Modified Citrus Pectin Alleviates Diabetic Kidney Disease by Suppressing Pyroptosis in Renal Tubular Epithelial Cells via the Cx43-ERK1/2 Signaling Pathway., PMID:40460282
Overexpression of thioredoxin 1 contributes to neuroprotection through ATM activation and pentose phosphate pathway modulation after traumatic brain injury., PMID:40449785
IL-6-induced long noncoding RNA MIR3142HG promotes tumorigenesis by interacting with thioredoxin-1 and STAT3 in human colorectal cancer., PMID:40405062
Characterization of molecular features, antioxidant capacity, and immunological function of thioredoxin 1 (Trx1) in chub mackerel (Scomber japonicus)., PMID:40404032
Thioredoxin-1 inhibits NLRP3-mediated pyroptosis by regulating TXNIP in models of Alzheimer's disease., PMID:40360637
High Hcy regulates fluid shear stress pathway activity through histone H3K79 homocysteinylation in hyperhomocysteinemia-related child hypertension., PMID:40346632
Redox homeostasis and inflammation in fibroblasts of patients with Friedreich Ataxia: a possible cross talk., PMID:40308559
Trp31 Residue of Trx-1 Is Essential for Maintaining Antioxidant Activity and Cellular Redox Defense Against Oxidative Stress., PMID:40227210
Disrupting reconsolidation by systemic inhibition of Thioredoxin-1 attenuates cocaine and morphine relapse., PMID:40199134
Thioredoxin-1 Downregulation in the SNpc Exacerbates the Cognitive Impairment Induced by MPTP., PMID:40135707
Oxidative stress markers 8-OHdG, Trx-1, and Prx6 are expressed in seminoma and are connected to TXNDC2, 3, and 6 expression levels., PMID:40091773
Unraveling the multifaceted roles of peroxiredoxins in sickle cell anemia: implications in redox and inflammation adaptations., PMID:40085210
Novel Systematic Design of Asymmetric Flexible Transceiver Coils with Optimal Wireless Power Transfer for Biomedical Implants., PMID:40039085
A randomized controlled trial of conventional GVHD prophylaxis with or without teprenone for the prevention of severe acute GVHD., PMID:39994018
Polysulfides promote protein disulfide bond formation in microorganisms growing under anaerobic conditions., PMID:39918318
Conformational activation and disulfide exchange in HIV-1 Env induce cell-free lytic/fusogenic transformation and enhance infection., PMID:39912667
Cotargeting of thioredoxin 1 and glutamate-cysteine ligase in both imatinib-sensitive and imatinib-resistant CML cells., PMID:39832669
Bi-targeting of thioredoxin 1 and telomerase by thiotert promotes cell death of myelodysplastic syndromes and lymphoma., PMID:39815362
High mRNA Expression of 24 Dehydrocholesterol Reductase (DHCR24) in the Treatment of Doxorubicin-Induced Heart Failure in Rats., PMID:39796168
Serum T2-High Inflammation Mediators in Eosinophilic COPD., PMID:39766355
Nano Acacetin Mitigates Intestinal Mucosal Injury in Sepsis Rats by Protecting Mitochondrial Function and Regulating TRX1 to Inhibit the NLRP3 Pyroptosis Pathway., PMID:39759963
PX-12 modulates vorinostat-induced acetylation and methylation marks in CAL 27 cells., PMID:39716806
Hyperoside alleviates depressive-like behavior in social defeat mice by mediating microglial polarization and neuroinflammation via TRX1/NLRP1/Caspase-1 signal pathway., PMID:39647288
Soluble guanylyl cyclase, the NO-receptor, regulates endothelium-dependent vascular relaxation via its transnitrosation activity., PMID:39554196
Tsa1 is the dominant peroxide scavenger and a source of H2O2-dependent GSSG production in yeast., PMID:39515595
Oxidative and endoplasmic reticulum stress in diabetes-related hearing loss: Protective effects of thioredoxin., PMID:39515416
[Curcumin alleviates septic lung injury in mice by inhibiting TXNIP/TRX-1/GPX4-mediated ferroptosis]., PMID:39505349
Thioredoxin-1 protein interactions in neuronal survival and neurodegeneration., PMID:39454970
The Role of Thioredoxin System in Shank3 Mouse Model of Autism., PMID:39347996
Diallyl trisulfide alleviates dextran sulphate sodium-induced colitis in mice by inhibiting NLRP3 inflammasome activation via ROS/Trx-1 pathway., PMID:39324280
Chrysophanol-mediated trx-1 activation attenuates renal fibrosis through inhibition of the JNK/Cx43 signaling pathway., PMID:39238246
Molecular Hydrogen and Extracorporeal Gas Exchange: A Match Made in Heaven? An In Vitro Pilot Study., PMID:39200347
Unveiling the anticancer potential of Pestalotioprolide E, an unexplored macrolide: Targeting TRXR1-TRX1-ASK1-P38 signaling cascade in triple-negative breast cancer., PMID:39173682
Calycosin activates Nrf2/Keap1 signaling to ameliorate hydrogen peroxide-induced spinal cord neuron death and mitochondrial dysfunction., PMID:39132830
TrxR1 is involved in the activation of Caspase-11 by regulating the oxidative-reductive status of Trx-1., PMID:39059206
Enzymatic characterization of five thioredoxins and a thioredoxin reductase from Myxococcus xanthus., PMID:39038987
Thioredoxin-1 Protects Neurons Through Inhibiting NLRP1-Mediated Neuronal Pyroptosis in Models of Alzheimer's Disease., PMID:38976128
Sinensetin, a polymethoxyflavone from citrus fruits, ameliorates LPS-induced acute lung injury by suppressing Txnip/NLRP3/Caspase-1/GSDMD signaling-mediated inflammatory responses and pyroptosis., PMID:38938065
Subcellular Localization of Thioredoxin/Thioredoxin Reductase System-A Missing Link in Endoplasmic Reticulum Redox Balance., PMID:38928353
Characterize direct protein interactions with enrichable, cleavable and latent bioreactive unnatural amino acids., PMID:38890329
Reactions of Cisplatin with Thioredoxin-1 Regulate Intracellular Redox Homeostasis., PMID:38850241
The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity., PMID:38821952
High‑oxygen-modified atmospheric packaging delays flavor and quality deterioration in fresh-cut broccoli., PMID:38703670
Helicobacter pylori with trx1 high expression promotes gastric diseases via upregulating the IL23A/NF-κB/IL8 pathway., PMID:38686467
Colorimetric and Electrochemical Dual-Mode Detection of Thioredoxin 1 Based on the Efficient Peroxidase-Mimicking and Electrocatalytic Property of Prussian Blue Nanoparticles., PMID:38667178
Glutamate rescues heat stress-induced apoptosis of Sertoli cells by enhancing the activity of antioxidant enzymes and activating the Trx1-Akt pathway in vitro., PMID:38642435
Exocarpium Citri Grandis ameliorates LPS-induced acute lung injury by suppressing inflammation, NLRP3 inflammasome, and ferroptosis., PMID:38588989
Hydrogen alleviates impaired lung epithelial barrier in acute respiratory distress syndrome via inhibiting Drp1-mediated mitochondrial fission through the Trx1 pathway., PMID:38554812
The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1., PMID:38536085
Thioredoxins o1 and h2 jointly adjust mitochondrial dihydrolipoamide dehydrogenase-dependent pathways towards changing environments., PMID:38518065
For research use only. Not for human or drug use.
