Catalog No.
DHD10812
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG
Clonality
Monoclonal
Target
CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P15391
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
AMG-562, AMG 562, AMG562, bispecific
Clone ID
AMG 562
Clinical, tumor and product features associated with outcomes after axicabtagene ciloleucel therapy in follicular lymphoma., PMID:40536814
Current state-of-the-art of immunotherapy in follicular lymphoma., PMID:40534532
Bioinformatics-based identification of key genes for Olaparib resistance in breast cancer: prognostic implications and therapeutic relevance., PMID:40531367
Effect of glycemic control on lymphocyte subsets in the dissemination of pulmonary tuberculosis: A retrospective analysis., PMID:40530083
Selinexor Reduces the Immunosuppression of Macrophages and Synergizes With CD19 CAR-T Cells Against B-Cell Lymphoma., PMID:40528279
Heavily Pretreated Refractory Diffuse Large B-Cell Lymphoma Successfully Treated with Epcoritamab: Case Report., PMID:40524964
Immune cell aberrations in Systemic Lupus Erythematosus: navigating the targeted therapies toward precision management., PMID:40524185
Correlation with CD79B expression and clinicopathological parameters including cell of origin, CD79A and CD19 expression, and CD79B mutation in diffuse large B-cell lymphoma., PMID:40523447
Unsupervised Machine Learning-Based Process Analytical Tools for Near Real-Time Cell Morphology Analysis During CAR-T Cell Manufacturing., PMID:40519185
Co-expression of IL-15 and CCL21 strengthens CAR-NK cells to eliminate tumors in concert with T cells and equips them with PI3K/AKT/mTOR signal signature., PMID:40518288
Beyond BCL2 (B cell lymphoma) and BTK (Bruton tyrosine kinase) inhibitors: novel agents and resistance mechanisms for chronic lymphocytic leukemia., PMID:40515863
Pharmacokinetic-pharmacodynamic modelling in a clinical pilot study of rituximab in multiple sclerosis: Towards personalized dosing interval., PMID:40515509
[Modern systemic treatment-bispecific antibodies and CAR-T cell therapy : Clinical management, mechanisms of action, outcomes]., PMID:40514410
CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma., PMID:40513575
Pharmacokinetics, Receptor Occupancy, and Pharmacodynamics of Obexelimab Following Intravenous Administration in Adult Healthy Volunteers and in Patients With Rheumatoid Arthritis., PMID:40512061
Perspectives on T-cell engaging therapies in relapsed/refractory indolent non-Hodgkin lymphoma., PMID:40511598
Case Report: Flow cytometric differential diagnosis of a peripheral T-cell lymphoma, NOS with complete loss of CD45 and dim expression of CD3., PMID:40510503
Influence of Ovophospholipids on Lymphocyte Subsets and Humoral Immune Response in Mice., PMID:40509141
Radiomic Features Prognosticate Treatment Response in CAR-T Cell Therapy., PMID:40507312
Sex-specific immune alterations in mice following long-term simulated microgravity and chronic irradiation., PMID:40506441
Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor That Unleashes PD-1 Checkpoint and CAR T-Cell Immunotherapies., PMID:40506249
Increased Effector Memory CD4+ T Cells Are Associated with Chronic Childhood Immune Thrombocytopenia., PMID:40505868
Comparison of the safety profiles of CD19-targeting CAR T-cell therapy in patients with SLE and B-cell lymphoma., PMID:40504989
Identification of CD19+B Cell as a Diagnostic Biomarker in Sepsis-Induced ARDS., PMID:40503488
QSP modeling of loncastuximab tesirine with T-cell-dependent bispecific antibodies guides dose-regimen strategy., PMID:40500294
BCMA-Targeted T-Cell Engager for Autoimmune Hemolytic Anemia after CD19 CAR T-Cell Therapy., PMID:40499177
Gut microbiota modulation through Akkermansia spp. supplementation increases CAR-T cell potency., PMID:40498998
Expression of the Transcription Factor FOXP3 in Human Peripheral Blood B-Cell Subtypes (CD19+CD39+ and CD19+CD39-) and Evaluation of Their Regulatory Function., PMID:40497715
A Rare Case of Follicular Lymphoma with both Malignant Pleural Effusion and Ascites., PMID:40497627
Effect of Cumulative Exposure to Ocrelizumab on Memory B-Cell Repopulation Dynamics in Multiple Sclerosis., PMID:40497506
Differential susceptibility and role for senescence in CART cells based on costimulatory domains., PMID:40495168
Treatment of Older Adults with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia., PMID:40494331
Development of an in situ CAR-T cell protocol through optical and PSMA-targeted PET imaging., PMID:40493195
CD28 signaling domain boosts persistence and in vivo anti-tumor activity of stem cell-derived CD19-CAR-NK cells., PMID:40491480
Blinatumomab Use in Pediatric B-ALL: Where are we now?, PMID:40489801
Monitoring anti-Rituximab antibodies in myasthenia gravis affects the time to event during Rituximab treatment., PMID:40488894
Impact of neurotoxicity and steroid therapy on cancer progression-free survival in lymphoma patients treated with anti-CD19 CAR T cells., PMID:40487586
Enhanced anti-tumor activity by zinc finger repressor-driven epigenetic silencing of immune checkpoints and TGFBR2 in CAR-T cells and TILs., PMID:40487483
Persistent B Cell Depletion After Rituximab for Autoimmune and Glomerular Diseases: A Case Series., PMID:40485690
Pharmacovigilance analysis of secondary primary malignancies and antibiotic interactions in CAR-T cell therapies., PMID:40485666
From myth to bedside: a scoping review of the applications of the chimeric antigen receptor in rheumatology., PMID:40481370
CAR-T cell therapy in older adults with relapsed/refractory LBCL: benefits and challenges., PMID:40480655
Higher frequencies of age-associated B-cells in early arthritis are linked to atherosclerosis and immune circuits-a potential role as a biomarker for risk stratification., PMID:40478777
Physiochemical and transcriptomics of exotic holstein friesian cattle in Pakistani subtropics., PMID:40478316
CBD promotes antitumor activity by modulating tumor immune microenvironment in HPV associated head and neck squamous cell carcinoma., PMID:40475776
Kinetics of CD19+ B-cell depletion post-rituximab in membranous nephropathy., PMID:40474985
An exploration of the initiation time and patient selection of PD-1 inhibitors/PD-1 inhibitors combined with chemotherapy as salvage therapy in R/R DLBCL patients after anti-CD19-CAR T-cell therapy., PMID:40474425
Case Report: Collision Tumor Involving Diffuse Large B-Cell Lymphoma (DLBCL) and Meningioma., PMID:40474366
Efficacy and safety of a novel CD19, CD22 dual-targeted fully human loop bi-CAR-T for the treatment of relapsed/refractory B cell non-Hodgkin lymphoma., PMID:40474279
Advances in the treatment of ANCA-associated vasculitis., PMID:40473820
For research use only. Not for human or drug use.
