Catalog No.
DHE28302
Expression system
Mammalian Cells
Species reactivity
Human
Isotype
Fusion - [IL15RA (interleukin 15 receptor subunit alpha, CD215, IL-15RA)]2 - IGHG1 Fc (Fragment constant)
Target
IL15, IL-15, Interleukin-15
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P40933
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
ALT-803 (= inbakicept INN 11029 ([IL15RA]2-Fc) in complex 1:2 with nogapendekin alfa INN 11157 (IL15 D72)),[IL15RA]2-Fc, CAS: 2135939-52-3
Clone ID
Inbakicept
Current State of Bladder Preservation in High Grade Non-Muscle Invasive Bladder Cancer and Localized Muscle Invasive Bladder Cancer., PMID:40304944
Unmet Need in Non-muscle-invasive Bladder Cancer Failing Bacillus Calmette-Guérin Therapy: A Systematic Review and Cost-effectiveness Analyses from the International Bladder Cancer Group., PMID:39550339
Nogapendekin alfa inbakicept-PMLN: first approval milestone for BCG-unresponsive noninvasive bladder cancer: editorial., PMID:39525706
Novel intravesical therapies and delivery systems for the management of bladder cancer., PMID:39376040
Bladder-sparing Therapy for Bacillus Calmette-Guérin-unresponsive Non-muscle-invasive Bladder Cancer: International Bladder Cancer Group Recommendations for Optimal Sequencing and Patient Selection., PMID:39183090
Nogapendekin alfa Inbakicept: First Approval., PMID:38967714
In brief: Anktiva for bladder cancer., PMID:38905527
Quality of Life in the Phase 2/3 Trial of N-803 Plus Bacillus Calmette-Guérin in Bacillus Calmette-Guérin‒Unresponsive Nonmuscle-Invasive Bladder Cancer., PMID:38226931
IL-15 Superagonist NAI in BCG-Unresponsive Non-Muscle-Invasive Bladder Cancer., PMID:38320011
For research use only. Not for human or drug use.
