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Research Grade Anti-Human MET/c-Met/HGFR (REGN5093)

Catalog #:   DHC34210 Specific References (4) DATASHEET
Host species: Human
Isotype: IgG
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHC34210

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

Tyrosine-protein kinase Met, Hepatocyte growth factor receptor, Proto-oncogene c-Met, Scatter factor receptor, HGF receptor, SF receptor, HGF/SF receptor, MET

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P08581

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

REGN5093

Clone ID

REGN5093

Data Image
References

Anti-MET Antibody Therapies in Non-Small-Cell Lung Cancer: Current Progress and Future Directions., PMID:39449330

REGN5093-M114: can an antibody-drug conjugate overcome the challenge of resistance to epidermal growth factor receptor and mesenchymal epithelial transition tyrosine kinase inhibitors in non-small cell lung cancer?, PMID:39263036

Engineering hydrophobicity and manufacturability for optimized biparatopic antibody-drug conjugates targeting c-MET., PMID:38214660

Preclinical Study of a Biparatopic METxMET Antibody-Drug Conjugate, REGN5093-M114, Overcomes MET-driven Acquired Resistance to EGFR TKIs in EGFR-mutant NSCLC., PMID:36269795

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Anti-Human MET/c-Met/HGFR (REGN5093) [DHC34210]
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