Catalog No.
PHA85201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human KLK8 (Gln29-Gly260).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Serine protease 19,TADG14,Tumor-associated differentially expressed gene 14 protein,Serine protease TADG-14,NP,NRPN,KLK8,Neuropsin,Kallikrein-8,hK8,PRSS19,Ovasin
Purification
Purified by antigen affinity column.
Accession
O60259
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A novel role of kallikrein-related peptidase 8 in the pathogenesis of diabetic cardiac fibrosis., PMID:33754057
Genetic knockdown of Klk8 has sex-specific multi-targeted therapeutic effects on Alzheimer's pathology in mice., PMID:33341972
Inhibition of excessive kallikrein-8 improves neuroplasticity in Alzheimer's disease mouse model., PMID:31734318
A cardinal sin when researching neuropsin/KLK8: Thou shalt validate antibodies., PMID:28732191
Acute systemic rapamycin induces neurobehavioral alterations in rats., PMID:25043732
Expression of kallikrein-related peptidases (KRP/hK5, 7, 6, 8) in subtypes of human lung carcinoma., PMID:18182244
Activation of proteinase-activated receptor-2 by human kallikrein-related peptidases., PMID:17625593
Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients., PMID:17518992
Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases., PMID:16086736
[Kallikrein-family serine protease in the central nervous system]., PMID:14531278
Human kallikrein 8: immunoassay development and identification in tissue extracts and biological fluids., PMID:12507964
Neuropsin regulates an early phase of schaffer-collateral long-term potentiation in the murine hippocampus., PMID:10762375
Plasticity-related serine proteases in the brain (review)., PMID:10085414
Blockade of neuropsin, a serine protease, ameliorates kindling epilepsy., PMID:9749739
Expression of neuropsin in the keratinizing epithelial tissue-immunohistochemical analysis of wild-type and nude mice., PMID:9620300