Research Grade Anti-Human MET/c-Met/HGFR (SAIT301)

Catalog No.

DHC34212

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

Tyrosine-protein kinase Met, Hepatocyte growth factor receptor, Proto-oncogene c-Met, Scatter factor receptor, HGF receptor, SF receptor, HGF/SF receptor, MET

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P08581

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

SAIT301

Clone ID

SAIT301

Phase I Trial of Anti-MET Monoclonal Antibody in MET-Overexpressed Refractory Cancer., PMID:29551559

Gastrointestinal malignancies harbor actionable MET exon 14 deletions., PMID:26375439

USP8 modulates ubiquitination of LRIG1 for Met degradation., PMID:24828152

Met degradation by SAIT301, a Met monoclonal antibody, reduces the invasion and migration of nasopharyngeal cancer cells via inhibition of EGR-1 expression., PMID:24722284

Synthetic lethal screening reveals FGFR as one of the combinatorial targets to overcome resistance to Met-targeted therapy., PMID:24662823

Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met-targeting antibody., PMID:23208509

Document Download

Research Grade Anti-Human MET/c-Met/HGFR (SAIT301).pdf