Research Grade Anti-Human CD24 (ATG 031)

Catalog No.

DHD65201

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

Signal transducer CD24, CD24, CD24A, Small cell lung carcinoma cluster 4 antigen

Concentration

1.85mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P25063

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

ATG-031, ATG 031, ATG031

Clone ID

ATG 031

Peripheral memory B cell population maintenance and long-term survival after perioperative chemoimmunotherapy in NSCLC (NADIM trial)., PMID:40468805

Defective neutrophil clearance in JAK2V617F myeloproliferative neoplasms drives myelofibrosis via immune checkpoint CD24., PMID:40373279

N-deglycosylation targeting chimera (DGlyTAC): a strategy for immune checkpoint proteins inactivation by specifically removing N-glycan., PMID:40289109

CD24-targeted CAR-T cells mediated long-term anti-tumor efficacy through activation of endogenous tumor immune responses., PMID:40105191

Neutrophil extracellular traps impede cancer metastatic seeding via protease-activated receptor 2-mediated downregulation of phagocytic checkpoint CD24., PMID:40010762

Deep profiling of B cells responding to various pathogens uncovers compartments in IgG memory B cell and antibody-secreting lineages., PMID:39970201

ADARp110 promotes hepatocellular carcinoma progression via stabilization of CD24 mRNA., PMID:39808660

Dual-target magneto-immunoassay with bifunctional nanohybrids for breast cancer exosome detection., PMID:39788070

CD47 predominates over CD24 as a macrophage immune checkpoint in cancer., PMID:39651307

PPAB001, a novel bispecific antibody against CD47 and CD24, enhances anti-PD-L1 efficacy in triple-negative breast cancer via reprogramming tumor-associated macrophages towards M1 phenotype., PMID:39622130

Identification of the central tolerance checkpoint for autoreactive proteinase 3+ B cells in human bone marrow., PMID:39549483

Is modulation of immune checkpoints on glioblastoma-infiltrating myeloid cells a viable therapeutic strategy?, PMID:39427326

Phenotypic Characterization of B-Lymphocyte Subpopulations in Human Peripheral Blood: A Cost-Effective Seven-Color One-Tube Protocol., PMID:39348052

Immune Cell Profiles of Patients with Sickle Cell Disease during Parvovirus B19-Induced Transient Red Cell Aplasia., PMID:39340016

The missing link between cancer stem cells and immunotherapy., PMID:39316769

Sensitive phenotyping of serum extracellular vesicles on a SERS-microfluidic platform for early-stage clinical diagnosis of ovarian carcinoma., PMID:39260102

Human circulating CD24hi marginal zone B cells produce IgM targeting atherogenic antigens and confer protection from vascular disease., PMID:39196097

Evolution of pathologic B-cell subsets and serum environment-specific sIgEs in patients with atopic dermatitis and controls, from infancy to adulthood., PMID:39003573

An in-situ peptide-antibody self-assembly to block CD47 and CD24 signaling enhances macrophage-mediated phagocytosis and anti-tumor immune responses., PMID:38971872

Exosomes multiplex profiling, a promising strategy for early diagnosis of laryngeal cancer., PMID:38902710

Sonocatalytic oncolysis microbiota curb intrinsic microbiota lactate metabolism and blockade CD24-Siglec10 immune escape to revitalize immunological surveillance., PMID:38878482

Increased IgD and CD27 Double Negative (DN) B cell population in pediatric onset autoimmune hepatitis., PMID:38770919

A multifunctional antibody fusion protein 57103 targeting CD24, IL-4R, and αvβ3 for treating cancer and regulating the tumor microenvironment., PMID:38761419

Apoptosis in Postmortal Tissues of Goat Spinal Cords and Survival of Resident Neural Progenitors., PMID:38731901

Site-specific Antibody-Nitric Oxide Conjugate HN02 Possesses Improved Antineoplastic and Safety Properties., PMID:38557756

Peg-IFNα combined with hepatitis B vaccination contributes to HBsAg seroconversion and improved immune function., PMID:38555445

Anti-IL-8 monoclonal antibodies inhibits the autophagic activity and cancer stem cells maintenance within breast cancer tumor microenvironment., PMID:38552109

Checkpoint CD24 function on tumor and immunotherapy., PMID:38487533

The response of CD27+CD38+ plasmablasts, CD24hiCD38hi transitional B cells, CXCR5-ICOS+PD-1+ Tph, Tph2 and Tfh2 subtypes to allergens in children with allergic asthma., PMID:38424520

A highly susceptible hACE2-transgenic mouse model for SARS-CoV-2 research., PMID:38389533

Targeting CD24/Siglec-10 signal pathway for cancer immunotherapy: recent advances and future directions., PMID:38279998

In vitro B cell experiments explore the role of CD24, CD38, and energy metabolism in ME/CFS., PMID:38259473

Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth., PMID:38242888

Targeting CD24 in Cancer Immunotherapy., PMID:38137380

FLAER as a standalone reagent for paroxysmal nocturnal hemoglobinuria: Do we need to reconsider the guidelines for testing?, PMID:38069562

Dual blockade of CD47 and CD24 signaling using a novel bispecific antibody fusion protein enhances macrophage immunotherapy., PMID:38046893

RARγ promotes the invasion and metastasis of thyroid carcinoma by activating the JAK1-STAT3-CD24/MMPs axis., PMID:37897947

Dual antibody-aided mesoporous nanoreactor for H2O2 self-supplying chemodynamic therapy and checkpoint blockade immunotherapy in triple-negative breast cancer., PMID:37875918

IMM47, a humanized monoclonal antibody that targets CD24, exhibits exceptional anti-tumor efficacy by blocking the CD24/Siglec-10 interaction and can be used as monotherapy or in combination with anti-PD1 antibodies for cancer immunotherapy., PMID:37846296

Immunological Responses of Arsenicum album 30CH to Combat COVID-19: Protocol for a Double-Blind, Randomized, Placebo-Controlled Clinical Trial in the Pathanamthitta District of Kerala., PMID:37843912

Cancer stem cells are prevalent in the basal-like 2 and mesenchymal triple-negative breast cancer subtypes in vitro., PMID:37771376

Autoreactive B cells in rheumatoid arthritis include mainly activated CXCR3+ memory B cells and plasmablasts., PMID:37725442

15-color highly sensitive flow cytometry assay for post anti-CD19 targeted therapy (anti-CD19-CAR-T and blinatumomab) measurable residual disease assessment in B-lymphoblastic leukemia/lymphoma: Real-world applicability and challenges., PMID:37706583

Effects of blocking CD24 and CD47 'don't eat me' signals in combination with rituximab in mantle-cell lymphoma and chronic lymphocytic leukaemia., PMID:37654003

Stem cell markers: A guide to neoadjuvant therapy in breast carcinomas., PMID:37530329

Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton., PMID:37524694

Renal Tubular CD24 Upregulation Aggravates Folic Acid Induced Acute Kidney Injury: A Possible Role for T Regulatory Cells Inhibition in Mice., PMID:37511747

New hope for tumor immunotherapy: the macrophage-related "do not eat me" signaling pathway., PMID:37484024

Five-year follow-up of a phase I trial of donor-derived modified immune cell infusion in kidney transplantation., PMID:37483623

CD24 is a novel target of chimeric antigen receptor T cells for the treatment of triple negative breast cancer., PMID:37418008

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