoV-2 Structural Proteins Exposure Alter Thrombotic and Inflammatory Responses in Human Endothelial Cells., PMID:34484458

Connexin mRNA distribution in adult mouse kidneys., PMID:34365513

Structural and functional relations between the connective tissue and epithelium of enamel organ and their role during enamel maturation., PMID:34100179

Investigating oligodendrocyte connexins: Heteromeric interactions between Cx32 and mutant or wild-type forms of Cx47 do not contribute to or modulate gap junction function., PMID:33835612

Collagen I Modifies Connexin-43 Hemichannel Activity via Integrin α2β1 Binding in TGFβ1-Evoked Renal Tubular Epithelial Cells., PMID:33807408

Danegaptide Prevents TGFβ1-Induced Damage in Human Proximal Tubule Epithelial Cells of the Kidney., PMID:33802083

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Anti-Human CX43/GJA1 (ALMB-0168) [DHD23501]
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