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Research Grade Anti-Human CD26/DPP4 (YS110)

Catalog #:   DHD74102 Specific References (14) DATASHEET
Host species: Human
Isotype: IgG
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHD74102

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

TP103, Dipeptidyl peptidase IV, ADABP, Dipeptidyl peptidase 4, CD26, DPP4, Dipeptidyl peptidase IV soluble form, Dipeptidyl peptidase IV membrane form, DPP IV, ADCP2, Adenosine deaminase complexing protein 2, ADCP-2, T-cell activation antigen CD26

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P27487

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

YS110

Clone ID

YS110

Data Image
References

Development of a Novel CD26-Targeted Chimeric Antigen Receptor T-Cell Therapy for CD26-Expressing T-Cell Malignancies., PMID:37626869

Phase 2 Study of YS110, a Recombinant Humanized Anti-CD26 Monoclonal Antibody, in Japanese Patients With Advanced Malignant Pleural Mesothelioma., PMID:34590026

Serum soluble CD26/DPP4 titer variation is a potential prognostic biomarker in cancer therapy with a humanized anti-CD26 antibody., PMID:33757558

Phase I study of YS110, a recombinant humanized monoclonal antibody to CD26, in Japanese patients with advanced malignant pleural mesothelioma., PMID:31557561

Novel Antibody-Drug Conjugate with Anti-CD26 Humanized Monoclonal Antibody and Transcription Factor IIH (TFIIH) Inhibitor, Triptolide, Inhibits Tumor Growth via Impairing mRNA Synthesis., PMID:31398954

Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens., PMID:31194830

Monoclonal antibody YS110 for refractory solid tumours., PMID:28343974

First-in-human phase 1 of YS110, a monoclonal antibody directed against CD26 in advanced CD26-expressing cancers., PMID:28291776

[Development of New Therapy for Malignant Mesothelioma Based on CD26 Molecule]., PMID:27431629

A humanized anti-CD26 monoclonal antibody inhibits cell growth of malignant mesothelioma via retarded G2/M cell cycle transition., PMID:27134571

Establishment of monoclonal anti-human CD26 antibodies suitable for immunostaining of formalin-fixed tissue., PMID:24502396

Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody., PMID:24067970

Nuclear localization of CD26 induced by a humanized monoclonal antibody inhibits tumor cell growth by modulating of POLR2A transcription., PMID:23638030

Pichia garciniae sp. nov., isolated from a rotten mangosteen fruit (Garcinia mangostana L., Clusiaceae)., PMID:18984711

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Anti-Human CD26/DPP4 (YS110) [DHD74102]
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